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Webcast
Geron 2018 Annual Meeting of Stockholders
May 15, 2018 at 4:00 PM PDT
Webcast Presentation

Geron 2018 Annual Meeting of Stockholders
May 15, 2018 at 4:00 PM PDT

Corporate Profile

Geron is a clinical stage biopharmaceutical company developing a first-in-class telomerase inhibitor, imetelstat, in hematologic myeloid malignancies. Imetelstat is currently being tested in two clinical trials: IMbark™, a Phase 2 trial in myelofibrosis (MF) and IMerge™, a Phase 2/3 trial in myelodysplastic syndromes (MDS). These clinical trials are being conducted by Janssen Biotech, Inc., under a collaboration and license agreement, in which Janssen were granted the exclusive rights to develop and commercialize imetelstat worldwide for all indications in oncology, including hematologic myeloid malignancies, and all other human therapeutic uses.

Telomerase is an enzyme that enables cancer cells, including malignant progenitor cells, to maintain telomere length, which provides them with the capacity for limitless, uncontrolled proliferation. Using Geron’s proprietary nucleic acid chemistry, imetelstat was designed as an oligonucleotide that targets and binds with high affinity to the active site of telomerase, thereby directly inhibiting telomerase activity and impeding malignant cell proliferation. Early clinical data, including molecular responses in essential thrombocythemia (ET) and remissions, including reversal of bone marrow fibrosis in MF, suggest imetelstat may have disease-modifying activity by inhibiting the progenitor cells of the malignant clones for the underlying diseases.

Recent News

Date Title and Summary  
Toggle Summary Studies Show Geron´s Stem Cell Therapeutic for Spinal Cord Injury Produces Nerve Growth Factors
Findings Published in Stem Cells and Development Indicate GRNOPC1 Promotes Survival and Regeneration of Neurons Damaged During Spinal Cord Injury MENLO PARK, Calif., Jan. 17, 2007 – Geron Corporation (Nasdaq: GERN) today reported that studies show GRNOPC1, the company’s human embryonic stem cell
Toggle Summary Geron Corporation to Present at BIO CEO & Investor Conference
MENLO PARK, Calif., Feb. 9, 2007 – Geron Corporation (Nasdaq: GERN) will present an update of the company’s product development programs at 1:15 p.m. ET on Monday, Feb. 12, 2007, at the BIO CEO & Investor Conference in New York City. The update of Geron’s portfolio of telomerase–based anti–cancer
Toggle Summary Unique Structure of Geron´s Telomerase Inhibitor Drug Promotes Anti-Tumor, Anti-Metastatic Activity in Lung Cancer Cells
MENLO PARK, Calif., Feb. 15, 2007 – Geron Corporation (Nasdaq: GERN) today announced the publication of preclinical data that show specific structural elements of GRN163L contribute to its unique anti–tumor and anti–metastatic activity. Published in Cancer Research (2007; 67: 1121–29), the studies

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CG Capital
877-889-1972

investor@geron.com