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http://fasb.org/us-gaap/2025#SecuredOvernightFinancingRateSofrMember 0.3333 10-K true 2025-12-31 --12-31 false 000-20859 GERON CORP DE 75-2287752 919 East Hillsdale Blvd. Suite 250 Foster City CA 94404 650 473-7700 Common Stock, $0.001 par value GERN NASDAQ Yes No Yes Yes Large Accelerated Filer false false true false false 860500000 640544661 <span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:212.65pt;position:var(--position);text-decoration:none;white-space:pre">DOCUMENTS INCORPORATED BY REFERENCE:</span><div style="position:var(--position);top:128.8pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:426.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td></tr><tr style="height:20.25pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:426.75pt"><div><div style="line-height:7pt;position:var(--position);top:12.5pt;width:426.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:7pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Document</span></div></div></div></td><td style="border-bottom:0.5pt solid #ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:429.75pt;position:var(--position);width:65.25pt"><div><div style="line-height:7pt;position:var(--position);top:4.1pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:7pt;font-style:normal;font-weight:bold;left:15.98pt;position:var(--position);text-decoration:none;white-space:pre">Form 10‑K</span></div><div style="line-height:7pt;position:var(--position);top:12.5pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:7pt;font-style:normal;font-weight:bold;left:24.66pt;position:var(--position);text-decoration:none;white-space:pre">Parts</span></div></div></div></td></tr><tr style="height:23.25pt"><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:20.25pt;width:426.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.75pt;width:426.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Portions of the Registrant’s definitive proxy statement for the 2026 annual meeting of stockholders to be filed pursuant to </span></div><div style="line-height:8pt;position:var(--position);top:13.35pt;width:426.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Regulation 14A within 120 days of the Registrant’s fiscal year ended December 31, 2025.</span></div></div></div></td><td style="border-top:0.5pt solid #ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:429.75pt;position:var(--position);top:20.25pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:28.63pt;position:var(--position);text-decoration:none;white-space:pre">III</span></div></div></div></td></tr></tbody></table></div></div></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Risk management and strategy</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We operate in the biopharmaceutical sector, which is a highly regulated sector subject to various </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity risks that could adversely affect our business, financial condition, and results of operations, including </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">intellectual property theft; fraud; extortion; harm to employees or customers; disruption of our clinical trials, manufacturing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">or supply chain; violation of privacy laws and other litigation and legal risk; and reputational risk. We rely primarily on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">industry-leading third parties and a cloud-based infrastructure for our information technology systems, and accordingly are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">dependent on these third parties’ own cybersecurity risk management practices and strategy. We have implemented and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">maintain various information security processes designed to identify, assess and manage material risks from cybersecurity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">threats to our critical computer networks, third party hosted services, communications systems, hardware and software, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our critical data, including clinical trial data, intellectual property, confidential information that is proprietary, strategic, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">financial or competitive in nature, and personal data (“Information Systems and Data”).</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We take a risk-based approach to identify and assess the cybersecurity threats and risks that could affect our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">business and Information Systems and Data. Our Information Technology personnel help identify, assess and manage our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity threats and risks, and support our efforts to identify and assess risks from cybersecurity threats by monitoring </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and evaluating our threat environment. We use various methods and tools to identify, assess and manage cybersecurity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:517.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">threats and risks, including, for example, automated tools, a third-party managed detection and response firm to monitor </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:529.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">security alerts on a 24-hour basis, industry reports, engaging a virtual Chief Information Security Officer, third party threat </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:541.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">assessments and penetration testing. In addition, we encrypt data at rest and maintain network security controls, such as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">firewalls and virtual private networks. We also conduct computerized system monitoring and access control, including </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">asset management, tracking and disposal associated with onboarding and offboarding of personnel. We maintain </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity insurance.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Depending on the environment, we implement and maintain various technical, physical, and organizational </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">measures, processes, standards and policies designed to manage and mitigate material risks from cybersecurity threats to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our Information Systems and Data. For example, in 2025, we expanded our monitoring capabilities by engaging with a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">managed detection and response firm to monitor and respond to security alerts on a 24-hour, seven-day-a-week basis.  We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:649.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have implemented and maintain an incident response plan, and we utilize automated tools designed to maintain email </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:661.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">security. We have also implemented a computerized system security and password policy that defines security for access to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:673.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">computer systems managed and controlled by us, and a procedure for computerized system incident management to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">address any unplanned issues in regulated computerized systems that could impact subject safety, product quality, and data </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">integrity. We further protect access by monitoring risk-based sign-in attempts, and require stronger authentication (e.g., </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">multi-factor authentication) based on defined policies.  We periodically conduct cybersecurity incident tabletop training </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exercises involving our personnel and plan to continue conducting similar training exercises in 2026.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:45pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our assessment and management of material risks from cybersecurity threats are </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:446.36pt;position:var(--position);text-decoration:none;white-space:pre">integrated</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:486.29pt;position:var(--position);text-decoration:none;white-space:pre"> into our overall </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:57pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">risk management processes. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:172.81pt;position:var(--position);text-decoration:none;white-space:pre">For example, our </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:243.86pt;position:var(--position);text-decoration:none;white-space:pre">head of Information Technology</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:374.01pt;position:var(--position);text-decoration:none;white-space:pre"> evaluates material risks from cybersecurity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:69pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">threats and reports periodically to the Audit Committee of our Board, which evaluates our overall enterprise risk. We use </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:81pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">third-party</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:101.22999999999999pt;position:var(--position);text-decoration:none;white-space:pre"> service providers to assist us from time to time to identify, assess, and manage material risks from cybersecurity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:93pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">threats, including, for example, cybersecurity software providers such as our managed detection and response firm, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:105pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity service providers, penetration testing firms, auditors, and professional services firms, such as our virtual </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:117pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Chief Information Security Officer, including legal counsel. These relationships enable us to leverage specialized </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:129pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">knowledge and insights, enabling our cybersecurity strategies and processes to remain consistent with industry best </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:141pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">practices.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:165pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We rely on </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:168.39pt;position:var(--position);text-decoration:none;white-space:pre">third-party</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:211.12pt;position:var(--position);text-decoration:none;white-space:pre"> service providers to perform a variety of functions throughout our business, such as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:177pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">contract manufacturing organizations, contract research organizations, suppliers and consultants, and third party logistics </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:189pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">organizations and distributors to distribute RYTELO. We conduct quality and cyber audits of regulated vendors, which </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:201pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">typically include an assessment of such vendor’s information technology systems, checks for recent cybersecurity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:213pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">incidents, analyzing potential vulnerabilities associated with such vendor's externally facing infrastructure, and the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:225pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity controls they have in place to protect the Company's data, and we impose appropriate contractual obligations </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:237pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">on vendors pertaining to information security. Depending on the nature of the services provided, the sensitivity of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:249pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Information Systems and Data at issue, and the identity of the provider, our efforts may involve different levels of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:261pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">assessment designed to help identify cybersecurity risks associated with a provider and impose contractual obligations </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:273pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related to cybersecurity on the provider.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Depending on the environment, we implement and maintain various technical, physical, and organizational </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">measures, processes, standards and policies designed to manage and mitigate material risks from cybersecurity threats to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our Information Systems and Data. For example, in 2025, we expanded our monitoring capabilities by engaging with a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">managed detection and response firm to monitor and respond to security alerts on a 24-hour, seven-day-a-week basis.  We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:649.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have implemented and maintain an incident response plan, and we utilize automated tools designed to maintain email </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:661.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">security. We have also implemented a computerized system security and password policy that defines security for access to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:673.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">computer systems managed and controlled by us, and a procedure for computerized system incident management to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">address any unplanned issues in regulated computerized systems that could impact subject safety, product quality, and data </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">integrity. We further protect access by monitoring risk-based sign-in attempts, and require stronger authentication (e.g., </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">multi-factor authentication) based on defined policies.  We periodically conduct cybersecurity incident tabletop training </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exercises involving our personnel and plan to continue conducting similar training exercises in 2026.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our assessment and management of material risks from cybersecurity threats are </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:446.36pt;position:var(--position);text-decoration:none;white-space:pre">integrated</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:486.29pt;position:var(--position);text-decoration:none;white-space:pre"> into our overall </span>risk management processes. true true true true false <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Governance</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:369pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our Board of Directors addresses our cybersecurity risk management as part of its general oversight </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:381pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">function. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:96.8pt;position:var(--position);text-decoration:none;white-space:pre">The Audit Committee of our Board is responsible for overseeing our cybersecurity risk management processes, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:393pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">including oversight and mitigation of risks from cybersecurity threats.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:417pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our Audit Committee, as well as our Chief Financial Officer and other members of our executive </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:429pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">management as appropriate, receives periodic reports from our head of Information Technology concerning our significant </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:441pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity threats and risks and the processes we have implemented to address them.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:410.02pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:412.52pt;position:var(--position);text-decoration:none;white-space:pre">The Audit Committee also </span></div>receives various periodic presentations related to cybersecurity threats, risk and mitigation. <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:96.8pt;position:var(--position);text-decoration:none;white-space:pre">The Audit Committee of our Board is responsible for overseeing our cybersecurity risk management processes, </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:393pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">including oversight and mitigation of risks from cybersecurity threats.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our Audit Committee, as well as our Chief Financial Officer and other members of our executive </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:429pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">management as appropriate, receives periodic reports from our head of Information Technology concerning our significant </span></div><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity threats and risks and the processes we have implemented to address them.</span> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:412.52pt;position:var(--position);text-decoration:none;white-space:pre">The Audit Committee also </span>receives various periodic presentations related to cybersecurity threats, risk and mitigation. <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Risk Management Personnel</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:501pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our Information Technology personnel responsible for cybersecurity risk assessment and management </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:513pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">processes are managed by certain members of our executive management, including our Chief Financial Officer.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:509.03pt;position:var(--position);text-decoration:none;white-space:pre"> Together </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:525pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with our executive management, our Information Technology personnel are responsible for helping to integrate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:537pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity risk considerations into our overall risk management strategy, and communicating key priorities to relevant </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:549pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">personnel.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:99.85pt;position:var(--position);text-decoration:none;white-space:pre"> We believe these Information Technology personnel have the</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:348.43pt;position:var(--position);text-decoration:none;white-space:pre"> skills appropriate to help us prepare for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:561pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity incidents, approve cybersecurity processes, and review security assessments and other security-related </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:573pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reports.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:597pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our cybersecurity incident response plan is designed to escalate certain cybersecurity incidents to members </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:609pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of management depending on the circumstances, including executive management. When appropriate given the nature of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:621pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">any potential cybersecurity incident, our executive management works with our incident response team to help us mitigate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:633pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and remediate cybersecurity incidents of which they are notified, and to make any legally required notifications to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:645pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">individuals or regulatory agencies, including making any required disclosures under the Exchange Act.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our Information Technology personnel responsible for cybersecurity risk assessment and management </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:513pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">processes are managed by certain members of our executive management, including our Chief Financial Officer.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:509.03pt;position:var(--position);text-decoration:none;white-space:pre"> Together </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:525pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with our executive management, our Information Technology personnel are responsible for helping to integrate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:537pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cybersecurity risk considerations into our overall risk management strategy, and communicating key priorities to relevant </span></div><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">personnel.</span> true 42 Ernst & Young LLP Iselin, New Jersey 77560000 79016000 1880000 1860000 280359000 327550000 36987000 35946000 2239000 2853000 116636000 38714000 4610000 5053000 520271000 490992000 41289000 94519000 884000 1310000 2151000 2881000 5945000 4079000 570540000 593781000 11257000 8595000 30497000 22808000 1000000 974000 17448000 20372000 51340000 35549000 111542000 88298000 1445000 2266000 112134000 104421000 119547000 118476000 344668000 313461000 0.001 0.001 3000000 3000000 0 0 0 0 0 0 0.001 0.001 1350000000 1350000000 639856222 639856222 606387666 606387666 640000 606000 2080804000 2051794000 -1855841000 -1772341000 269000 261000 225872000 280320000 570540000 593781000 183623000 76495000 0 258000 499000 237000 4745000 1256000 0 71433000 103738000 125046000 159256000 145732000 69135000 17032000 0 0 252466000 250726000 194181000 -68585000 -173732000 -193944000 18117000 19607000 18152000 32657000 18504000 8312000 -375000 -236000 -23000 0 -1707000 0 -83500000 -174572000 -184127000 -0.13 -0.13 -0.27 -0.27 -0.32 -0.32 666662989 666662989 646033247 646033247 570645405 570645405 -83500000 -174572000 -184127000 -45000 88000 431000 53000 -12000 -27000 -83492000 -174496000 -183723000 390262524 390000 1493469000 -1413642000 -219000 79998000 -184127000 -184127000 431000 431000 -27000 -27000 14507000 68007741 68000 213269000 213337000 77349858 78000 105834000 105912000 36864 1000 828000 829000 9255228 8000 13062000 13070000 18526000 18526000 544912215 545000 1844988000 -1597769000 185000 247949000 -174572000 -174572000 88000 88000 -12000 -12000 9271000 41999998 42000 140687000 140729000 1071981 1000 1393000 1394000 8351 134000 134000 18395121 18000 32665000 32683000 31927000 31927000 606387666 606000 2051794000 -1772341000 261000 280320000 -83500000 -83500000 -45000 -45000 53000 53000 30369830 31000 1510000 1541000 22073 88000 88000 1162376 1511000 1511000 1275292 2000 1518000 1520000 26659000 26659000 638985 1000 746000 747000 639856222 640000 2080804000 -1855841000 269000 225872000 -83500000 -174572000 -184127000 474000 546000 442000 6921000 9683000 11150000 1071000 -3108000 1088000 18948000 5345000 0 0 -1707000 0 88000 135000 828000 26659000 31185000 18526000 730000 675000 591000 -50000 -251000 0 77922000 37971000 0 991000 35695000 0 -614000 1198000 -1490000 -443000 175000 886000 1865000 -618000 -692000 2661000 2435000 -4029000 7689000 9049000 2224000 14159000 2186000 0 15790000 -4759000 7208000 -796000 -715000 -640000 -111037000 -218618000 -167743000 49000 680000 830000 304421000 476932000 475594000 411717000 371608000 296102000 107247000 -106004000 -180322000 2267000 32683000 13072000 0 140729000 213337000 0 1394000 105912000 0 125000000 0 0 121120000 29700000 0 86554000 0 2267000 334372000 362021000 87000 -12000 -27000 -1436000 9738000 13929000 80876000 71138000 57209000 79440000 80876000 71138000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:109.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The terms “Geron”, the “Company”, “we” and “us” as used in this report refer to Geron Corporation, which </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">was incorporated in the State of Delaware on November 28, 1990, and its wholly-owned subsidiaries, Geron UK Limited, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">or Geron UK, a United Kingdom company, and Geron Netherlands B.V., or Geron Netherlands, a Netherlands company. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Geron UK was incorporated in September 2021, and its operations commenced in January 2022. Geron Netherlands was </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">incorporated in February 2023, and its operations commenced in June 2023. The Company's first-in-class telomerase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">inhibitor, RYTELO</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:137.31pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">TM</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:147.05pt;position:var(--position);text-decoration:none;white-space:pre"> (imetelstat), was approved by the U.S. Food and Drug Administration, or FDA, on June 6, 2024 for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the treatment of certain adult patients with low- to intermediate-1 risk myelodysplastic syndromes, or lower-risk MDS, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:193.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">is under development for the treatment of other hematologic malignancies. In March 2025, we received European </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:205.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Commission approval of RYTELO for the treatment of adults with </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:328.22pt;position:var(--position);text-decoration:none;white-space:pre">transfusion-dependent, or TD, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:451.17pt;position:var(--position);text-decoration:none;white-space:pre">anemia due to lower-risk </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">MDS. We are pursuing paths to make RYTELO available to eligible lower-risk MDS patients outside of the U.S. To enable </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:229.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">paid access to patients outside the U.S. through approved Named Patient Programs (NPPs), in 2025 we partnered with </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:241.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Tanner Pharma, a distributor with broad global reach to support patient access.  </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Principles of Consolidation</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:289.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The consolidated financial statements include the accounts Geron Corporation and its wholly-owned </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:301.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">subsidiaries, Geron UK and Geron Netherlands. We have eliminated intercompany accounts and transactions. We prepare </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the financial statements of Geron UK and Geron Netherlands using the local currency as the functional currency. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">translate the assets and liabilities of Geron UK and Geron Netherlands at rates of exchange at the balance sheet date and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">translate income and expense items at average monthly rates of exchange. Foreign currency translation adjustments are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">included in accumulated other comprehensive income (loss), a separate component of stockholders’ equity, on our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:391.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Use of Estimates</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The accompanying consolidated financial statements have been prepared in accordance with generally </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">accepted accounting principles in the United States, or U.S. GAAP. The preparation of financial statements in conformity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with U.S. GAAP requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:457.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenues and expenses during the reporting period. On an ongoing basis, we evaluate our estimates, including those related </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to accrued liabilities, revenue recognition, fair value of marketable securities, inventory valuation, operating leases, right-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of-use assets, lease liabilities, income taxes, stock-based compensation, and interest expense related to sale of future </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">royalties. We base our estimates on historical experience and on various other market specific and relevant assumptions </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">that we believe to be reasonable under the circumstances. Actual results could differ from those estimates.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Revenue Recognition</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Revenues are recognized when control of the promised goods or services is transferred to our customers, in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">an amount that reflects the consideration we expect to be entitled to in exchange for those goods or services. We recognize </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue in accordance with the provisions of Accounting Standards Codification Topic 606, Revenue from Contracts with </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Customers, or Topic 606. In determining the appropriate amount and timing of revenue to be recognized, we perform the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">following five steps: (i) identify the contract(s) with a customer; (ii) identify the performance obligations in the contract; </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(iii) measure the transaction price; (iv) allocate the transaction price to the performance obligations; and (v) recognize </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue when (or as) we satisfy each performance obligation. We recognize shipping and handling costs as an expense in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cost of goods sold when we transfer control to a customer. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:661.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Product Revenue</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We distribute RYTELO through third party distributors and specialty pharmacies who are our customers. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The third party distributors subsequently resell our product through their related specialty pharmacy providers to patients </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and health care providers. Separately, we have or may enter into payment arrangements with various third-party payors </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">including pharmacy benefit managers, private healthcare insurers and government healthcare programs who provide </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:733.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">coverage and reimbursement for our product that have been prescribed to a patient.</span></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product sales revenue is recognized when control has transferred to the customer, which occurs at a point in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">time, which is typically on delivery to the customer or, in the case of products that are subject to consignment agreements, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">when the customer removes product from our consigned inventory location for shipment directly to a patient. We expense </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">incremental costs of obtaining a contract as and when incurred if the expected amortization period of the asset that we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">would have recognized is one year or less or the amount is immaterial.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Reserves for Discounts and Allowances</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product revenue is recorded net of reserves established for applicable discounts and allowances that are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">offered within contracts with our customers, health care providers or payors.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">These reserves are based on estimates of the amounts earned or to be claimed on the related sales and are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">classified as reductions of accounts receivable (if the amount is payable to our customer) or a liability (if the amount is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">payable to a party other than our customer). Our estimates of reserves established for variable consideration are calculated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">based upon a consistent application of our methodology utilizing the expected value method. These estimates reflect our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">historical experience, current contractual and statutory requirements, specific known market events and trends, industry </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">data and forecasted customer buying and payment patterns. The transaction price, which includes variable consideration </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reflecting the impact of discounts and allowances, may be subject to constraint and is included in the net sales price only to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the extent that it is probable that a significant reversal of the amount of the cumulative revenue recognized will not occur in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">a future period. Actual amounts may ultimately differ from our estimates. If actual results vary, we adjust these estimates, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">which could have an effect on earnings in the period of adjustment.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product revenue reserves, which are classified as a reduction in product revenue, are generally </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">characterized in the following categories: contractual adjustments, discounts, and returns.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Contractual adjustments primarily relate to VA and PHS discounts, Medicaid and Medicare rebates, fees </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">for distribution services, co-payment (copay) assistance, and other governmental rebates or applicable allowances:</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Chargebacks, including VA and PHS discounts, represent our estimated obligations resulting from contractual </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">commitments to sell products to qualified healthcare providers at prices lower than the list prices we charge to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">wholesalers or distributors, which provide those products. The wholesalers or distributors charge us for the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:439.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">difference between what they pay for RYTELO and the ultimate selling price to the qualified healthcare providers. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Rebate and chargeback reserves are established in the same period as the related revenue is recognized, resulting </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">in a reduction of product revenue and a reduction in the net accounts receivable. Chargeback amounts are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">generally determined at the time of resale to the qualified healthcare provider from the wholesaler or distributor, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">and we generally issue credits for such amounts within a few weeks of the wholesaler notifying us about the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">resale. Our reserves for VA, PHS and other chargebacks consist of amounts for inventory that exists at the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">wholesalers that we expect will be sold to qualified healthcare providers and chargebacks that wholesalers have </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">claimed for which we have not issued a credit.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Medicaid rebates relate to our estimated obligations to states under established reimbursement arrangements. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Rebate accruals are recorded in the same period the related revenue is recognized, resulting in a reduction of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:571.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">product revenue and the establishment of a liability which is included in accrued expense and other current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">liabilities in our consolidated balance sheets. Our liability for Medicaid rebates consists of estimates for claims </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">that a state will make for the current quarter, claims for prior quarters that have been estimated for which an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">invoice has not been received, invoices received for claims from the prior quarters that have not been paid and an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">estimate of potential claims that will be made for inventory that exists in the distribution channel at period end.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Fees for distribution services include fees for certain data that customers provide to us. We estimate our customers </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">will earn these fees and deduct these fees from gross product revenue and accounts receivable at the time we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">recognize the related revenues.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Copay assistance represents financial assistance to qualified patients, assisting them with prescription drug co-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">payments required by insurance. The calculation of the accrual for copay is based on an estimate of claims and the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">cost per claim that we expect to receive associated with inventory that exists in the distribution channel at period </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:727.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">end.</span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Discounts primarily include  prompt pay discounts. Prompt pay discounts relate to estimated obligations for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credits to be granted to customers for remitting payment on their purchases within established incentive periods. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">determine these reserves based on our historical experience, including the timing of customer payments. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product return reserves are established for returns made by customers and are recorded in the period the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related revenue is recognized, resulting in a reduction to product revenue. We offer customers the right to return products if </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">they are damaged, defective, or expired, as defined in customer agreements.The majority of wholesaler returns are due to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">product expiration. We estimate product returns considering experience from similar products in the market, historical </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">return patterns, sales data, and inventory levels in the distribution channel</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:353.14pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value Measurements</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We categorize financial instruments recorded at fair value in our consolidated balance sheets based upon </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the level of judgment associated with inputs used to measure their fair value. The categories are as follows:</span></div><div style="position:var(--position);top:241.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:12pt"></td><td style="padding:0;width:36pt"></td><td style="padding:0;width:22.5pt"></td><td style="padding:0;width:424.5pt"></td></tr><tr style="height:51pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:12pt;position:var(--position);width:36pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:36pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Level 1</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:48pt;position:var(--position);width:22.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:22.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:9.87pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:70.5pt;position:var(--position);width:424.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Inputs are unadjusted, quoted prices in active markets for identical assets or liabilities at the </span></div><div style="line-height:10pt;position:var(--position);top:15.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">measurement date that we have the ability to access. An active market for the asset or liability is a </span></div><div style="line-height:10pt;position:var(--position);top:27.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">market in which transactions for the asset or liability occur with sufficient frequency and volume to </span></div><div style="line-height:10pt;position:var(--position);top:39.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">provide pricing information on an ongoing basis.</span></div></div></div></td></tr><tr style="height:6pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:39pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:12pt;position:var(--position);top:57pt;width:36pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:36pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Level 2</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:48pt;position:var(--position);top:57pt;width:22.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:22.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:9.87pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:70.5pt;position:var(--position);top:57pt;width:424.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Inputs (other than quoted market prices included in Level 1) are either directly or indirectly observable </span></div><div style="line-height:10pt;position:var(--position);top:15.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">for the asset or liability through correlation with market data at the measurement date and for the </span></div><div style="line-height:10pt;position:var(--position);top:27.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">duration of the instrument’s anticipated life.</span></div></div></div></td></tr><tr style="height:6pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:39pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:12pt;position:var(--position);top:102pt;width:36pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:36pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Level 3</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:48pt;position:var(--position);top:102pt;width:22.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:22.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:9.87pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:70.5pt;position:var(--position);top:102pt;width:424.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Inputs reflect management’s best estimate of what market participants would use in pricing the asset or </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">liability at the measurement date. Consideration is given to the risk inherent in the valuation technique </span></div><div style="line-height:10pt;position:var(--position);top:28.42pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">and the risk inherent in the inputs to the model.</span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:399.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">A financial instrument’s categorization within the valuation hierarchy is based upon the lowest level of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:411.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">input that is significant to the fair value measurement. Below is a description of the valuation methodologies used for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:423.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">financial instruments measured at fair value on our consolidated balance sheets, including the category for such financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:435.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">instruments.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:459.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The majority of our financial assets have been classified as Level 2, and have been initially valued at the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:471.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">transaction price and subsequently valued, at the end of each reporting period, utilizing third-party pricing services. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:483.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">pricing services utilize industry standard valuation models, including both income and market-based approaches and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:495.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">observable market inputs to determine value. These observable market inputs include reportable trades, benchmark yields, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:507.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit spreads, broker/dealer quotes, bids, offers, current spot rates and other industry and economic events.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:531.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We validate the prices provided by our third-party pricing services by understanding the models used, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:543.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">obtaining market values from other pricing sources and analyzing pricing data in certain instances. After completing our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:555.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">validation procedures, we did not adjust or override any fair value measurements provided by our pricing services as of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:567.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025 and 2024.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:591.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The carrying amounts reflected in our consolidated balance sheets for accounts receivable, other current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:603.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">assets, accounts payable, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:160.31pt;position:var(--position);text-decoration:none;white-space:pre">accrued compensation and benefits</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:300.4pt;position:var(--position);text-decoration:none;white-space:pre"> and accrued expense approximate fair value due to their short-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:615.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">term maturities.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:639.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash Equivalents</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:663.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We consider all highly liquid investments, readily convertible to cash and that mature within three months </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:675.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">or less from date of purchase to be cash equivalents. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:269.65pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2025 and 2024, cash equivalents were comprised </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:687.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of money market funds and commercial paper with maturities less than three months from the date of purchase.</span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Marketable Securities</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our marketable debt securities include U.S. Treasury securities, municipal securities, government-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">sponsored enterprise securities, commercial paper and corporate notes.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We classify our marketable debt securities as available for sale. We record available for sale debt securities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">at fair value with unrealized gains and losses reported in accumulated other comprehensive income (loss) in stockholders’ </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">equity, unless the security has experienced a credit loss, we have determined that we have the intent to sell the security or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">we have determined that it is more likely than not that we will have to sell the security before its expected recovery. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have not recorded any allowances for credit losses on our available-for-sale securities for the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:481.85pt;position:var(--position);text-decoration:none;white-space:pre">December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">,</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:81pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:83.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> or 2023. Realized gains and losses are reported in other (income) expense, net on a specific identification basis. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:193.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Dividend and interest income are recognized when earned and included in interest income on our consolidated statements </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:205.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of operations</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:110.95pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Restricted Cash</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Restricted cash consists of funds maintained in separate money market or certificate of deposit accounts for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:265.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit card purchases.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Accounts Receivable</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Accounts receivable consists of amounts due from customers, net of customer allowances for cash </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">discounts, product returns, and chargebacks. Accounts receivable are stated net of an allowance that reflects our current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">estimate of credit losses expected to occur over the life of the receivable. In developing our allowance for expected credit </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">losses, we use assumptions to capture the risk of loss, even if remote, based on a number of factors including existing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">contractual payment terms, individual customer circumstances, historical payment patterns of our customers, a review of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the local economic environment and its potential impact on expected future customer payment patterns. We update our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">allowance as necessary to reflect expected credit losses over the remaining lives of the accounts receivable for outstanding </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">trade receivables that are past due, have known disputes or have experienced any negative credit events that may result in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">future collectability issues. The estimated allowance for expected credit losses was not material as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:464.02pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:542.56pt;position:var(--position);text-decoration:none;white-space:pre">, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">nor were the changes to the allowance during any of the periods presented. We do not adjust our receivables for the effects </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of a significant financing component at contract inception if we expect to collect the receivables in one year or less from </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the time of sale.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Concentration of Credit Risk</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Financial instruments that potentially subject us to concentrations of credit risk include cash and cash </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">equivalents, restricted cash, marketable securities, and accounts receivable. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We currently place our cash, restricted cash, cash equivalents and marketable securities with multiple </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. We have not </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">experienced any losses in such accounts and we believe that we are not exposed to significant credit risk of our financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">position at the depository institutions, in which those deposits are held. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We attempt to minimize the risks related to cash equivalents and marketable securities by investing in a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">broad and diverse range of financial instruments as previously defined by us. We have established guidelines related to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit ratings and maturities intended to safeguard principal balances and maintain liquidity. Our investment portfolio is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">maintained in accordance with our investment policy, which defines allowable investments, specifies credit quality </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">standards and limits the credit exposure of any single issuer. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:301.85pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents and marketable securities currently consist of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">money market funds, U.S. Treasury securities, municipal securities, commercial paper and corporate notes. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Concentrations of credit risk with respect to receivables, which are typically unsecured, are somewhat </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">mitigated since t</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:124.5pt;position:var(--position);text-decoration:none;white-space:pre">he payment terms on our trade receivables are relatively short. As a result, our collection risk is mitigated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to a certain extent by the fact that sales are collected in a relatively short period of time, allowing for the ability to reduce </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exposure on defaults if collection issues are identified. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:278.5pt;position:var(--position);text-decoration:none;white-space:pre">We monitor the financial performance and creditworthiness of our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">customers so that we can properly assess and respond to changes in their credit profile. We continue to monitor these </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:727.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">conditions and assess their possible impact on our business.</span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Property and Equipment</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Property and equipment are carried at cost, subject to reviews for impairment whenever events or changes </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in circumstances indicate that the carrying amount of the asset may not be recoverable. The cost of normal, recurring or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">periodic repairs and maintenance activities related to property, plant and equipment are expensed as incurred. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We generally depreciate or amortize the cost of our property and equipment using the straight-line method </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">over the estimated useful lives of the respective assets</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:274.31pt;position:var(--position);text-decoration:none;white-space:pre">, generally </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:318.97pt;position:var(--position);text-decoration:none;white-space:pre">four years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:359.21pt;position:var(--position);text-decoration:none;white-space:pre">. Leasehold improvements are amortized over </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the shorter of the estimated useful life or remaining term of the lease.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Inventory</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We began capitalizing inventory related to RYTELO in the quarter ended June 30, 2024, as we received </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">approval of RYTELO on June 6, 2024, and the related costs were expected to be recoverable through the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">commercialization of RYTELO.  </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Inventory is recorded at the lower of cost or net realizable value, with cost determined </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:468.27pt;position:var(--position);text-decoration:none;white-space:pre">under the weighted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">average method</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.02000000000001pt;position:var(--position);text-decoration:none;white-space:pre">. Inventory costs include third-party contract manufacturing, third-party packaging services, freight, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">salaries, wages and stock-based compensation for personnel involved in the manufacturing process, and indirect overhead </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">costs. We periodically review our inventories to identify excess, obsolete, or slow moving items. If excess, obsolete, or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">slow moving inventory without an alternate use is identified, we adjust the recorded amount to its net realizable value. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">determination of net realizable value requires judgment including consideration of many factors, such as estimates of future </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">product demand, product net selling prices, current and future market conditions and potential product obsolescence, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">among others. Additionally, our products are subject to strict quality control and monitoring that we perform throughout </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:355.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the manufacturing process. In the event that certain batches or units of product no longer meet quality specifications, we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">will record a charge to cost of sales to write-down any unmarketable inventory to its estimated net realizable value. In all </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cases, product inventory is carried at the lower of cost or its estimated net realizable value. Amounts written-down due to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:391.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">unmarketable inventory are charged to cost of sales in our consolidated statements of operations.  </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Prior to regulatory approval, we expense costs associated with the manufacture of a product candidate to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">research and development expense unless we are reasonably certain such costs have future commercial use and net </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:439.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">realizable value. Since we consider attaining regulatory approval of a product candidate to be highly uncertain and difficult </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to predict, we expect only in rare instances that pre-launch inventory will be capitalized, if at all.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Assets that are expected to be realized in cash or consumed during the normal operating cycle are classified </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">as current. Due to the nature of pharmaceutical manufacturing, including production lead times, stability testing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">requirements, quality control procedures, and regulatory release processes, our operating cycle may exceed twelve months. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Inventory is held for sale or use within this normal operating cycle and is not held for long-term strategic purposes. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">classify all inventory as a current asset on the consolidated balance sheets.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:355.32pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Cost of Goods Sold</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cost of goods sold includes the cost of producing and distributing inventories that are related to product </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue during the respective period, including salary related and stock-based compensation expense for employees </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">involved with production and distribution, freight, and indirect overhead costs. Cost of goods sold may also include costs </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related to excess or obsolete inventory adjustment, abnormal costs, unabsorbed manufacturing and overhead costs, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">manufacturing variances. For the twelve months ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:280.47pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:359.01pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:398.44pt;position:var(--position);text-decoration:none;white-space:pre">, cost of sales related to product </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue was positively impacted since the weighted average cost of inventories sold included batches that were partially </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expensed prior to FDA approval.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Research and Development Expenses</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Research and development expenses consist of expenses incurred in developing and testing imetelstat and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">research related to potential next generation telomerase inhibitors. These expenses include, but are not limited to, payroll </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and personnel expense, lab supplies, non-clinical studies, clinical trials, including support for investigator-led clinical trials, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">raw materials to manufacture clinical trial drugs, manufacturing costs for research and clinical trial materials, sponsored </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:733.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">research at other labs, consulting, costs to maintain technology licenses and research-related overhead. Research and </span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">development expense is expensed as incurred. Payments we make for research and development services prior to the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">services being rendered are recorded as prepaid assets in our consolidated balance sheets and are expensed as the services </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">are provided. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our current RYTELO (imetelstat) clinical trials are being supported by contract research organizations, or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">CROs, and other vendors. We accrue expenses for clinical trial activities performed and managed by CROs based upon the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">amount of work completed on each trial. Expenses are recorded based on contracted amounts agreed to with our CROs and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">through monthly reporting provided by CROs. We monitor activities conducted and managed by the CROs to the extent </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">possible through internal reviews, review of contractual terms and correspondence with CROs. We record expense on the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">best information available at the time. However, additional information may become available to us which may require us </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to record adjustments to research and development expenses in future periods.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Selling, General and Administrative Expense</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:241.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Selling, general and administrative expense is primarily comprised of compensation and benefits associated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with sales and marketing, finance, human resources, legal, information technology and other administrative personnel, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:265.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">outside marketing, advertising and legal expense and other general and administrative costs.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:289.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring Charges</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring charges consist of termination benefits such as </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:366.77pt;position:var(--position);text-decoration:none;white-space:pre">one-time employee severance payments, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">healthcare and related benefits, and other employee-related costs</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:316.99pt;position:var(--position);text-decoration:none;white-space:pre">. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:321.99pt;position:var(--position);text-decoration:none;white-space:pre">We accrue severance and other related restructuring costs </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">when it is probable that they will be paid and the amount is reasonably estimable. Restructuring costs are recorded in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">restructuring charges in the consolidated statements of operations. The related restructuring liability is included in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:516.24pt;position:var(--position);text-decoration:none;white-space:pre">accrued </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">compensation and benefits</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:165.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre"> in the consolidated balance sheet.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock‑Based Compensation</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We maintain various stock incentive plans under which stock options, restricted stock units and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:505.8pt;position:var(--position);text-decoration:none;white-space:pre">restricted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock awards</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:110.39pt;position:var(--position);text-decoration:none;white-space:pre"> can be granted to employees, non-employee directors and consultants. We also have an employee stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">purchase plan for all eligible employees. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For service based options, restricted stock award and restricted stock units, compensation expense is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recognized based on the estimated fair value of the awards at grant date. We recognize compensation expense on a straight-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">line basis, after taking into consideration an estimate of forfeitures, over the requisite service period, which is generally the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">vesting period.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For performance-based stock options with vesting based on the achievement of certain strategic milestones, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock-based compensation expense is recognized over the period from the date the performance condition is determined to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">be probable of occurring through the date the applicable condition is expected to be met and is reduced for estimated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">forfeitures, as applicable. If the performance condition is not considered probable of being achieved, no stock-based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">compensation expense is recognized until such time as the performance condition is considered probable of being met, if at </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:571.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">all. If the assessment of probability of the performance condition changes, the impact of the change in estimate would be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recognized in the period of the change. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The grant-date fair value for service-based restricted stock units or restricted stock awards is determined </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">using the fair value of our common stock on the date of grant. The determination of grant-date fair values for our service-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">based and performance-based stock options and employee stock purchases using the Black-Scholes option pricing model is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">affected by our stock price as well as assumptions regarding a number of complex and subjective variables. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Dividend yield is based on historical cash dividend payments and we have paid no cash dividends to date. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The expected volatility range is based on historical volatilities of our stock, since traded options on our common stock do </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">not correspond to option terms and the trading volume of options is limited. The risk‑free interest rate range is based on the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Zero Coupon Treasury Strip Yields for the expected term in effect on the date of grant for an award. The expected </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">term of stock options is derived from actual historical exercise and post‑vesting cancellation data and represents the period </span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of time that stock options granted are expected to be outstanding. The expected term of employees’ purchase rights is equal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to the purchase period.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We grant stock options to consultants from time to time in exchange for services performed for us. In </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">general, these stock options vest over the contractual period of the consulting arrangement. The fair value of stock options </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">held by consultants is recorded as operating expenses over the vesting term of the respective equity awards. With the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">adoption of Accounting Standards Update 2018-07, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:267.51pt;position:var(--position);text-decoration:none;white-space:pre">Improvements to Nonemployee Share-Based Payment Accounting</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:530.28pt;position:var(--position);text-decoration:none;white-space:pre">, the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">measurement date of stock options granted to consultants was fixed at the grant date.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Net Loss Per Share</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Basic net income (loss) per share is calculated by dividing net income (loss) by the weighted-average </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">number of shares of common stock outstanding for the periods presented without consideration of potential common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">shares. In connection with previous public offerings, we issued pre-funded warrants to purchase shares of our common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Diluted net income per share would be calculated by adjusting the weighted-average number of shares of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common stock outstanding for the dilutive effect of additional shares of common stock that would have been outstanding if </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">potentially dilutive securities had been issued, as determined using the treasury-stock method. Potential dilutive securities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consist of outstanding stock options and warrants to purchase our common stock. Diluted net loss per share excludes </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">potential dilutive securities for all periods presented as their effect would be anti-dilutive. Accordingly, basic and diluted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">net loss per share is the same for all periods presented in the accompanying consolidated statements of operations. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Leases</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">At the inception of an arrangement, we determine whether the arrangement is or contains a lease based on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the unique facts and circumstances present. Operating leases are included in operating leases, right-of-use assets and lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">liabilities on our consolidated balance sheets. Right-of-use assets represent our right to use an underlying asset for the lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">term and lease liabilities represent our obligation to make lease payments arising from the lease. Operating lease liabilities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and their corresponding right-of-use assets are recorded based on the present value of remaining lease payments over the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expected lease term. The present value of remaining lease payments within the 12 months following the balance sheet date </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">are classified as current lease liabilities. The present value of lease payments not within the 12 months following the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">balance sheet date are classified as noncurrent lease liabilities. The interest rate implicit in lease contracts is typically not </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:457.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">readily determinable. As such, to calculate the net present value of lease payments, we apply our incremental borrowing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">rate, which is the estimated rate to borrow on a collateralized basis over a similar term an amount equal to the lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">payments in a similar economic environment as of the lease commencement date. We may adjust the right-of-use assets for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">certain adjustments, such as initial direct costs paid or incentives received. In addition, we include any options to extend or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">terminate the lease in the expected lease term when it is reasonably certain that we will exercise any such option. Lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:517.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expense is recognized on a straight-line basis over the expected lease term.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:541.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For lease agreements that include lease and non-lease components, such components are generally </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">accounted for separately. We have also elected not to recognize on our consolidated balance sheets leases with terms of one </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">year or less.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Royalty Pharma Agreement Interest Expense </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The liability related to the Royalty Pharma Agreement and the related interest expense are measured based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">on our current estimate of the timing and amount of expected future Royalty Payments expected to be paid over the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">estimated term of the Royalty Pharma Agreement using a discounted cash flow model. The liability is amortized using the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">effective interest rate method, resulting in recognition of non-cash interest expense over the estimated term of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">agreement. Each reporting period, we assess the estimated timing and amount of future expected Royalty Payments over </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the estimated term. If there are changes to the estimate, we recognize the impact to the liability’s amortization schedule and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the related non-cash interest expense prospectively. Additionally, the transaction costs associated with the liability are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">amortized to non-cash interest expense over the estimated term of the Royalty Pharma Agreement.</span></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Income Taxes</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We maintain deferred tax assets and liabilities that reflect the net tax effects of temporary differences </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:109.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">purposes and are subject to tests of recoverability. Our deferred tax assets include net operating loss carryforwards, federal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and state tax credits and capitalized research and development. Deferred tax assets and liabilities are measured using </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recovered or settled. Our net deferred tax asset has been fully offset by a valuation allowance because of our history of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">losses. Any potential accrued interest and penalties related to unrecognized tax benefits would be recorded as income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expense.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Segment Information</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our chief executive officer represents our chief operating decision maker. We view our operations as a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:229.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">single segment, the development of therapeutic products for oncology. As a result, the financial information disclosed </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:241.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">herein materially represents all of the financial information related to our principal operating segment. For additional </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">information, see Note 15 on Segment Reporting.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Recent Accounting Pronouncements</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:301.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">New Accounting Pronouncements – Issued But Not Yet Adopted</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In November 2024, the Financial Standards Accounting Board (FASB) issued Accounting Standards </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Update (ASU)  2024-03, Income Statement - Reporting Comprehensive Income - Expense Disaggregation Disclosures </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(Subtopic 220-40): Disaggregation of Income Statement Expenses. The amendments in ASU 2024-03 address investor </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:355.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">requests for more detailed expense information and require additional disaggregated disclosures in the notes to financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements for certain categories of expenses that are included on the face of the income statement. This guidance is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">effective for fiscal years beginning after December 15, 2026, and interim periods within fiscal years beginning after </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:391.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 15, 2027, with early adoption permitted. We are evaluating the impact of this ASU on our consolidated financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">New Accounting Pronouncements – Issued and Adopted</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">December 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:195.87pt;position:var(--position);text-decoration:none;white-space:pre">, the FASB issued ASU 2023-09, Income Taxes (ASU 2023-09), which requires issuers </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to make additional discloses on an annual basis related to specific categories in the rate reconciliation and provide </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">additional information for reconciling items that meet a quantitative threshold on an annual basis, disclose additional </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">information about income taxes paid as well as other disaggregated disclosures. ASU 2023-09 is effective for the Company </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">as of January 1, 2025 for annual periods. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:223.94pt;position:var(--position);text-decoration:none;white-space:pre">We adopted this standard and applied the disclosure requirements on a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">prospective basis effective for the year ended December 31, 2025. The adoption did not have a material impact on our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consolidated financial position or results of operations. Refer to Note 13, Income Taxes, for our updated income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">disclosure.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In November 2023, the FASB issued ASU 2023-07, Segment Reporting (ASU 2023-07), which requires </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">issuers to make additional disclosures with respect to segment expenses, including required disclosure on an annual and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">interim basis for significant segment expenses and other segment items. The improved disclosure requirements apply to all </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">public entities that are required to report segment information, including those with only </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.2pt;position:var(--position);text-decoration:none;white-space:pre">one</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:428.63pt;position:var(--position);text-decoration:none;white-space:pre"> reportable segment. ASU </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2023-07 also permits the disclosure of more than one measure of a segment’s profit or loss. ASU 2023-07 is effective for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the Company as of January 1, 2024 for annual periods and as of January 1, 2025 for interim periods. We adopted the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">guidance in the annual period ended December 31, 2024. There was no impact on our reportable segments identified and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">additional required disclosures have been included i</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:266.02pt;position:var(--position);text-decoration:none;white-space:pre">n Note 15. We view our operations as a single segment. See Note 15 on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:649.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Segment Reporting.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:673.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Other recent accounting pronouncements issued by the FASB did not or are not believed by management to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have a material impact on our financial statements.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The terms “Geron”, the “Company”, “we” and “us” as used in this report refer to Geron Corporation, which </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">was incorporated in the State of Delaware on November 28, 1990, and its wholly-owned subsidiaries, Geron UK Limited, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">or Geron UK, a United Kingdom company, and Geron Netherlands B.V., or Geron Netherlands, a Netherlands company. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Geron UK was incorporated in September 2021, and its operations commenced in January 2022. Geron Netherlands was </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">incorporated in February 2023, and its operations commenced in June 2023. The Company's first-in-class telomerase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">inhibitor, RYTELO</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:137.31pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">TM</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:147.05pt;position:var(--position);text-decoration:none;white-space:pre"> (imetelstat), was approved by the U.S. Food and Drug Administration, or FDA, on June 6, 2024 for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the treatment of certain adult patients with low- to intermediate-1 risk myelodysplastic syndromes, or lower-risk MDS, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:193.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">is under development for the treatment of other hematologic malignancies. In March 2025, we received European </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:205.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Commission approval of RYTELO for the treatment of adults with </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:328.22pt;position:var(--position);text-decoration:none;white-space:pre">transfusion-dependent, or TD, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:451.17pt;position:var(--position);text-decoration:none;white-space:pre">anemia due to lower-risk </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">MDS. We are pursuing paths to make RYTELO available to eligible lower-risk MDS patients outside of the U.S. To enable </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:229.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">paid access to patients outside the U.S. through approved Named Patient Programs (NPPs), in 2025 we partnered with </span></div>Tanner Pharma, a distributor with broad global reach to support patient access. <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Principles of Consolidation</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:289.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The consolidated financial statements include the accounts Geron Corporation and its wholly-owned </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:301.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">subsidiaries, Geron UK and Geron Netherlands. We have eliminated intercompany accounts and transactions. We prepare </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the financial statements of Geron UK and Geron Netherlands using the local currency as the functional currency. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">translate the assets and liabilities of Geron UK and Geron Netherlands at rates of exchange at the balance sheet date and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">translate income and expense items at average monthly rates of exchange. Foreign currency translation adjustments are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">included in accumulated other comprehensive income (loss), a separate component of stockholders’ equity, on our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consolidated balance sheets.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Use of Estimates</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The accompanying consolidated financial statements have been prepared in accordance with generally </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">accepted accounting principles in the United States, or U.S. GAAP. The preparation of financial statements in conformity </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with U.S. GAAP requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:457.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenues and expenses during the reporting period. On an ongoing basis, we evaluate our estimates, including those related </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to accrued liabilities, revenue recognition, fair value of marketable securities, inventory valuation, operating leases, right-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of-use assets, lease liabilities, income taxes, stock-based compensation, and interest expense related to sale of future </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">royalties. We base our estimates on historical experience and on various other market specific and relevant assumptions </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">that we believe to be reasonable under the circumstances. Actual results could differ from those estimates.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Revenue Recognition</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Revenues are recognized when control of the promised goods or services is transferred to our customers, in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">an amount that reflects the consideration we expect to be entitled to in exchange for those goods or services. We recognize </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue in accordance with the provisions of Accounting Standards Codification Topic 606, Revenue from Contracts with </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Customers, or Topic 606. In determining the appropriate amount and timing of revenue to be recognized, we perform the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">following five steps: (i) identify the contract(s) with a customer; (ii) identify the performance obligations in the contract; </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(iii) measure the transaction price; (iv) allocate the transaction price to the performance obligations; and (v) recognize </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue when (or as) we satisfy each performance obligation. We recognize shipping and handling costs as an expense in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cost of goods sold when we transfer control to a customer. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:661.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Product Revenue</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We distribute RYTELO through third party distributors and specialty pharmacies who are our customers. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The third party distributors subsequently resell our product through their related specialty pharmacy providers to patients </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and health care providers. Separately, we have or may enter into payment arrangements with various third-party payors </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">including pharmacy benefit managers, private healthcare insurers and government healthcare programs who provide </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:733.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">coverage and reimbursement for our product that have been prescribed to a patient.</span></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product sales revenue is recognized when control has transferred to the customer, which occurs at a point in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">time, which is typically on delivery to the customer or, in the case of products that are subject to consignment agreements, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">when the customer removes product from our consigned inventory location for shipment directly to a patient. We expense </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">incremental costs of obtaining a contract as and when incurred if the expected amortization period of the asset that we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">would have recognized is one year or less or the amount is immaterial.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Reserves for Discounts and Allowances</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product revenue is recorded net of reserves established for applicable discounts and allowances that are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">offered within contracts with our customers, health care providers or payors.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">These reserves are based on estimates of the amounts earned or to be claimed on the related sales and are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">classified as reductions of accounts receivable (if the amount is payable to our customer) or a liability (if the amount is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">payable to a party other than our customer). Our estimates of reserves established for variable consideration are calculated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">based upon a consistent application of our methodology utilizing the expected value method. These estimates reflect our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">historical experience, current contractual and statutory requirements, specific known market events and trends, industry </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">data and forecasted customer buying and payment patterns. The transaction price, which includes variable consideration </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reflecting the impact of discounts and allowances, may be subject to constraint and is included in the net sales price only to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the extent that it is probable that a significant reversal of the amount of the cumulative revenue recognized will not occur in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">a future period. Actual amounts may ultimately differ from our estimates. If actual results vary, we adjust these estimates, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">which could have an effect on earnings in the period of adjustment.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product revenue reserves, which are classified as a reduction in product revenue, are generally </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">characterized in the following categories: contractual adjustments, discounts, and returns.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Contractual adjustments primarily relate to VA and PHS discounts, Medicaid and Medicare rebates, fees </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">for distribution services, co-payment (copay) assistance, and other governmental rebates or applicable allowances:</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Chargebacks, including VA and PHS discounts, represent our estimated obligations resulting from contractual </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">commitments to sell products to qualified healthcare providers at prices lower than the list prices we charge to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">wholesalers or distributors, which provide those products. The wholesalers or distributors charge us for the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:439.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">difference between what they pay for RYTELO and the ultimate selling price to the qualified healthcare providers. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Rebate and chargeback reserves are established in the same period as the related revenue is recognized, resulting </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">in a reduction of product revenue and a reduction in the net accounts receivable. Chargeback amounts are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">generally determined at the time of resale to the qualified healthcare provider from the wholesaler or distributor, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">and we generally issue credits for such amounts within a few weeks of the wholesaler notifying us about the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">resale. Our reserves for VA, PHS and other chargebacks consist of amounts for inventory that exists at the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">wholesalers that we expect will be sold to qualified healthcare providers and chargebacks that wholesalers have </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">claimed for which we have not issued a credit.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Medicaid rebates relate to our estimated obligations to states under established reimbursement arrangements. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Rebate accruals are recorded in the same period the related revenue is recognized, resulting in a reduction of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:571.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">product revenue and the establishment of a liability which is included in accrued expense and other current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">liabilities in our consolidated balance sheets. Our liability for Medicaid rebates consists of estimates for claims </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">that a state will make for the current quarter, claims for prior quarters that have been estimated for which an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">invoice has not been received, invoices received for claims from the prior quarters that have not been paid and an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">estimate of potential claims that will be made for inventory that exists in the distribution channel at period end.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Fees for distribution services include fees for certain data that customers provide to us. We estimate our customers </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">will earn these fees and deduct these fees from gross product revenue and accounts receivable at the time we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">recognize the related revenues.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Copay assistance represents financial assistance to qualified patients, assisting them with prescription drug co-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">payments required by insurance. The calculation of the accrual for copay is based on an estimate of claims and the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">cost per claim that we expect to receive associated with inventory that exists in the distribution channel at period </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:727.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">end.</span></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Discounts primarily include  prompt pay discounts. Prompt pay discounts relate to estimated obligations for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credits to be granted to customers for remitting payment on their purchases within established incentive periods. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">determine these reserves based on our historical experience, including the timing of customer payments. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Product return reserves are established for returns made by customers and are recorded in the period the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related revenue is recognized, resulting in a reduction to product revenue. We offer customers the right to return products if </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">they are damaged, defective, or expired, as defined in customer agreements.The majority of wholesaler returns are due to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">product expiration. We estimate product returns considering experience from similar products in the market, historical </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">return patterns, sales data, and inventory levels in the distribution channel</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:353.14pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value Measurements</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We categorize financial instruments recorded at fair value in our consolidated balance sheets based upon </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the level of judgment associated with inputs used to measure their fair value. The categories are as follows:</span></div><div style="position:var(--position);top:241.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:12pt"></td><td style="padding:0;width:36pt"></td><td style="padding:0;width:22.5pt"></td><td style="padding:0;width:424.5pt"></td></tr><tr style="height:51pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:12pt;position:var(--position);width:36pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:36pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Level 1</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:48pt;position:var(--position);width:22.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:22.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:9.87pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:70.5pt;position:var(--position);width:424.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Inputs are unadjusted, quoted prices in active markets for identical assets or liabilities at the </span></div><div style="line-height:10pt;position:var(--position);top:15.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">measurement date that we have the ability to access. An active market for the asset or liability is a </span></div><div style="line-height:10pt;position:var(--position);top:27.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">market in which transactions for the asset or liability occur with sufficient frequency and volume to </span></div><div style="line-height:10pt;position:var(--position);top:39.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">provide pricing information on an ongoing basis.</span></div></div></div></td></tr><tr style="height:6pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:39pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:12pt;position:var(--position);top:57pt;width:36pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:36pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Level 2</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:48pt;position:var(--position);top:57pt;width:22.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:22.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:9.87pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:70.5pt;position:var(--position);top:57pt;width:424.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Inputs (other than quoted market prices included in Level 1) are either directly or indirectly observable </span></div><div style="line-height:10pt;position:var(--position);top:15.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">for the asset or liability through correlation with market data at the measurement date and for the </span></div><div style="line-height:10pt;position:var(--position);top:27.75pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">duration of the instrument’s anticipated life.</span></div></div></div></td></tr><tr style="height:6pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:39pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:12pt;position:var(--position);top:102pt;width:36pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:36pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Level 3</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:48pt;position:var(--position);top:102pt;width:22.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:22.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:9.87pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:70.5pt;position:var(--position);top:102pt;width:424.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Inputs reflect management’s best estimate of what market participants would use in pricing the asset or </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">liability at the measurement date. Consideration is given to the risk inherent in the valuation technique </span></div><div style="line-height:10pt;position:var(--position);top:28.42pt;width:424.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">and the risk inherent in the inputs to the model.</span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:399.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">A financial instrument’s categorization within the valuation hierarchy is based upon the lowest level of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:411.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">input that is significant to the fair value measurement. Below is a description of the valuation methodologies used for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:423.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">financial instruments measured at fair value on our consolidated balance sheets, including the category for such financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:435.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">instruments.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:459.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The majority of our financial assets have been classified as Level 2, and have been initially valued at the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:471.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">transaction price and subsequently valued, at the end of each reporting period, utilizing third-party pricing services. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:483.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">pricing services utilize industry standard valuation models, including both income and market-based approaches and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:495.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">observable market inputs to determine value. These observable market inputs include reportable trades, benchmark yields, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:507.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit spreads, broker/dealer quotes, bids, offers, current spot rates and other industry and economic events.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:531.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We validate the prices provided by our third-party pricing services by understanding the models used, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:543.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">obtaining market values from other pricing sources and analyzing pricing data in certain instances. After completing our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:555.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">validation procedures, we did not adjust or override any fair value measurements provided by our pricing services as of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:567.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025 and 2024.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:591.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The carrying amounts reflected in our consolidated balance sheets for accounts receivable, other current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:603.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">assets, accounts payable, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:160.31pt;position:var(--position);text-decoration:none;white-space:pre">accrued compensation and benefits</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:300.4pt;position:var(--position);text-decoration:none;white-space:pre"> and accrued expense approximate fair value due to their short-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:615.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">term maturities.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash Equivalents</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:663.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We consider all highly liquid investments, readily convertible to cash and that mature within three months </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:675.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">or less from date of purchase to be cash equivalents. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:269.65pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2025 and 2024, cash equivalents were comprised </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:687.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of money market funds and commercial paper with maturities less than three months from the date of purchase.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Marketable Securities</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our marketable debt securities include U.S. Treasury securities, municipal securities, government-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">sponsored enterprise securities, commercial paper and corporate notes.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We classify our marketable debt securities as available for sale. We record available for sale debt securities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">at fair value with unrealized gains and losses reported in accumulated other comprehensive income (loss) in stockholders’ </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">equity, unless the security has experienced a credit loss, we have determined that we have the intent to sell the security or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">we have determined that it is more likely than not that we will have to sell the security before its expected recovery. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have not recorded any allowances for credit losses on our available-for-sale securities for the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:481.85pt;position:var(--position);text-decoration:none;white-space:pre">December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">,</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:81pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:83.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> or 2023. Realized gains and losses are reported in other (income) expense, net on a specific identification basis. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:193.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Dividend and interest income are recognized when earned and included in interest income on our consolidated statements </span></div><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of operations</span> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Restricted Cash</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Restricted cash consists of funds maintained in separate money market or certificate of deposit accounts for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:265.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit card purchases.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Accounts Receivable</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Accounts receivable consists of amounts due from customers, net of customer allowances for cash </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">discounts, product returns, and chargebacks. Accounts receivable are stated net of an allowance that reflects our current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">estimate of credit losses expected to occur over the life of the receivable. In developing our allowance for expected credit </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">losses, we use assumptions to capture the risk of loss, even if remote, based on a number of factors including existing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">contractual payment terms, individual customer circumstances, historical payment patterns of our customers, a review of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the local economic environment and its potential impact on expected future customer payment patterns. We update our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">allowance as necessary to reflect expected credit losses over the remaining lives of the accounts receivable for outstanding </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">trade receivables that are past due, have known disputes or have experienced any negative credit events that may result in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">future collectability issues. The estimated allowance for expected credit losses was not material as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:464.02pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:542.56pt;position:var(--position);text-decoration:none;white-space:pre">, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">nor were the changes to the allowance during any of the periods presented. We do not adjust our receivables for the effects </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of a significant financing component at contract inception if we expect to collect the receivables in one year or less from </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the time of sale.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Concentration of Credit Risk</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Financial instruments that potentially subject us to concentrations of credit risk include cash and cash </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">equivalents, restricted cash, marketable securities, and accounts receivable. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We currently place our cash, restricted cash, cash equivalents and marketable securities with multiple </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. We have not </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">experienced any losses in such accounts and we believe that we are not exposed to significant credit risk of our financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">position at the depository institutions, in which those deposits are held. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We attempt to minimize the risks related to cash equivalents and marketable securities by investing in a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">broad and diverse range of financial instruments as previously defined by us. We have established guidelines related to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit ratings and maturities intended to safeguard principal balances and maintain liquidity. Our investment portfolio is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">maintained in accordance with our investment policy, which defines allowable investments, specifies credit quality </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">standards and limits the credit exposure of any single issuer. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:301.85pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents and marketable securities currently consist of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">money market funds, U.S. Treasury securities, municipal securities, commercial paper and corporate notes. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Concentrations of credit risk with respect to receivables, which are typically unsecured, are somewhat </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">mitigated since t</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:124.5pt;position:var(--position);text-decoration:none;white-space:pre">he payment terms on our trade receivables are relatively short. As a result, our collection risk is mitigated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to a certain extent by the fact that sales are collected in a relatively short period of time, allowing for the ability to reduce </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exposure on defaults if collection issues are identified. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:278.5pt;position:var(--position);text-decoration:none;white-space:pre">We monitor the financial performance and creditworthiness of our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">customers so that we can properly assess and respond to changes in their credit profile. We continue to monitor these </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:727.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">conditions and assess their possible impact on our business.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Property and Equipment</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Property and equipment are carried at cost, subject to reviews for impairment whenever events or changes </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in circumstances indicate that the carrying amount of the asset may not be recoverable. The cost of normal, recurring or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">periodic repairs and maintenance activities related to property, plant and equipment are expensed as incurred. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We generally depreciate or amortize the cost of our property and equipment using the straight-line method </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">over the estimated useful lives of the respective assets</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:274.31pt;position:var(--position);text-decoration:none;white-space:pre">, generally </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:318.97pt;position:var(--position);text-decoration:none;white-space:pre">four years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:359.21pt;position:var(--position);text-decoration:none;white-space:pre">. Leasehold improvements are amortized over </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the shorter of the estimated useful life or remaining term of the lease.</span></div> P4Y <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Inventory</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We began capitalizing inventory related to RYTELO in the quarter ended June 30, 2024, as we received </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">approval of RYTELO on June 6, 2024, and the related costs were expected to be recoverable through the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">commercialization of RYTELO.  </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Inventory is recorded at the lower of cost or net realizable value, with cost determined </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:468.27pt;position:var(--position);text-decoration:none;white-space:pre">under the weighted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">average method</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.02000000000001pt;position:var(--position);text-decoration:none;white-space:pre">. Inventory costs include third-party contract manufacturing, third-party packaging services, freight, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">salaries, wages and stock-based compensation for personnel involved in the manufacturing process, and indirect overhead </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">costs. We periodically review our inventories to identify excess, obsolete, or slow moving items. If excess, obsolete, or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">slow moving inventory without an alternate use is identified, we adjust the recorded amount to its net realizable value. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">determination of net realizable value requires judgment including consideration of many factors, such as estimates of future </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">product demand, product net selling prices, current and future market conditions and potential product obsolescence, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">among others. Additionally, our products are subject to strict quality control and monitoring that we perform throughout </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:355.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the manufacturing process. In the event that certain batches or units of product no longer meet quality specifications, we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">will record a charge to cost of sales to write-down any unmarketable inventory to its estimated net realizable value. In all </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cases, product inventory is carried at the lower of cost or its estimated net realizable value. Amounts written-down due to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:391.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">unmarketable inventory are charged to cost of sales in our consolidated statements of operations.  </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Prior to regulatory approval, we expense costs associated with the manufacture of a product candidate to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">research and development expense unless we are reasonably certain such costs have future commercial use and net </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:439.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">realizable value. Since we consider attaining regulatory approval of a product candidate to be highly uncertain and difficult </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to predict, we expect only in rare instances that pre-launch inventory will be capitalized, if at all.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Assets that are expected to be realized in cash or consumed during the normal operating cycle are classified </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">as current. Due to the nature of pharmaceutical manufacturing, including production lead times, stability testing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">requirements, quality control procedures, and regulatory release processes, our operating cycle may exceed twelve months. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Inventory is held for sale or use within this normal operating cycle and is not held for long-term strategic purposes. We </span></div><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">classify all inventory as a current asset on the consolidated balance sheets.</span> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Cost of Goods Sold</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cost of goods sold includes the cost of producing and distributing inventories that are related to product </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue during the respective period, including salary related and stock-based compensation expense for employees </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">involved with production and distribution, freight, and indirect overhead costs. Cost of goods sold may also include costs </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related to excess or obsolete inventory adjustment, abnormal costs, unabsorbed manufacturing and overhead costs, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">manufacturing variances. For the twelve months ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:280.47pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:359.01pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:398.44pt;position:var(--position);text-decoration:none;white-space:pre">, cost of sales related to product </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue was positively impacted since the weighted average cost of inventories sold included batches that were partially </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expensed prior to FDA approval.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Research and Development Expenses</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Research and development expenses consist of expenses incurred in developing and testing imetelstat and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">research related to potential next generation telomerase inhibitors. These expenses include, but are not limited to, payroll </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and personnel expense, lab supplies, non-clinical studies, clinical trials, including support for investigator-led clinical trials, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">raw materials to manufacture clinical trial drugs, manufacturing costs for research and clinical trial materials, sponsored </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:733.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">research at other labs, consulting, costs to maintain technology licenses and research-related overhead. Research and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">development expense is expensed as incurred. Payments we make for research and development services prior to the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">services being rendered are recorded as prepaid assets in our consolidated balance sheets and are expensed as the services </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">are provided. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our current RYTELO (imetelstat) clinical trials are being supported by contract research organizations, or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">CROs, and other vendors. We accrue expenses for clinical trial activities performed and managed by CROs based upon the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">amount of work completed on each trial. Expenses are recorded based on contracted amounts agreed to with our CROs and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">through monthly reporting provided by CROs. We monitor activities conducted and managed by the CROs to the extent </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">possible through internal reviews, review of contractual terms and correspondence with CROs. We record expense on the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">best information available at the time. However, additional information may become available to us which may require us </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to record adjustments to research and development expenses in future periods.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Selling, General and Administrative Expense</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:241.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Selling, general and administrative expense is primarily comprised of compensation and benefits associated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with sales and marketing, finance, human resources, legal, information technology and other administrative personnel, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:265.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">outside marketing, advertising and legal expense and other general and administrative costs.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring Charges</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring charges consist of termination benefits such as </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:366.77pt;position:var(--position);text-decoration:none;white-space:pre">one-time employee severance payments, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">healthcare and related benefits, and other employee-related costs</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:316.99pt;position:var(--position);text-decoration:none;white-space:pre">. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:321.99pt;position:var(--position);text-decoration:none;white-space:pre">We accrue severance and other related restructuring costs </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">when it is probable that they will be paid and the amount is reasonably estimable. Restructuring costs are recorded in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">restructuring charges in the consolidated statements of operations. The related restructuring liability is included in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:516.24pt;position:var(--position);text-decoration:none;white-space:pre">accrued </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">compensation and benefits</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:165.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre"> in the consolidated balance sheet.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock‑Based Compensation</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We maintain various stock incentive plans under which stock options, restricted stock units and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:505.8pt;position:var(--position);text-decoration:none;white-space:pre">restricted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock awards</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:110.39pt;position:var(--position);text-decoration:none;white-space:pre"> can be granted to employees, non-employee directors and consultants. We also have an employee stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">purchase plan for all eligible employees. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For service based options, restricted stock award and restricted stock units, compensation expense is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recognized based on the estimated fair value of the awards at grant date. We recognize compensation expense on a straight-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">line basis, after taking into consideration an estimate of forfeitures, over the requisite service period, which is generally the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">vesting period.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For performance-based stock options with vesting based on the achievement of certain strategic milestones, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock-based compensation expense is recognized over the period from the date the performance condition is determined to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">be probable of occurring through the date the applicable condition is expected to be met and is reduced for estimated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">forfeitures, as applicable. If the performance condition is not considered probable of being achieved, no stock-based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">compensation expense is recognized until such time as the performance condition is considered probable of being met, if at </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:571.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">all. If the assessment of probability of the performance condition changes, the impact of the change in estimate would be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recognized in the period of the change. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The grant-date fair value for service-based restricted stock units or restricted stock awards is determined </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">using the fair value of our common stock on the date of grant. The determination of grant-date fair values for our service-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">based and performance-based stock options and employee stock purchases using the Black-Scholes option pricing model is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">affected by our stock price as well as assumptions regarding a number of complex and subjective variables. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Dividend yield is based on historical cash dividend payments and we have paid no cash dividends to date. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The expected volatility range is based on historical volatilities of our stock, since traded options on our common stock do </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">not correspond to option terms and the trading volume of options is limited. The risk‑free interest rate range is based on the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Zero Coupon Treasury Strip Yields for the expected term in effect on the date of grant for an award. The expected </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">term of stock options is derived from actual historical exercise and post‑vesting cancellation data and represents the period </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of time that stock options granted are expected to be outstanding. The expected term of employees’ purchase rights is equal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to the purchase period.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We grant stock options to consultants from time to time in exchange for services performed for us. In </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">general, these stock options vest over the contractual period of the consulting arrangement. The fair value of stock options </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">held by consultants is recorded as operating expenses over the vesting term of the respective equity awards. With the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">adoption of Accounting Standards Update 2018-07, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:267.51pt;position:var(--position);text-decoration:none;white-space:pre">Improvements to Nonemployee Share-Based Payment Accounting</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:530.28pt;position:var(--position);text-decoration:none;white-space:pre">, the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">measurement date of stock options granted to consultants was fixed at the grant date.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Net Loss Per Share</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Basic net income (loss) per share is calculated by dividing net income (loss) by the weighted-average </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">number of shares of common stock outstanding for the periods presented without consideration of potential common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">shares. In connection with previous public offerings, we issued pre-funded warrants to purchase shares of our common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Diluted net income per share would be calculated by adjusting the weighted-average number of shares of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common stock outstanding for the dilutive effect of additional shares of common stock that would have been outstanding if </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">potentially dilutive securities had been issued, as determined using the treasury-stock method. Potential dilutive securities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consist of outstanding stock options and warrants to purchase our common stock. Diluted net loss per share excludes </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">potential dilutive securities for all periods presented as their effect would be anti-dilutive. Accordingly, basic and diluted </span></div>net loss per share is the same for all periods presented in the accompanying consolidated statements of operations. <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Leases</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">At the inception of an arrangement, we determine whether the arrangement is or contains a lease based on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the unique facts and circumstances present. Operating leases are included in operating leases, right-of-use assets and lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">liabilities on our consolidated balance sheets. Right-of-use assets represent our right to use an underlying asset for the lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">term and lease liabilities represent our obligation to make lease payments arising from the lease. Operating lease liabilities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and their corresponding right-of-use assets are recorded based on the present value of remaining lease payments over the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expected lease term. The present value of remaining lease payments within the 12 months following the balance sheet date </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">are classified as current lease liabilities. The present value of lease payments not within the 12 months following the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">balance sheet date are classified as noncurrent lease liabilities. The interest rate implicit in lease contracts is typically not </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:457.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">readily determinable. As such, to calculate the net present value of lease payments, we apply our incremental borrowing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">rate, which is the estimated rate to borrow on a collateralized basis over a similar term an amount equal to the lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">payments in a similar economic environment as of the lease commencement date. We may adjust the right-of-use assets for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">certain adjustments, such as initial direct costs paid or incentives received. In addition, we include any options to extend or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">terminate the lease in the expected lease term when it is reasonably certain that we will exercise any such option. Lease </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:517.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expense is recognized on a straight-line basis over the expected lease term.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:541.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For lease agreements that include lease and non-lease components, such components are generally </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">accounted for separately. We have also elected not to recognize on our consolidated balance sheets leases with terms of one </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">year or less.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Royalty Pharma Agreement Interest Expense </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The liability related to the Royalty Pharma Agreement and the related interest expense are measured based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">on our current estimate of the timing and amount of expected future Royalty Payments expected to be paid over the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">estimated term of the Royalty Pharma Agreement using a discounted cash flow model. The liability is amortized using the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">effective interest rate method, resulting in recognition of non-cash interest expense over the estimated term of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">agreement. Each reporting period, we assess the estimated timing and amount of future expected Royalty Payments over </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the estimated term. If there are changes to the estimate, we recognize the impact to the liability’s amortization schedule and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the related non-cash interest expense prospectively. Additionally, the transaction costs associated with the liability are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">amortized to non-cash interest expense over the estimated term of the Royalty Pharma Agreement.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Income Taxes</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We maintain deferred tax assets and liabilities that reflect the net tax effects of temporary differences </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:109.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">purposes and are subject to tests of recoverability. Our deferred tax assets include net operating loss carryforwards, federal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and state tax credits and capitalized research and development. Deferred tax assets and liabilities are measured using </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recovered or settled. Our net deferred tax asset has been fully offset by a valuation allowance because of our history of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">losses. Any potential accrued interest and penalties related to unrecognized tax benefits would be recorded as income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expense.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Segment Information</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our chief executive officer represents our chief operating decision maker. We view our operations as a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:229.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">single segment, the development of therapeutic products for oncology. As a result, the financial information disclosed </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:241.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">herein materially represents all of the financial information related to our principal operating segment. For additional </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">information, see Note 15 on Segment Reporting.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Recent Accounting Pronouncements</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:301.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">New Accounting Pronouncements – Issued But Not Yet Adopted</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In November 2024, the Financial Standards Accounting Board (FASB) issued Accounting Standards </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Update (ASU)  2024-03, Income Statement - Reporting Comprehensive Income - Expense Disaggregation Disclosures </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(Subtopic 220-40): Disaggregation of Income Statement Expenses. The amendments in ASU 2024-03 address investor </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:355.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">requests for more detailed expense information and require additional disaggregated disclosures in the notes to financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements for certain categories of expenses that are included on the face of the income statement. This guidance is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">effective for fiscal years beginning after December 15, 2026, and interim periods within fiscal years beginning after </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:391.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 15, 2027, with early adoption permitted. We are evaluating the impact of this ASU on our consolidated financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">New Accounting Pronouncements – Issued and Adopted</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">December 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:195.87pt;position:var(--position);text-decoration:none;white-space:pre">, the FASB issued ASU 2023-09, Income Taxes (ASU 2023-09), which requires issuers </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to make additional discloses on an annual basis related to specific categories in the rate reconciliation and provide </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">additional information for reconciling items that meet a quantitative threshold on an annual basis, disclose additional </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">information about income taxes paid as well as other disaggregated disclosures. ASU 2023-09 is effective for the Company </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">as of January 1, 2025 for annual periods. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:223.94pt;position:var(--position);text-decoration:none;white-space:pre">We adopted this standard and applied the disclosure requirements on a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">prospective basis effective for the year ended December 31, 2025. The adoption did not have a material impact on our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consolidated financial position or results of operations. Refer to Note 13, Income Taxes, for our updated income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">disclosure.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In November 2023, the FASB issued ASU 2023-07, Segment Reporting (ASU 2023-07), which requires </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">issuers to make additional disclosures with respect to segment expenses, including required disclosure on an annual and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">interim basis for significant segment expenses and other segment items. The improved disclosure requirements apply to all </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">public entities that are required to report segment information, including those with only </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.2pt;position:var(--position);text-decoration:none;white-space:pre">one</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:428.63pt;position:var(--position);text-decoration:none;white-space:pre"> reportable segment. ASU </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2023-07 also permits the disclosure of more than one measure of a segment’s profit or loss. ASU 2023-07 is effective for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the Company as of January 1, 2024 for annual periods and as of January 1, 2025 for interim periods. We adopted the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">guidance in the annual period ended December 31, 2024. There was no impact on our reportable segments identified and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">additional required disclosures have been included i</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:266.02pt;position:var(--position);text-decoration:none;white-space:pre">n Note 15. We view our operations as a single segment. See Note 15 on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:649.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Segment Reporting.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:673.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Other recent accounting pronouncements issued by the FASB did not or are not believed by management to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have a material impact on our financial statements.</span></div> 1 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">PRODUCT REVENUE </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">To date, our primary source of product revenue has been from the U.S. sales of RYTELO, which we began </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">shipping to our customers in June 2024. To date, product revenue pursuant to NPPs outside of the U.S. have been not </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">material.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The reconciliation of gross product sales to net product sales by each significant category of gross-to-net </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">adjustments was as follows for the years ended</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:246.36pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:248.86pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:327.4pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024:</span></div><div style="position:var(--position);top:169.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:501pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:331.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);width:163.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:163.5pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:36.9pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31, </span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Gross product revenue</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:44.21pt"></span></span><span style="left:50.84pt;position:var(--position)">223,112<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">89,418<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Gross-to-net adjustments:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Chargebacks</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:49.55pt"></span></span><span style="left:52.18pt;position:var(--position)">(25,525)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(8,724)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:63.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Distributor service fees</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(7,512)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(3,048)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:76.5pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government rebates</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:76.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(2,603)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:76.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:59.55pt"></span></span><span style="left:62.18pt;position:var(--position)">(926)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:89.25pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Sales returns and allowances</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:89.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(3,849)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:89.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:59.55pt"></span></span><span style="left:62.18pt;position:var(--position)">(225)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:102pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total gross-to-net adjustments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:102pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.55pt"></span></span><span style="left:52.18pt;position:var(--position)">(39,489)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:102pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.55pt"></span></span><span style="left:52.18pt;position:var(--position)">(12,923)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:114.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Product revenues, net</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:114.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:44.21pt"></span></span><span style="left:50.84pt;position:var(--position)">183,623<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:114.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">76,495<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:314pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:145.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:224.48000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, three customers individually accounted for approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:463.08pt;position:var(--position);text-decoration:none;white-space:pre">45%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:481.41pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:486.41pt;position:var(--position);text-decoration:none;white-space:pre">32%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:504.74pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:524.1700000000001pt;position:var(--position);text-decoration:none;white-space:pre">21%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:542.5pt;position:var(--position);text-decoration:none;white-space:pre"> of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:326pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our gross accounts rec</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:147.57999999999998pt;position:var(--position);text-decoration:none;white-space:pre">eivable associated with our product revenue, as compared to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:391.17pt;position:var(--position);text-decoration:none;white-space:pre">43%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:409.5pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.5pt;position:var(--position);text-decoration:none;white-space:pre">38%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:432.83pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:452.26pt;position:var(--position);text-decoration:none;white-space:pre">17%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:470.59pt;position:var(--position);text-decoration:none;white-space:pre"> as of December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:338pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2024, respectively.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The reconciliation of gross product sales to net product sales by each significant category of gross-to-net </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">adjustments was as follows for the years ended</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:246.36pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:248.86pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:327.4pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024:</span></div><div style="position:var(--position);top:169.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:501pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:331.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);width:163.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:163.5pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:36.9pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31, </span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Gross product revenue</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:44.21pt"></span></span><span style="left:50.84pt;position:var(--position)">223,112<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">89,418<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Gross-to-net adjustments:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Chargebacks</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:49.55pt"></span></span><span style="left:52.18pt;position:var(--position)">(25,525)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(8,724)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:63.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Distributor service fees</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(7,512)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(3,048)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:76.5pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government rebates</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:76.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(2,603)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:76.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:59.55pt"></span></span><span style="left:62.18pt;position:var(--position)">(926)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:89.25pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Sales returns and allowances</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:89.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:53.55pt"></span></span><span style="left:56.18pt;position:var(--position)">(3,849)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:89.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:59.55pt"></span></span><span style="left:62.18pt;position:var(--position)">(225)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:102pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total gross-to-net adjustments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:102pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.55pt"></span></span><span style="left:52.18pt;position:var(--position)">(39,489)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:102pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.55pt"></span></span><span style="left:52.18pt;position:var(--position)">(12,923)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:114.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Product revenues, net</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:334.5pt;position:var(--position);top:114.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:44.21pt"></span></span><span style="left:50.84pt;position:var(--position)">183,623<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:417.75pt;position:var(--position);top:114.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">76,495<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 223112000 89418000 -25525000 -8724000 -7512000 -3048000 -2603000 -926000 -3849000 -225000 -39489000 -12923000 183623000 76495000 0.45 0.32 0.21 0.43 0.38 0.17 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">INVENTORY</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:392pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">All of our inventories are related to the manufacturing of RYTELO. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:395.62pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:404pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">inventory as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:120.95pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:199.49pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024: </span></div><div style="position:var(--position);top:422pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:498pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:328.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="4" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);width:166.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:166.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:59.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Raw materials</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:58.84pt;position:var(--position)">8,927<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:58.84pt;position:var(--position)">4,904<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Work-in-process</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:38.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:54.84pt;position:var(--position)">91,969<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:38.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">30,093<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Finished goods</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:54.84pt;position:var(--position)">15,740<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:58.84pt;position:var(--position)">3,717<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:63.75pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total inventory</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:44.21pt"></span></span><span style="left:50.84pt;position:var(--position)">116,636<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">38,714<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:527.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:124pt;position:var(--position);text-decoration:none;white-space:pre">Prior to the FDA’s approval of RYTELO, all costs for the manufacture of product to support clinical </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:539.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">development and commercial launch, including pre-launch inventory, were expensed as incurred. Pre-launch inventory </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:551.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">manufactured prior to the FDA approval of RYTELO will be used in commercial production until it is depleted.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:395.62pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents our </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:404pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">inventory as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:120.95pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:199.49pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024: </span></div><div style="position:var(--position);top:422pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:498pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:328.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="4" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);width:166.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:166.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:59.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Raw materials</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:58.84pt;position:var(--position)">8,927<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:58.84pt;position:var(--position)">4,904<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Work-in-process</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:38.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:54.84pt;position:var(--position)">91,969<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:38.25pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">30,093<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Finished goods</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:54.84pt;position:var(--position)">15,740<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:51pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:52.21pt"></span></span><span style="left:58.84pt;position:var(--position)">3,717<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:63.75pt;width:328.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:328.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total inventory</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:44.21pt"></span></span><span style="left:50.84pt;position:var(--position)">116,636<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:63.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:48.21pt"></span></span><span style="left:54.84pt;position:var(--position)">38,714<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 8927000 4904000 91969000 30093000 15740000 3717000 116636000 38714000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">FINANCIAL INSTRUMENTS</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents, restricted cash and marketable securities by security type at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.39pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:512.9300000000001pt;position:var(--position);text-decoration:none;white-space:pre"> were as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">follows:</span></div><div style="position:var(--position);top:115.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:222pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.05pt;position:var(--position);text-decoration:none;white-space:pre">Amortized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:24pt;width:222pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.48pt;position:var(--position);text-decoration:none;white-space:pre">Cost</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gains</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:21.14pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.93pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:36pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Included in cash and cash equivalents:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">48,950<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:55.42pt;position:var(--position)">1<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">48,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:66pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,979<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,979<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">53,929<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:55.42pt;position:var(--position)">1<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">53,930<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:111.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Restricted cash:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:126.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market fund</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,606<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,606<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:141.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,880<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,880<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:171.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Marketable securities:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:186.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,910<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">41<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:201.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in one to two years)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:216.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Municipal securities (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">10,032<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">9<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">10,041<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:231.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government-sponsored enterprise securities (due in </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:258.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">79,354<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">49<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">79,403<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:273.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">167,805<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">175<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(16)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">167,964<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:288.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two years)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">41,316<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">11<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(38)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">41,289<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">321,417<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:37.79pt"></span></span><span style="left:45.42pt;position:var(--position)">285<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:39.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(54)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">321,648<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents, restricted cash and marketable securities by security type at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.39pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:512.9300000000001pt;position:var(--position);text-decoration:none;white-space:pre"> were as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:222pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.05pt;position:var(--position);text-decoration:none;white-space:pre">Amortized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:24pt;width:222pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.48pt;position:var(--position);text-decoration:none;white-space:pre">Cost</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gains</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:21.14pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.93pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:36pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Included in cash and cash equivalents:</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">45,215<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">45,215<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:66pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,978<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:49.46pt"></span></span><span style="left:52.09pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,977<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">50,193<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:52.09pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">50,192<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:111.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Restricted cash:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:126.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market fund</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,587<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,587<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:141.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,860<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,860<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:171.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Marketable securities:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:186.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">7,937<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">22<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">7,959<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:201.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in one to two years)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,620<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">1<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(11)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,610<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:216.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government-sponsored enterprise securities (due in </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">8,741<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">7<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">8,748<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:243.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">180,131<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">150<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(56)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">180,225<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:258.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">130,361<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">284<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(27)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">130,618<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:273.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two years)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">72,000<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(97)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">71,909<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">421,790<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:37.79pt"></span></span><span style="left:45.42pt;position:var(--position)">470<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:34.46pt"></span></span><span style="left:42.09pt;position:var(--position)">(191)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">422,069<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents and marketable securities with unrealized losses that have been in a continuous unrealized </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">loss position for less than 12 months and 12 months or longer at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:316.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:395.48pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.91pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.91pt;position:var(--position);text-decoration:none;white-space:pre"> were as follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:172.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);width:103.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:103.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.99pt;position:var(--position);text-decoration:none;white-space:pre">Less Than 12 Months</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);width:103.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:103.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.44pt;position:var(--position);text-decoration:none;white-space:pre">12 Months or Longer</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);width:103.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:103.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:42.64pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:12.75pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.13pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:12.75pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.13pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:12.75pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.13pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:7.81pt;position:var(--position);text-decoration:none;white-space:pre">Estimated</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.48pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.48pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.48pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:172.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.81pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.02pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.81pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.02pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.81pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.02pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2025:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:81pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:108pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:135pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">17,987<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(16)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">17,987<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(16)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:162pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">years)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">31,265<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(38)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">31,265<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(38)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">49,252<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(54)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">49,252<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(54)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:204pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2024:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:218.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">18,593<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(10)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">18,593<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(10)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:245.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">66,076<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(56)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">66,076<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(56)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:272.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">31,549<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(26)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:21.04pt"></span></span><span style="left:23.669999999999998pt;position:var(--position)">1,993<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.21pt"></span></span><span style="left:37.84pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">33,542<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(27)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:299.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">years)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">53,506<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(98)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">53,506<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(98)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:6.04pt"></span></span><span style="left:13.669999999999998pt;position:var(--position)">169,724<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.21pt"></span></span><span style="left:27.84pt;position:var(--position)">(190)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:23.669999999999998pt;position:var(--position)">1,993<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:37.84pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:6.04pt"></span></span><span style="left:13.669999999999998pt;position:var(--position)">171,717<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.21pt"></span></span><span style="left:27.84pt;position:var(--position)">(191)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:461.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The gross unrealized losses related to U.S. Treasury securities, municipal securities, government-sponsored </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:473.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">enterprise securities, commercial paper and corporate notes as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:319.8pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:398.34pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:417.77pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:437.77pt;position:var(--position);text-decoration:none;white-space:pre"> were due to changes in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:485.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">interest rates and not credit risk. If an available-for-sale security’s fair value is less than its amortized cost basis, we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:497.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">evaluate whether the decline is the result of a credit loss, in which case an impairment is recorded through an allowance for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:509.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">credit losses. We have not recorded any allowances for credit losses on our available-for-sale securities for the years ended </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:521.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:137.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:156.47pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:176.47pt;position:var(--position);text-decoration:none;white-space:pre"> as we have not identified any unrealized losses for these securities attributable to credit </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:533.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">factors. Our exposure to unrealized losses may increase in the future due to the economic pressures or uncertainties </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:545.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">associated with local or global economic recessions as a result of ongoing geopolitical events, such as the current military </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:557.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">conflict between Ukraine and Russia, as well as recent and potential future disruptions in access to bank deposits or lending </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:569.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">commitments due to bank failure. We do not intend to sell the investments and it is not more likely that not that we will be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:581.75pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">required to sell the investments before recovery of their amortized cost basis, which may be maturity.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents, restricted cash and marketable securities by security type at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.39pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:512.9300000000001pt;position:var(--position);text-decoration:none;white-space:pre"> were as </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">follows:</span></div><div style="position:var(--position);top:115.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:222pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.05pt;position:var(--position);text-decoration:none;white-space:pre">Amortized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:24pt;width:222pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.48pt;position:var(--position);text-decoration:none;white-space:pre">Cost</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gains</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:21.14pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.93pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:36pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Included in cash and cash equivalents:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">48,950<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:55.42pt;position:var(--position)">1<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">48,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:66pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,979<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,979<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">53,929<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:55.42pt;position:var(--position)">1<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">53,930<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:111.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Restricted cash:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:126.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market fund</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,606<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,606<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:141.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,880<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,880<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:171.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Marketable securities:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:186.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,910<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">41<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:201.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in one to two years)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:216.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Municipal securities (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">10,032<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">9<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">10,041<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:231.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government-sponsored enterprise securities (due in </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:231.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:258.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">79,354<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">49<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">79,403<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:273.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">167,805<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">175<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(16)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">167,964<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:288.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two years)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">41,316<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">11<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(38)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">41,289<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">321,417<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:37.79pt"></span></span><span style="left:45.42pt;position:var(--position)">285<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:39.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(54)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:303.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">321,648<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents, restricted cash and marketable securities by security type at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.39pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:512.9300000000001pt;position:var(--position);text-decoration:none;white-space:pre"> were as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:222pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:64.5pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.05pt;position:var(--position);text-decoration:none;white-space:pre">Amortized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:12pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.6pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:24pt;width:222pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.48pt;position:var(--position);text-decoration:none;white-space:pre">Cost</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:22.25pt;position:var(--position);text-decoration:none;white-space:pre">Gains</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:21.14pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:24pt;width:64.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:13.93pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:36pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Included in cash and cash equivalents:</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">45,215<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:51pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">45,215<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:66pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,978<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:49.46pt"></span></span><span style="left:52.09pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:66pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">4,977<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">50,193<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:52.09pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:81pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:32.92pt;position:var(--position)">50,192<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:111.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Restricted cash:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:126.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market fund</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,587<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:126.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,587<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:141.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:141.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,860<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:156.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">1,860<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:171.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Marketable securities:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:186.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">7,937<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">22<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:186.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:37.92pt;position:var(--position)">7,959<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:201.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in one to two years)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,620<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">1<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(11)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:201.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">22,610<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:216.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government-sponsored enterprise securities (due in </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">8,741<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">7<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.79pt"></span></span><span style="left:50.42pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:216.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.29pt"></span></span><span style="left:37.92pt;position:var(--position)">8,748<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:243.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">180,131<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">150<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(56)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:243.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">180,225<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:258.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">130,361<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.79pt"></span></span><span style="left:45.42pt;position:var(--position)">284<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(27)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:258.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">130,618<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:273.75pt;width:222pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:222pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two years)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">72,000<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.79pt"></span></span><span style="left:55.42pt;position:var(--position)">6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.46pt"></span></span><span style="left:47.09pt;position:var(--position)">(97)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:273.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.29pt"></span></span><span style="left:32.92pt;position:var(--position)">71,909<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:225pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">421,790<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:292.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:37.79pt"></span></span><span style="left:45.42pt;position:var(--position)">470<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:360pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:34.46pt"></span></span><span style="left:42.09pt;position:var(--position)">(191)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:427.5pt;position:var(--position);top:288.75pt;width:64.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:64.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.29pt"></span></span><span style="left:27.919999999999998pt;position:var(--position)">422,069<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div></div> 48950000 1000 0 48951000 4979000 0 0 4979000 53929000 1000 0 53930000 1606000 0 0 1606000 274000 0 0 274000 1880000 0 0 1880000 22910000 41000 0 22951000 0 0 0 0 10032000 9000 0 10041000 0 0 0 0 79354000 49000 0 79403000 167805000 175000 16000 167964000 41316000 11000 38000 41289000 321417000 285000 54000 321648000 45215000 0 0 45215000 4978000 0 1000 4977000 50193000 0 1000 50192000 1587000 0 0 1587000 273000 0 0 273000 1860000 0 0 1860000 7937000 22000 0 7959000 22620000 1000 11000 22610000 8741000 7000 0 8748000 180131000 150000 56000 180225000 130361000 284000 27000 130618000 72000000 6000 97000 71909000 421790000 470000 191000 422069000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Cash equivalents and marketable securities with unrealized losses that have been in a continuous unrealized </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">loss position for less than 12 months and 12 months or longer at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:316.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:395.48pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.91pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.91pt;position:var(--position);text-decoration:none;white-space:pre"> were as follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:172.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:50.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);width:103.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:103.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.99pt;position:var(--position);text-decoration:none;white-space:pre">Less Than 12 Months</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);width:103.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:103.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.44pt;position:var(--position);text-decoration:none;white-space:pre">12 Months or Longer</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);width:103.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:103.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:42.64pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:12.75pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.13pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:12.75pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.13pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:12.75pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:15.13pt;position:var(--position);text-decoration:none;white-space:pre">Gross</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:7.81pt;position:var(--position);text-decoration:none;white-space:pre">Estimated</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.48pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.48pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:25.5pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.48pt;position:var(--position);text-decoration:none;white-space:pre">Unrealized</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:172.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.81pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.02pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.81pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.02pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.81pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:38.25pt;width:50.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.02pt;position:var(--position);text-decoration:none;white-space:pre">Losses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2025:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:81pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:81pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:108pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:108pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:135pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">17,987<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(16)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">17,987<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:135pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(16)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:162pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">years)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">31,265<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(38)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">31,265<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:162pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(38)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">49,252<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(54)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">49,252<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:189pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(54)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:204pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2024:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:218.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities (due in less </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">than one year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">18,593<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(10)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:11.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">18,593<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:218.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(10)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:245.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper (due in less than </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">one year)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">66,076<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(56)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">66,076<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:245.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(56)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:272.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in less than one </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">year)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">31,549<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(26)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:21.04pt"></span></span><span style="left:23.669999999999998pt;position:var(--position)">1,993<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.21pt"></span></span><span style="left:37.84pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">33,542<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:272.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(27)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:299.25pt;width:172.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes (due in one to two </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:172.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">years)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">53,506<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(98)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.54pt"></span></span><span style="left:36.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:18.669999999999998pt;position:var(--position)">53,506<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:299.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:32.84pt;position:var(--position)">(98)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:175.5pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:6.04pt"></span></span><span style="left:13.669999999999998pt;position:var(--position)">169,724<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:228.75pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.21pt"></span></span><span style="left:27.84pt;position:var(--position)">(190)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:282pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:16.04pt"></span></span><span style="left:23.669999999999998pt;position:var(--position)">1,993<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:335.25pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.21pt"></span></span><span style="left:37.84pt;position:var(--position)">(1)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:388.5pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:6.04pt"></span></span><span style="left:13.669999999999998pt;position:var(--position)">171,717<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:441.75pt;position:var(--position);top:326.25pt;width:50.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.75pt;width:50.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.21pt"></span></span><span style="left:27.84pt;position:var(--position)">(191)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 0 0 0 0 0 0 0 0 0 0 0 0 17987000 16000 0 0 17987000 16000 31265000 38000 0 0 31265000 38000 49252000 54000 0 0 49252000 54000 18593000 10000 0 0 18593000 10000 66076000 56000 0 0 66076000 56000 31549000 26000 1993000 1000 33542000 27000 53506000 98000 0 0 53506000 98000 169724000 190000 1993000 1000 171717000 191000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">FAIR VALUE MEASUREMENTS</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents information about our financial instruments that are measured at fair value on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">a recurring basis as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:148.68pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:227.22pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:246.65pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:266.65pt;position:var(--position);text-decoration:none;white-space:pre"> and indicates the fair value category assigned.</span></div><div style="position:var(--position);top:151.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:240pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="7" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);width:249pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:249pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:37.69pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value Measurements at Reporting Date Using</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:240pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.67pt;position:var(--position);text-decoration:none;white-space:pre">Level 1</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.67pt;position:var(--position);text-decoration:none;white-space:pre">Level 2</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.67pt;position:var(--position);text-decoration:none;white-space:pre">Level 3</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:20.89pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2025:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:39.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Assets:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:54.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:94.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(1)(2)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">50,557<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">50,557<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:69.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:95.94pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(2)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:84.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Municipal securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:92.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">10,041<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">10,041<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:99.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:107.63pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">22,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">22,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:114.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:85.67999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">84,382<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">84,382<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:129.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:75.17pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">209,253<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">209,253<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:144.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:17.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">50,831<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">326,627<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">377,458<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:159.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Liabilities:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:174.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Sale of future royalties</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:102.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(5)(6)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:189.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:17.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:204.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2024:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:219pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Assets:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:234pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:94.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(1)(2)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">46,802<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">46,802<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:249pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:95.94pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(2)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:264pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:107.63pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">30,570<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">30,570<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:279pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government-sponsored enterprise securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:187.54pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.79pt"></span></span><span style="left:33.42pt;position:var(--position)">8,748<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.79pt"></span></span><span style="left:33.42pt;position:var(--position)">8,748<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:294pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:85.67999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">185,201<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">185,201<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:309pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:75.17pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">202,527<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">202,527<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:324pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">47,075<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">427,046<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">474,121<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:339pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Liabilities:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:354pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Sale of future royalties</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:102.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(5)(6)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:369pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:17.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="position:var(--position);top:540.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:128.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:128.25pt"></td></tr><tr style="height:4.5pt"><td style="border-bottom:1pt solid #000000;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:556pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(1)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in cash and cash equivalents on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:574pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(2)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in restricted cash on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:592pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(3)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in current portion of marketable securities on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:610pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(4)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in noncurrent portion of marketable securities on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:628pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(5)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in current portion of liabilities related to sale of future royalties on our consolidated balance </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:640pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:658pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(6)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in noncurrent portion of liabilities related to sale of future royalties on our consolidated balance </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:670pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:688pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds and certificates of deposit are categorized as Level 1 within the fair value hierarchy as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:700pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">their fair values are based on quoted prices available in active markets. Commercial paper, U.S. Treasury securities, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:712pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">municipal securities, government-sponsored enterprise securities and corporate notes are categorized as Level 2 within the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:724pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">fair value hierarchy as their fair values are estimated by using pricing models, quoted prices of securities with similar </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:736pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">characteristics or discounted cash flows.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">There were </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:169.2pt;position:var(--position);text-decoration:none;white-space:pre">no</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:179.2pt;position:var(--position);text-decoration:none;white-space:pre"> transfers between Level 1, Level 2, and Level 3 during the periods presented. There have </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">been no impairments of our assets measured and carried at fair value as of December 31, 2025 and 2024. In addition, there </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">have been no changes to our valuation techniques as of December 31, 2025 and 2024.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The embedded derivatives are classified within Level 3 of the fair value hierarchy. See Note 10 on Debt.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We determined the fair value of the liability related to the sale of future royalties based on our current </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">estimates of future royalties expected to be paid to Royalty Pharma over the life of the arrangement, which are considered </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Level 3. See Note 10 on Debt.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents information about our financial instruments that are measured at fair value on </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">a recurring basis as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:148.68pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:227.22pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:246.65pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:266.65pt;position:var(--position);text-decoration:none;white-space:pre"> and indicates the fair value category assigned.</span></div><div style="position:var(--position);top:151.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:240pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:60pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="7" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);width:249pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:249pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:37.69pt;position:var(--position);text-decoration:none;white-space:pre">Fair Value Measurements at Reporting Date Using</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:240pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.67pt;position:var(--position);text-decoration:none;white-space:pre">Level 1</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.67pt;position:var(--position);text-decoration:none;white-space:pre">Level 2</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.67pt;position:var(--position);text-decoration:none;white-space:pre">Level 3</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:12.75pt;width:60pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:20.89pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2025:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:39.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Assets:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:54.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:94.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(1)(2)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">50,557<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:54.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">50,557<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:69.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:95.94pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(2)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:69.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">274<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:84.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Municipal securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:92.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">10,041<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:84.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">10,041<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:99.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:107.63pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">22,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:99.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">22,951<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:114.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:85.67999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">84,382<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:114.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">84,382<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:129.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:75.17pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">209,253<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:129.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">209,253<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:144.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:17.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">50,831<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">326,627<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:144.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">377,458<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:159.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Liabilities:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:174.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Sale of future royalties</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:102.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(5)(6)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:174.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:189.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:17.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:189.75pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:204.75pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, 2024:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:219pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Assets:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:234pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Money market funds</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:94.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(1)(2)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">46,802<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:234pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">46,802<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:249pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Certificate of deposit</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:95.94pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(2)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:249pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:40.92pt;position:var(--position)">273<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:264pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">U.S. Treasury securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:107.63pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">30,570<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:264pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">30,570<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:279pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Government-sponsored enterprise securities</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:187.54pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.79pt"></span></span><span style="left:33.42pt;position:var(--position)">8,748<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:279pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.79pt"></span></span><span style="left:33.42pt;position:var(--position)">8,748<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:294pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial paper</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:85.67999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">185,201<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:294pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">185,201<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:309pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Corporate notes</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:75.17pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(3)(4)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">202,527<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:309pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">202,527<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:324pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:28.419999999999998pt;position:var(--position)">47,075<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">427,046<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:324pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">474,121<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:339pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Liabilities:</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:354pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Sale of future royalties</span><span style="font-family:'Times New Roman', serif;font-size:6.5pt;font-style:normal;font-weight:normal;left:102.89999999999999pt;position:var(--position);text-decoration:none;top:-2.4254999999999995pt;vertical-align:super;white-space:pre">(5)(6)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:354pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:20.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:369pt;width:240pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:240pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:17.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:243pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:306pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.29pt"></span></span><span style="left:45.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:369pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:432pt;position:var(--position);top:369pt;width:60pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:60pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.79pt"></span></span><span style="left:23.419999999999998pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="position:var(--position);top:540.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:128.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:128.25pt"></td></tr><tr style="height:4.5pt"><td style="border-bottom:1pt solid #000000;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:556pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(1)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in cash and cash equivalents on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:574pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(2)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in restricted cash on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:592pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(3)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in current portion of marketable securities on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:610pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(4)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in noncurrent portion of marketable securities on our consolidated balance sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:628pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(5)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in current portion of liabilities related to sale of future royalties on our consolidated balance </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:640pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">sheets.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:658pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(6)</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Included in noncurrent portion of liabilities related to sale of future royalties on our consolidated balance </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:670pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">sheets.</span></div> 50557000 0 0 50557000 274000 0 0 274000 0 10041000 0 10041000 0 22951000 0 22951000 0 84382000 0 84382000 0 209253000 0 209253000 50831000 326627000 0 377458000 0 0 129582000 129582000 0 0 129582000 129582000 46802000 0 0 46802000 273000 0 0 273000 0 30570000 0 30570000 0 8748000 0 8748000 0 185201000 0 185201000 0 202527000 0 202527000 47075000 427046000 0 474121000 0 0 124793000 124793000 0 0 124793000 124793000 0 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">PROPERTY AND EQUIPMENT</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Property and equipment is recorded at historical cost, net of accumulated depreciation and is comprised of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the following:</span></div><div style="position:var(--position);top:271.5pt;width:612pt"><div style="font-size:0pt;left:129.37pt;position:var(--position);width:353.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:216.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);width:133.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:133.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:43.44pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:216.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Furniture and computer equipment</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">2,959<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">2,878<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Leasehold improvements</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">129<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">129<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,088<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,007<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less accumulated depreciation and amortization</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:32.71pt"></span></span><span style="left:35.34pt;position:var(--position)">(2,204)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:32.71pt"></span></span><span style="left:35.34pt;position:var(--position)">(1,697)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.54pt"></span></span><span style="left:46.17pt;position:var(--position)">884<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,310<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Property and equipment is recorded at historical cost, net of accumulated depreciation and is comprised of </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the following:</span></div><div style="position:var(--position);top:271.5pt;width:612pt"><div style="font-size:0pt;left:129.37pt;position:var(--position);width:353.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:216.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);width:133.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:133.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:43.44pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:216.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Furniture and computer equipment</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">2,959<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">2,878<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Leasehold improvements</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">129<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">129<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,088<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,007<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less accumulated depreciation and amortization</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:32.71pt"></span></span><span style="left:35.34pt;position:var(--position)">(2,204)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:32.71pt"></span></span><span style="left:35.34pt;position:var(--position)">(1,697)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:38.54pt"></span></span><span style="left:46.17pt;position:var(--position)">884<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,310<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 2959000 2878000 129000 129000 3088000 3007000 2204000 1697000 884000 1310000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">OTHER CONSOLIDATED FINANCIAL STATEMENT DETAILS</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:431pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Accrued liabilities consisted of the following:</span></div><div style="position:var(--position);top:455pt;width:612pt"><div style="font-size:0pt;left:127.87pt;position:var(--position);width:356.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:216.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);width:133.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:133.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:43.44pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:216.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">CRO and clinical trial costs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,677<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">18,968<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Manufacturing activities</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">38,657<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">11,839<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Professional legal and accounting fees</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">881<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">475<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Interest payable</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,110<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">2,186<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued revenue adjustments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,486<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,038<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:100.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:100.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,529<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:100.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,043<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:115.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">51,340<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:115.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">35,549<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Accrued compensation and benefits consisted of the following: </span></div><div style="position:var(--position);top:91.5pt;width:612pt"><div style="font-size:0pt;left:121.5pt;position:var(--position);width:376.5pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:230.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:71.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);width:143.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:143.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:48.31pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:230.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:12.75pt;width:69pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:12.75pt;width:71.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:27.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued bonuses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:25.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">10,335<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:25.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:32.04pt"></span></span><span style="left:39.67pt;position:var(--position)">18,056<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued vacation</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:40.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:39.79pt"></span></span><span style="left:42.42pt;position:var(--position)">2,581<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:40.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.04pt"></span></span><span style="left:44.67pt;position:var(--position)">2,928<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued 401K match</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:55.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.29pt"></span></span><span style="left:54.92pt;position:var(--position)">17<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:55.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.04pt"></span></span><span style="left:44.67pt;position:var(--position)">1,685<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued restructuring charges</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:70.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:34.79pt"></span></span><span style="left:37.42pt;position:var(--position)">17,032<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:70.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:54.54pt"></span></span><span style="left:57.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued other</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:85.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.29pt"></span></span><span style="left:49.92pt;position:var(--position)">532<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:85.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:49.54pt"></span></span><span style="left:52.17pt;position:var(--position)">139<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:100.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">30,497<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:100.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:32.04pt"></span></span><span style="left:39.67pt;position:var(--position)">22,808<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Accrued liabilities consisted of the following:</span><div style="position:var(--position);top:455pt;width:612pt"><div style="font-size:0pt;left:127.87pt;position:var(--position);width:356.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:216.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);width:133.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:133.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:43.44pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:216.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">CRO and clinical trial costs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,677<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">18,968<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Manufacturing activities</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">38,657<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">11,839<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Professional legal and accounting fees</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">881<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:43.54pt"></span></span><span style="left:46.17pt;position:var(--position)">475<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Interest payable</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,110<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:70.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">2,186<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued revenue adjustments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">3,486<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:85.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,038<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:100.5pt;width:216.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:216.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:100.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,529<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:100.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:36.04pt"></span></span><span style="left:38.67pt;position:var(--position)">1,043<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219.75pt;position:var(--position);top:115.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">51,340<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:288pt;position:var(--position);top:115.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">35,549<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 3677000 18968000 38657000 11839000 881000 475000 3110000 2186000 3486000 1038000 1529000 1043000 51340000 35549000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Accrued compensation and benefits consisted of the following: </span><div style="position:var(--position);top:91.5pt;width:612pt"><div style="font-size:0pt;left:121.5pt;position:var(--position);width:376.5pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:230.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:71.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);width:143.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:143.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:48.31pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:230.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:12.75pt;width:69pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:12.75pt;width:71.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:27.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued bonuses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:25.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">10,335<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:25.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:32.04pt"></span></span><span style="left:39.67pt;position:var(--position)">18,056<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued vacation</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:40.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:39.79pt"></span></span><span style="left:42.42pt;position:var(--position)">2,581<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:40.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.04pt"></span></span><span style="left:44.67pt;position:var(--position)">2,928<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued 401K match</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:55.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.29pt"></span></span><span style="left:54.92pt;position:var(--position)">17<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:55.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:42.04pt"></span></span><span style="left:44.67pt;position:var(--position)">1,685<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued restructuring charges</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:70.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:34.79pt"></span></span><span style="left:37.42pt;position:var(--position)">17,032<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:70.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:54.54pt"></span></span><span style="left:57.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:230.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:230.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued other</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:85.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.29pt"></span></span><span style="left:49.92pt;position:var(--position)">532<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:85.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:49.54pt"></span></span><span style="left:52.17pt;position:var(--position)">139<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:233.25pt;position:var(--position);top:100.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">30,497<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:305.25pt;position:var(--position);top:100.5pt;width:71.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:71.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:32.04pt"></span></span><span style="left:39.67pt;position:var(--position)">22,808<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 10335000 18056000 2581000 2928000 17000 1685000 17032000 0 532000 139000 30497000 22808000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">COMMITMENTS AND CONTINGENCIES</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:260pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Legal Proceedings</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:278pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On March 13 and March 14, 2025, we and certain of our current and former officers were named as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:290pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">defendants in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:114.55pt;position:var(--position);text-decoration:none;white-space:pre">two</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:129.54000000000002pt;position:var(--position);text-decoration:none;white-space:pre"> putative securities class action lawsuits, each filed in the United States District Court for the Northern </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:302pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">District of California, captioned </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:188.6pt;position:var(--position);text-decoration:none;white-space:pre">Dabestani v. Geron Corporation, et al.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:344.6pt;position:var(--position);text-decoration:none;white-space:pre">, No. 3:25-cv-02507 and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:445.11pt;position:var(--position);text-decoration:none;white-space:pre">Potvin v. Geron </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:314pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Corporation, et al.,</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:135.95pt;position:var(--position);text-decoration:none;white-space:pre"> No. 3:25-cv-02563, respectively. Both lawsuits allege violations of Sections 10(b) and 20(a) of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:326pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Securities Exchange Act of 1934, as amended, or the Exchange Act, and Rule 10b-5 promulgated thereunder in connection </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:338pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with allegedly false and misleading statements concerning the commercial potential of RYTELO. The plaintiffs allege, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:350pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">among other things, that we overstated RYTELO's commercial potential by making materially false and misleading </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:362pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements and/or concealing material adverse facts concerning RYTELO's commercial potential, including the lack of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:374pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">awareness among healthcare providers for RYTELO, the burden of monitoring requirements in administering the drug, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:386pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the impacts of seasonality and existing competition on RYTELO's sales, and that our stock price dropped when we </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:398pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">disclosed in our earnings call on February 26, 2025, that we had observed flat revenue trends over the prior few months. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:410pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The plaintiffs seek damages and interest, and an award of reasonable costs, including attorneys' and experts' fees. On May </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:422pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">29, 2025, the Court consolidated the </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:206.15pt;position:var(--position);text-decoration:none;white-space:pre">Dabestani </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:249.73pt;position:var(--position);text-decoration:none;white-space:pre">and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:266.65999999999997pt;position:var(--position);text-decoration:none;white-space:pre">Potvin</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:292.73pt;position:var(--position);text-decoration:none;white-space:pre"> cases into one consolidated action captioned </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:474.99pt;position:var(--position);text-decoration:none;white-space:pre">In re Geron </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:434pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Corporation Securities Litigation</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:192.27pt;position:var(--position);text-decoration:none;white-space:pre">, or the Securities Class Action, and appointed lead plaintiffs and counsel for lead </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:446pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">plaintiffs. On August 8, 2025, lead plaintiffs filed a consolidated amended complaint. On October 7, 2025, we filed our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:458pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">motion to dismiss the consolidated amended complaint. A hearing on the motion to dismiss is scheduled for March 19, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:470pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2026. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:494pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On April 15, 2025 and April 16, 2025, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:277.83000000000004pt;position:var(--position);text-decoration:none;white-space:pre">three</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:297.78999999999996pt;position:var(--position);text-decoration:none;white-space:pre"> purported stockholders filed derivative complaints, each in the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:506pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">United States District Court for the Northern District of California, captioned </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:369.79pt;position:var(--position);text-decoration:none;white-space:pre">Bishop v. Scarlett, et al</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:463.01pt;position:var(--position);text-decoration:none;white-space:pre">., No. 3:25-cv-03356, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:518pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Lerner v. Scarlett, et al.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:153.66pt;position:var(--position);text-decoration:none;white-space:pre">, No. 3:25-cv-03401, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:256.66999999999996pt;position:var(--position);text-decoration:none;white-space:pre">Willis v. Scarlett, et al</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:345.43pt;position:var(--position);text-decoration:none;white-space:pre">., No: 3:25-cv-03396, respectively. The </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:505.56pt;position:var(--position);text-decoration:none;white-space:pre">three</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:525.52pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:530pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">derivative lawsuits name certain of our current and former directors and officers and allege that they breached their </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:542pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">fiduciary duties and violated federal securities laws by issuing allegedly false and misleading statements concerning the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:554pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">commercial potential of RYTELO. The allegations in each of the </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:321.18pt;position:var(--position);text-decoration:none;white-space:pre">three</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:341.14pt;position:var(--position);text-decoration:none;white-space:pre"> derivative complaints are substantially similar to the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:566pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">two</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:73.49pt;position:var(--position);text-decoration:none;white-space:pre"> aforementioned securities class action lawsuits, which these lawsuits are premised on. Each of the </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:469.92pt;position:var(--position);text-decoration:none;white-space:pre">three</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:489.88pt;position:var(--position);text-decoration:none;white-space:pre"> plaintiffs seek </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:578pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">damages and interest, and an award of reasonable costs, including attorneys' and experts' fees. The plaintiffs in Bishop v. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:590pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Scarlett, et al. and Willis v. Scarlett, et al. also seek punitive damages. On May 16, 2025, the Court consolidated the </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:524.3299999999999pt;position:var(--position);text-decoration:none;white-space:pre">three</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:544.29pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:602pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">derivative complaints into </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:165.3pt;position:var(--position);text-decoration:none;white-space:pre">one</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:179.73000000000002pt;position:var(--position);text-decoration:none;white-space:pre"> consolidated action captioned </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:303.45pt;position:var(--position);text-decoration:none;white-space:pre">In re Geron Corporation Derivative Litigation</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:489.67pt;position:var(--position);text-decoration:none;white-space:pre">, or the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:614pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Consolidated Derivative Action.  On June 17, 2025, the Court stayed the Consolidated Derivative Action pending a final </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:626pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ruling on the anticipated motion to dismiss in the Securities Class Action.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:650pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On August 29, 2025, a purported stockholder made a demand on our board of directors to commence a civil </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:662pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">action against certain of our current and former directors for breaching their fiduciary duties and violating the securities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:674pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">laws by issuing allegedly false and misleading statements concerning the commercial potential of RYTELO.  On </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:686pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">September 19, 2025, the board of directors responded that it would defer a final decision on the demand given the other </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:698pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">pending derivative lawsuits and the Securities Class Action.  On October 7, 2025, the purported stockholder filed a suit in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:710pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the United States District Court for the Northern District of California, captioned Jae Hyung v. Bir, et al., No. 3:25-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:722pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">cv-08575.  The derivative lawsuit names certain of our current and former directors and officers. The allegations in the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:734pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">derivative lawsuit are substantially similar to the Securities Class Action and the aforementioned derivative lawsuits.  The </span></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">plaintiffs seek damages and an award of reasonable costs, including attorneys’ and experts’ fees. On January 23 and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">February 19, 2026, respectively, two additional purported stockholders each made a similar demand on our board of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">directors.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">It is possible that additional lawsuits will be filed or allegations made by stockholders with respect to these </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">same or other matters and also naming us and/or our officers and directors as defendants. We intend to vigorously defend </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">against the claims brought by the plaintiffs in these matters.    </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Such lawsuits are subject to inherent uncertainties, and the actual defense and disposition costs will depend </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">upon many unknown factors. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:177.6pt;position:var(--position);text-decoration:none;white-space:pre">The outcome of the pending lawsuits and any other related lawsuits is necessarily uncertain.  </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">We could be forced to expend significant resources </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:266.03pt;position:var(--position);text-decoration:none;white-space:pre">and may incur substantial legal fees and costs </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:450.8pt;position:var(--position);text-decoration:none;white-space:pre">in defending against the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">pending lawsuits and any other related lawsuits, and we may not prevail. Monitoring, initiating and defending against legal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">actions is time-consuming for our management, is likely to be expensive, and may detract from our ability to fully focus </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our internal resources on our business activities.  Additionally, we may not be successful in having any such lawsuits </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">dismissed or settled within the limits of our insurance coverage. Given the early stage of these lawsuits and the inherent </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">uncertainly of litigation, we cannot predict how long it may take to resolve the pending lawsuits or the potential outcome or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">possible amount of any damages. As such, we currently are unable to reasonably estimate the possible losses or a range of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">possible losses that may result from these matters, if any. Expenses associated with the pending lawsuits and any potential </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related lawsuits could be material to our consolidated financial statements if we do not prevail in the defense of such </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">lawsuits, or even if we do prevail. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Indemnifications to Officers and Directors</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our corporate bylaws require that we indemnify our directors, as well as those who act as directors and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">officers of other entities at our request, against expenses, judgments, fines, settlements and other amounts actually and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:361.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reasonably incurred in connection with any proceedings arising out of their services to Geron. In addition, we have entered </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">into separate indemnification agreements with each of our directors and officers which provide for indemnification of these </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">directors and officers under similar circumstances and under additional circumstances. The indemnification obligations are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">more fully described in our bylaws and the indemnification agreements. We purchase standard insurance to cover claims or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">a portion of the claims made against our directors and officers. Since a maximum obligation is not explicitly stated in our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">bylaws or in our indemnification agreements and will depend on the facts and circumstances that arise out of any future </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">claims, the overall maximum amount of the obligations cannot be reasonably estimated.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Severance Plan</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We have adopted </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:193.35pt;position:var(--position);text-decoration:none;white-space:pre">two</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:208.34pt;position:var(--position);text-decoration:none;white-space:pre"> severance plans that apply to all of our employees who are not subject to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">performance improvement plans, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:193.34pt;position:var(--position);text-decoration:none;white-space:pre">one</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:207.77pt;position:var(--position);text-decoration:none;white-space:pre"> plan covering employees above the Senior Vice President level, i.e., executives, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">all other employees hired on or before December 31, 2021,, and the other plan covering all non-executive employees hired </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:517.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">on or after January 1, 2022. The severance plans provide for, among other benefits: (i) a severance payment upon a Change </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:529.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of Control Triggering Event and Separation from Service and (ii) a severance payment for each non‑executive employee </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:541.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">upon a Non‑Change of Control Triggering Event and Separation from Service. As defined in the severance plans, a Change </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of Control Triggering Event and Separation from Service requires a “double trigger” where: (i) an employee is terminated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">by us without cause in connection with a change of control or within </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:335.17pt;position:var(--position);text-decoration:none;white-space:pre">12 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:377.1pt;position:var(--position);text-decoration:none;white-space:pre"> following a change of control provided, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">however, that if an employee is terminated by us in connection with a change of control but immediately accepts </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employment with our successor or acquirer, the employee will not be eligible for the benefits outlined in the plans, (ii) an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employee resigns because in connection with a change of control, the offered terms of employment (new or continuing) by </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">us or our successor or acquirer within </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:211.42pt;position:var(--position);text-decoration:none;white-space:pre">30 days</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:242.24pt;position:var(--position);text-decoration:none;white-space:pre"> after the change of control results in a material change in the terms of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employment, or (iii) after accepting (or continuing) employment with us after a change of control, an employee resigns </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">within </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:86.53pt;position:var(--position);text-decoration:none;white-space:pre">12 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:128.45999999999998pt;position:var(--position);text-decoration:none;white-space:pre"> following a change of control due to a material change in the terms of employment. Under the severance </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:649.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">plans, a Non‑Change of Control Triggering Event and Separation from Service is defined as an event where an employee is </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:661.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">terminated by us without cause. Severance payments range from </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:318.75pt;position:var(--position);text-decoration:none;white-space:pre"><span style="-sec-ix-hidden:f-763">three</span></span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:338.71pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:351.48pt;position:var(--position);text-decoration:none;white-space:pre">18 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:393.41pt;position:var(--position);text-decoration:none;white-space:pre"> of base salary in connection with a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:673.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Change of Control Triggering Event or from six weeks to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:291.07pt;position:var(--position);text-decoration:none;white-space:pre">12 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:333pt;position:var(--position);text-decoration:none;white-space:pre"> of base salary in connection with a Non-Change of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Control Triggering Event, as well as a pro-rata portion of the employee’s annual target bonus, depending on the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employee’s position with us, payable in a lump sum payment, and monthly COBRA payments for the severance period. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The severance plans also provide that they shall not supersede the provisions of any individual employment agreements </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">entered into between us and our employees, and that the employees with such agreements will be entitled to whichever </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:733.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">benefits are greater under the severance plan or their employment agreement. A copy of the severance plan covering our </span></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">executive officers is filed as an exhibit to this Report. As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:299.05pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:377.59pt;position:var(--position);text-decoration:none;white-space:pre">, all our executive officers have </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employment agreements with severance provisions and will receive the greater severance benefits of their agreements or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">those in the severance plan applicable to them.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">In December 2025, we implemented a workforce reduction, representing approximately one-third of our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:126.7pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">workforce prior to the reduction in headcount. </span><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:245.53pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">See Note 16 on Restructuring for additional information.</span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:161.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Purchase Commitments</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:185.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We have engaged third‑party contract manufacturers to manufacture and supply additional quantities of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:197.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">RYTELO that meet applicable regulatory standards for current and potential future clinical trials and commercial uses. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:209.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Related to those contract manufacturing agreements, we have binding commercial purchase commitments of approximately </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:221.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">$16.7 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:112.35pt;position:var(--position);text-decoration:none;white-space:pre"> that can be cancelled, but would incur cancellation penalties, and approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:437.44pt;position:var(--position);text-decoration:none;white-space:pre">$43.3 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:491.29pt;position:var(--position);text-decoration:none;white-space:pre"> in agreed upon </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:233.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">manufacturing commitments that can be adjusted based on commercial demand of RYTELO. We expect to utilize all </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:245.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related commercial purchase commitments.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:269.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In the normal course of business, we enter into agreements with CROs for clinical trials for clinical and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:281.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">commercial supply manufacturing and with other vendors for non-clinical research studies, investigator-led trials and other </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:293.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">services and products for operating purposes. We have not considered these payments to be contractual obligations since </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:305.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the contracts are generally cancellable at any time by us upon less than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:343.93pt;position:var(--position);text-decoration:none;white-space:pre">180 days</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:379.75pt;position:var(--position);text-decoration:none;white-space:pre">’ prior written notice. We also have certain </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:317.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in-license agreements that require us to pay milestones to such third parties upon achievement of certain development, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:329.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">regulatory or commercial milestones. Amounts related to contingent milestone payments are not considered contractual </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:341.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">obligations as they are contingent on the successful achievement of certain development, regulatory approval and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:353.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">commercial milestones, which may not be achieved.</span></div> 2 3 3 3 2 3 3 1 2 1 P12M P30D P12M P18M P12M 16700000 43300000 P180D <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:68.5pt;position:var(--position);text-decoration:none;white-space:pre">OPERATING LEASES</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:401.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">New Jersey Office Space Lease</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:419.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">April 2019</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:175.92000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into an operating lease agreement for office space located at 3 Sylvan Way, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:431.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Parsippany, New Jersey, or the New Jersey Lease. The initial term of the New Jersey Lease is </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:435.82pt;position:var(--position);text-decoration:none;white-space:pre">11 years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:469.4pt;position:var(--position);text-decoration:none;white-space:pre"> with an option to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:443.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">extend for an additional </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:156.16pt;position:var(--position);text-decoration:none;white-space:pre">five years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:195.27pt;position:var(--position);text-decoration:none;white-space:pre"> and a </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:221.63pt;position:var(--position);text-decoration:none;white-space:pre">one-time option to terminate the New Jersey Lease without cause as of the 103rd </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:455.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">month anniversary of the commencement date of the lease</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:291.52pt;position:var(--position);text-decoration:none;white-space:pre">. The New Jersey Lease commenced on </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:452.43pt;position:var(--position);text-decoration:none;white-space:pre">October 1, 2019</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:517.11pt;position:var(--position);text-decoration:none;white-space:pre">, upon </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:467.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our control of the office space on that date. Based on the initial term of the New Jersey Lease of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:444.4pt;position:var(--position);text-decoration:none;white-space:pre">11 years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:477.98pt;position:var(--position);text-decoration:none;white-space:pre">, the right-of-use </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:479.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">asset and corresponding operating lease liability was approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:331.49pt;position:var(--position);text-decoration:none;white-space:pre">$2.4 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:380.34pt;position:var(--position);text-decoration:none;white-space:pre">, which represented the present value of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:491.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">lease payments over the initial lease term, net of a </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:260.69pt;position:var(--position);text-decoration:none;white-space:pre">seven</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:283.44pt;position:var(--position);text-decoration:none;white-space:pre">-month</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:312.31pt;position:var(--position);text-decoration:none;white-space:pre"> rent abatement period, using an incremental borrowing rate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:503.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:69.33pt;position:var(--position);text-decoration:none;white-space:pre">8%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:82.66pt;position:var(--position);text-decoration:none;white-space:pre"> based on information available as of October 1, 2019. As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:326.88pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:405.42pt;position:var(--position);text-decoration:none;white-space:pre">, the New Jersey Lease makes up </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:515.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">$1.3 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:107.35pt;position:var(--position);text-decoration:none;white-space:pre"> of our total right-of-use asset balance. Under the New Jersey Lease, we are also obligated to pay certain </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:527.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">variable expenses separately from the base rent, including electricity and common area maintenance. Such costs are being </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:539.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expensed in the period they are incurred. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:569.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">California Office Space Lease</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:587.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">October 2019</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:187.01pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into an operating lease agreement for office space located at 919 East </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:599.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Hillsdale Boulevard, Foster City, California, or the Foster City Lease. The initial term of the Foster City Lease is </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:512.0899999999999pt;position:var(--position);text-decoration:none;white-space:pre">87 </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:611.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:87.93pt;position:var(--position);text-decoration:none;white-space:pre"> with an option to extend for an additional </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:258.59000000000003pt;position:var(--position);text-decoration:none;white-space:pre">five years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:297.7pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:635.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The Foster City Lease commenced on </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:275.75pt;position:var(--position);text-decoration:none;white-space:pre">March 10, 2020</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:339.33000000000004pt;position:var(--position);text-decoration:none;white-space:pre">, upon the substantial completion of all tenant </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:647.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">improvements. As of the lease commencement date, the right-of-use asset and corresponding operating lease liability was </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:659.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:118.7pt;position:var(--position);text-decoration:none;white-space:pre">$3.4 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:167.55pt;position:var(--position);text-decoration:none;white-space:pre">, which represented the present value of remaining lease payments using an incremental </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:671.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">borrowing rate of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:130.94pt;position:var(--position);text-decoration:none;white-space:pre">7%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:144.26999999999998pt;position:var(--position);text-decoration:none;white-space:pre"> over the initial lease term of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:261.59000000000003pt;position:var(--position);text-decoration:none;white-space:pre">87 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:303.52pt;position:var(--position);text-decoration:none;white-space:pre">, net of a </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:340.98pt;position:var(--position);text-decoration:none;white-space:pre">three</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:360.94pt;position:var(--position);text-decoration:none;white-space:pre">-month</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:389.81pt;position:var(--position);text-decoration:none;white-space:pre"> rent abatement period. As of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:683.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:137.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, the Foster City Lease makes up </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:270.22pt;position:var(--position);text-decoration:none;white-space:pre">$0.9 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:319.07pt;position:var(--position);text-decoration:none;white-space:pre"> of our total right-of-use asset balance. Under the Foster </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:695.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">City Lease, we are also obligated to pay certain variable expenses separately from the base rent, including taxes and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:707.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common area maintenance. Such costs are considered non-lease components and have been excluded from the calculation </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:719.9pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of the right-of-use asset and corresponding operating lease liability and are being expensed in the period they are incurred. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The components of lease costs included in selling, general and administrative expenses on our consolidated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements of operations for the New Jersey Lease, and the Foster City Lease were as follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:143.25pt;position:var(--position);width:325.5pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:99pt"></td><td style="padding:0;width:8.25pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);width:215.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:62.78pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:99pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating lease costs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:25.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,014<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:25.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:43.04pt"></span></span><span style="left:50.67pt;position:var(--position)">987<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:25.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:43.04pt"></span></span><span style="left:50.67pt;position:var(--position)">962<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Variable lease costs</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:40.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">285<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:40.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">261<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:40.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">344<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total lease costs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,299<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,248<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,306<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:197pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The undiscounted future non-cancellable lease payments under the New Jersey Lease and the Foster City </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:209pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Lease as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:105.93pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:184.47pt;position:var(--position);text-decoration:none;white-space:pre"> were as follows (in thousands):</span></div><div style="position:var(--position);top:233pt;width:612pt"><div style="font-size:0pt;left:199.12pt;position:var(--position);width:213.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:144pt"></td><td style="padding:0;width:69.75pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2026</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,040<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2027</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:15pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">716<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2028</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:30pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">376<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2029</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:45pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">383<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2030</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:60pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">293<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:75pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Thereafter</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:75pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:90pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total lease payments</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:90pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:40.54pt"></span></span><span style="left:43.17pt;position:var(--position)">2,808<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:105pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: imputed interest</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:105pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(363)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:120pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:120pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">2,445<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:145.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:224.48000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, the weighted average remaining lease term in years and the weighted average </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">discount rate under the New Jersey Lease and the Foster City Lease were </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:353.4pt;position:var(--position);text-decoration:none;white-space:pre">3.5 years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:389.48pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:408.91pt;position:var(--position);text-decoration:none;white-space:pre">5.1%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:429.74pt;position:var(--position);text-decoration:none;white-space:pre">, respectively.</span></div> P11Y P5Y P11Y P11Y 2400000 2400000 P7M 0.08 1300000 P87M P5Y 3400000 0.07 P87M P3M 900000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The components of lease costs included in selling, general and administrative expenses on our consolidated </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statements of operations for the New Jersey Lease, and the Foster City Lease were as follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:143.25pt;position:var(--position);width:325.5pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:99pt"></td><td style="padding:0;width:8.25pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);width:215.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:62.78pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:99pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating lease costs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:25.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,014<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:25.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:43.04pt"></span></span><span style="left:50.67pt;position:var(--position)">987<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:25.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:43.04pt"></span></span><span style="left:50.67pt;position:var(--position)">962<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Variable lease costs</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:40.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">285<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:40.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">261<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:40.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">344<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total lease costs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:107.25pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,299<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:180pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,248<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:252.75pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,306<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 1014000 987000 962000 285000 261000 344000 1299000 1248000 1306000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The undiscounted future non-cancellable lease payments under the New Jersey Lease and the Foster City </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:209pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Lease as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:105.93pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:184.47pt;position:var(--position);text-decoration:none;white-space:pre"> were as follows (in thousands):</span></div><div style="position:var(--position);top:233pt;width:612pt"><div style="font-size:0pt;left:199.12pt;position:var(--position);width:213.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:144pt"></td><td style="padding:0;width:69.75pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2026</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">1,040<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2027</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:15pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">716<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2028</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:30pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">376<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2029</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:45pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">383<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2030</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:60pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">293<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:75pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Thereafter</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:75pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:90pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total lease payments</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:90pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:40.54pt"></span></span><span style="left:43.17pt;position:var(--position)">2,808<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:105pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: imputed interest</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:105pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(363)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:120pt;width:144pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:144pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:144pt;position:var(--position);top:120pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">2,445<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 1040000 716000 376000 383000 293000 0 2808000 363000 2445000 P3Y6M 0.051 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">DEBT</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Hercules Loan Agreement</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">September 30, 2020</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:216.44pt;position:var(--position);text-decoration:none;white-space:pre">, we, Hercules Capital, Inc., or Hercules, and Silicon Valley Bank, or SVB, entered </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">into a term loan facility, or the Term Loan, for up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:269.36pt;position:var(--position);text-decoration:none;white-space:pre">$75.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:323.21pt;position:var(--position);text-decoration:none;white-space:pre">, which was amended in August 2021, or the Original </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Loan Agreement. On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:145.63pt;position:var(--position);text-decoration:none;white-space:pre">June 30, 2022</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:201.45pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into a second amendment to the Original Loan Agreement. Under the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">second amendment, the aggregate principal amount available to us increased from </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:389.17pt;position:var(--position);text-decoration:none;white-space:pre">$75.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:443.02pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:455.79pt;position:var(--position);text-decoration:none;white-space:pre">$125.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:514.64pt;position:var(--position);text-decoration:none;white-space:pre">, with </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:517pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">such principal being available in a series of tranches, subject to certain terms and conditions. Over the course of the Term </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:529pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Loan, we had drawn down a total of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:205.31pt;position:var(--position);text-decoration:none;white-space:pre">$80.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:259.15999999999997pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">All obligations outstanding under the Hercules Loan Agreement, amounting to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:438.67pt;position:var(--position);text-decoration:none;white-space:pre">$86.5 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:492.52pt;position:var(--position);text-decoration:none;white-space:pre">, were repaid </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in full on </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:97.64pt;position:var(--position);text-decoration:none;white-space:pre">November 1, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:172.32pt;position:var(--position);text-decoration:none;white-space:pre">, upon which the Hercules Loan Agreement was terminated and all liens on our assets granted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in connection with the Hercules Loan Agreement were released.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Pharmakon Loan Agreement</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">November 1, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:210.9pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into a loan agreement, or the Pharmakon Loan Agreement, with </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">BioPharma Credit Investments V (Master) LP and BPCR Limited Partnership, each, a Lender, which are investment funds </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">managed by Pharmakon Advisors, LP, and BioPharma Credit PLC, as collateral agent, that provides for a </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:483.06pt;position:var(--position);text-decoration:none;white-space:pre">5</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:488.06pt;position:var(--position);text-decoration:none;white-space:pre">-year senior </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">secured term loan facility of up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:196.38pt;position:var(--position);text-decoration:none;white-space:pre">$250.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:255.23pt;position:var(--position);text-decoration:none;white-space:pre">, divided into three committed tranches: (i) a Tranche A Loan in an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">aggregate principal amount of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:181.12pt;position:var(--position);text-decoration:none;white-space:pre">$125.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:239.97pt;position:var(--position);text-decoration:none;white-space:pre">, or the Tranche A Loan, which was funded on November 1, 2024, or the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Tranche A Closing Date; (ii) a Tranche B Loan in an aggregate principal amount of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:395.01pt;position:var(--position);text-decoration:none;white-space:pre">$75.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:448.86pt;position:var(--position);text-decoration:none;white-space:pre">, or the Tranche B Loan, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">which is available, subject to certain limited conditions, at our option; and (iii) a Tranche C Loan in an aggregate principal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">amount of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:101.8pt;position:var(--position);text-decoration:none;white-space:pre">$50.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:155.65pt;position:var(--position);text-decoration:none;white-space:pre">, or the Tranche C Loan, and together with the Tranche A Loan and the Tranche B Loan, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">collectively, the Term Loans, which is available to us upon reaching a specified trailing twelve-month RYTELO revenue </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:727pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">milestone. The Tranche B Loan and the Tranche C Loan, once available, could have been requested on or prior to </span></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025. A portion of the proceeds from the Tranche A Loan were used to repay, in full, all amounts owed </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">under the Hercules Loan Agreement, which was terminated effective </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:336.45pt;position:var(--position);text-decoration:none;white-space:pre">November 1, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:411.13pt;position:var(--position);text-decoration:none;white-space:pre">. The remaining proceeds will be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">used to fund our general corporate and working capital requirements.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:109.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On January 5, 2026, the Pharmakon Loan Agreement was amended to extend the date for requesting the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Tranche B Loan and Tranche C Loan, once available, from December 31, 2025 to July 30, 2026. The amendment also </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">extended the Makewhole Date from November 1, 2026 to May 1, 2027.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The Term Loans mature on </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:233.31pt;position:var(--position);text-decoration:none;white-space:pre">November 1, 2029</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:307.99pt;position:var(--position);text-decoration:none;white-space:pre">. The Term Loans bear interest at a variable rate per annum </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">equal to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:92.9pt;position:var(--position);text-decoration:none;white-space:pre">5.75%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:118.72999999999999pt;position:var(--position);text-decoration:none;white-space:pre"> plus the three-month Secured Overnight Financing Rate, or SOFR, with a </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:417.89pt;position:var(--position);text-decoration:none;white-space:pre"><span style="-sec-ix-hidden:f-822">SOFR</span></span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:442.89pt;position:var(--position);text-decoration:none;white-space:pre"> floor of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:478.15pt;position:var(--position);text-decoration:none;white-space:pre">3.00%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:503.98pt;position:var(--position);text-decoration:none;white-space:pre">. As of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">inception of the Tranche A Loan, the interest rate applicable to the Tranche A Loan was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:412.73pt;position:var(--position);text-decoration:none;white-space:pre">10.32%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:443.56pt;position:var(--position);text-decoration:none;white-space:pre">. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:448.56pt;position:var(--position);text-decoration:none;white-space:pre">As of December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:193.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025, the applicable interest rate was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:209.12pt;position:var(--position);text-decoration:none;white-space:pre">11.13%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:239.95pt;position:var(--position);text-decoration:none;white-space:pre">. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:244.95pt;position:var(--position);text-decoration:none;white-space:pre">Interest is due and payable quarterly on the last day of each quarter. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:205.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Pharmakon Loan Agreement requires we pay an amount equal to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:320.99pt;position:var(--position);text-decoration:none;white-space:pre">2.50%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:346.82pt;position:var(--position);text-decoration:none;white-space:pre"> of the Lenders’ total committed amount to fund </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the Term Loans, payable with respect to each Term Loan on the funding date of such Term Loan.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We may elect to prepay the Term Loans in part or in whole prior to the Maturity Date with such </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">prepayments being subject to a prepayment premium equal to the principal amount so prepaid multiplied by </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:492.44pt;position:var(--position);text-decoration:none;white-space:pre">3%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:505.77pt;position:var(--position);text-decoration:none;white-space:pre"> if made </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">prior to the 3rd anniversary of the funding date of the applicable Term Loan, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:367.32pt;position:var(--position);text-decoration:none;white-space:pre">2%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:380.65pt;position:var(--position);text-decoration:none;white-space:pre"> if made on or after the 3rd anniversary of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the funding date of the applicable Term Loan but prior to the 4th anniversary of the funding date of the applicable Term </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Loan, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:100.96000000000001pt;position:var(--position);text-decoration:none;white-space:pre">1%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:114.28999999999999pt;position:var(--position);text-decoration:none;white-space:pre"> if made on or after the 4th anniversary of the funding date of the applicable Term Loan but prior to the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Maturity Date. In addition to the prepayment premium, prepayments of any Term Loan prior to the 2nd anniversary of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">funding date of such Term Loan are subject to a make-whole amount equal to the sum of all interest that would have </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">accrued through such 2nd anniversary.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our obligations under the Pharmakon Loan Agreement are secured by substantially all of our assets, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:355.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">including our intellectual property. Certain of our subsidiaries may, from time to time after the Tranche A Closing Date, be </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">required to guarantee our obligations under the Pharmakon Loan Agreement and, in connection with such guarantee, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">pledge substantially all of their assets, including intellectual property, to secure such guarantee.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The Pharmakon Loan Agreement contains customary affirmative and restrictive covenants and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">representations and warranties. We and our subsidiaries are bound by certain affirmative covenants setting forth actions </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:427.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">that are required during the term of the Pharmakon Loan Agreement, including, without limitation, certain information </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:439.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">delivery requirements, obligations to maintain certain insurance, and certain notice requirements. There are no financial </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">covenants. Additionally, we and our subsidiaries are bound by certain restrictive covenants setting forth actions that are not </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">permitted to be taken during the term of the Pharmakon Loan Agreement, including, without limitation, (i) selling or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">disposing of assets, (ii) amending, modifying or waiving our rights under material agreements, (iii) consummating change </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in control transactions unless all amounts becoming due under the Loan Agreement are paid in full immediately upon (and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">concurrent with) the consummation of any such change in control transaction, (iv) incurring additional indebtedness, (v) </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">incurring non-permitted liens or encumbrance on our or our subsidiaries’ assets, (vi) paying dividends or making any </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">distribution or payment on or redeeming, retiring or purchasing any equity interests, and (vii) making payments on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">subordinated indebtedness, in each case, subject to specified exceptions. The Pharmakon Loan Agreement also contains the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:547.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">following events of default: (i) failure to pay principal, interest and other amounts when due, (ii) the breach of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">covenants under the Loan Agreement, (iii) the occurrence of a material adverse change or the occurrence of a withdrawal </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:571.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">event in respect of RYTELO, (iv) certain attachments of the credit parties assets and restraints on their business, (v) certain </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">insolvency, liquidation, bankruptcy or similar events, (vi) certain cross-default of third-party indebtedness and royalty </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">revenue contracts, (vii) the failure to pay certain judgments, (viii) material misrepresentations, (ix) the loan documents </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ceasing to create a valid security interest in a material portion of the collateral, (x) the occurrence of certain ERISA events </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and (xi) the occurrence of a default under any subordination or intercreditor agreement, in each case subject to the grace </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">periods, cure period and thresholds as specified in the Pharmakon Loan Agreement. Upon the occurrence and during the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">continuance of an event of default, the Lenders may, among other things, accelerate our obligations under the Pharmakon </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Loan Agreement (including all obligations for principal, interest and any applicable make-whole and prepayment </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">premiums); provided that upon an event of default relating to certain insolvency, liquidation, bankruptcy or similar events, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">all outstanding obligations will be immediately accelerated. As of December 31, 2025, we were in compliance with our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Pharmakon Loan Agreement covenants.</span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Future Minimum Payments</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents future minimum payments, including interest and the end of term charge, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">under the Term Loan as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:167.26999999999998pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:245.81pt;position:var(--position);text-decoration:none;white-space:pre"> (in thousands):</span></div><div style="position:var(--position);top:121.5pt;width:612pt"><div style="font-size:0pt;left:161.62pt;position:var(--position);width:288.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:219pt"></td><td style="padding:0;width:69.75pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">3,110<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2026</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:15pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">12,338<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2027</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:30pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">12,338<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2028</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:45pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">12,372<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2029</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:60pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">135,310<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:75pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Thereafter</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:75pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:90pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:90pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">175,468<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:105pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: amount representing interest</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:105pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:32.21pt"></span></span><span style="left:34.84pt;position:var(--position)">(50,468)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:120pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: unamortized debt discount and issuance costs</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:120pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:37.21pt"></span></span><span style="left:39.84pt;position:var(--position)">(5,453)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:135pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Noncurrent portion of debt</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:135pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:33.17pt;position:var(--position)">119,547<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:300.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Liabilities Related to Sale of Future Royalties</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:324.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">November 1, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:210.9pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into a revenue participation right purchase and sale agreement, or the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:336.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Royalty Pharma Agreement, with Royalty Pharma Development Funding, LLC, or Royalty Pharma. Pursuant to the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:348.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Royalty Pharma Agreement, we received an upfront payment of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:317.09pt;position:var(--position);text-decoration:none;white-space:pre">$125.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:375.94pt;position:var(--position);text-decoration:none;white-space:pre">, or the Purchase Price, in exchange for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:360.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">which Royalty Pharma obtained the right, or the Revenue Participation Right, to receive certain amounts calculated as a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:372.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">percentage of future U.S. net sales of RYTELO for each calendar quarter, or Royalty Payments, during the term </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:384.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">contemplated by the Royalty Pharma Agreement. Specifically, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:311.22pt;position:var(--position);text-decoration:none;white-space:pre">the revenue participation rate commences at </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:489.82pt;position:var(--position);text-decoration:none;white-space:pre">7.75%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:515.65pt;position:var(--position);text-decoration:none;white-space:pre"> for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:396.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">annual U.S. net sales of up to and equal to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:229.45pt;position:var(--position);text-decoration:none;white-space:pre">$500.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:288.3pt;position:var(--position);text-decoration:none;white-space:pre"> declining to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:340.74pt;position:var(--position);text-decoration:none;white-space:pre">1.0%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:361.57pt;position:var(--position);text-decoration:none;white-space:pre"> for annual U.S. net sales exceeding </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:507.24pt;position:var(--position);text-decoration:none;white-space:pre">$1.0 billion</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:553.3199999999999pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:408.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">until the date when the aggregate Royalty Payments equal or exceed </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:333.97pt;position:var(--position);text-decoration:none;white-space:pre">1.65</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:351.47pt;position:var(--position);text-decoration:none;white-space:pre"> times the Purchase Price, if this occurs by June </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:420.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">30, 2031 or the date when the aggregate Royalty Payments equal or exceed </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:361.49pt;position:var(--position);text-decoration:none;white-space:pre">2.0</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:373.99pt;position:var(--position);text-decoration:none;white-space:pre"> times the Purchase Price.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:444.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In addition, we have the option to repurchase all of the Revenue Participation Right from Royalty Pharma </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:456.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">for a purchase price of equal to the Buy-Out-Payment, as defined below, if we entered into a definitive agreement to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:468.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consummate a change of control, or Buy-Back Option.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:492.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">“Buy-Out Payment” means an amount equal to (a) </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:325.71000000000004pt;position:var(--position);text-decoration:none;white-space:pre">1.65</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:343.21000000000004pt;position:var(--position);text-decoration:none;white-space:pre"> times the Purchase Price minus the aggregate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:504.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Royalty Payments as of the change of control, if the change of control occurs on or prior to December 31, 2027, or (b) </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:533.61pt;position:var(--position);text-decoration:none;white-space:pre">2.0</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:546.11pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:516.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">times the Purchase Price minus the aggregate Royalty Payments as of the change of control, if the change of control occurs </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:528.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">after December 31, 2027.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:552.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We accounted for the Royalty Pharma Agreement as a financing liability, primarily because it has </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:564.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">significant continuing involvement in generating the future revenue on which the Royalty Payments are based. The liability </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:576.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">related to Revenue Participation Right and the related interest expense are measured based on our current estimate of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:588.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">timing and amount of expected future Royalty Payments expected to be paid over the estimated term of the Royalty </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:600.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Pharma Agreement using a discounted cash flow model. The liability is amortized using the effective interest rate method, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:612.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">resulting in recognition of interest expense over the estimated term of the agreement.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:636.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We have determined the fair value of the liability related to the sale of future royalties is based on our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:648.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">current estimates of future royalties expected to be paid to Royalty Pharma over the life of the arrangement, which are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:660.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">considered Level 3.</span></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table shows the activity within the liability related to sale of future royalties during the year </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:84.86pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:163.4pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:336pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:156pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);width:156pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.96pt;position:var(--position);text-decoration:none;white-space:pre">Liability Related to Sale of Future Royalties</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:336pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Carrying value of liability related to sale of future royalties at December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:25.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:111.79pt"></span></span><span style="left:119.42pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Non-cash interest expense recognized</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:40.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:121.79pt"></span></span><span style="left:124.42pt;position:var(--position)">18,948<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Royalty payments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:55.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:118.46pt"></span></span><span style="left:121.08999999999999pt;position:var(--position)">(14,159)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Carrying value of liability related to sale of future royalties at December 31, 2025</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:70.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:111.79pt"></span></span><span style="left:119.42pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:212pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Embedded Derivatives</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:230pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The conditional exercisable call option related to the event of default is considered to be an embedded </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:242pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">derivative which is required to be bifurcated and accounted for as a separate financial instrument. In the periods presented, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:254pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the value of the embedded derivative is not material and therefore, no amount has been recognized. If an event of default </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:266pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">becomes more probable than is currently estimated, then the embedded derivative could become material in future periods </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:278pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and would be recognized as a separate financial instrument at that time. The embedded derivatives are classified within </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:290pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Level 3 of the fair value hierarchy due to the use of significant unobservable inputs.</span></div> 75000000.0 75000000.0 125000000.0 80000000.0 86500000 P5Y 250000000.0 125000000.0 75000000.0 50000000.0 0.0575 0.0300 0.1032 0.1113 0.0250 0.03 0.02 0.01 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents future minimum payments, including interest and the end of term charge, </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">under the Term Loan as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:167.26999999999998pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:245.81pt;position:var(--position);text-decoration:none;white-space:pre"> (in thousands):</span></div><div style="position:var(--position);top:121.5pt;width:612pt"><div style="font-size:0pt;left:161.62pt;position:var(--position);width:288.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:219pt"></td><td style="padding:0;width:69.75pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">3,110<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2026</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:15pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">12,338<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2027</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:30pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">12,338<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2028</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:45pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">12,372<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2029</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:60pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">135,310<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:75pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Thereafter</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:75pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:90pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:90pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">175,468<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:105pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: amount representing interest</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:105pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:32.21pt"></span></span><span style="left:34.84pt;position:var(--position)">(50,468)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:120pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: unamortized debt discount and issuance costs</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:120pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:37.21pt"></span></span><span style="left:39.84pt;position:var(--position)">(5,453)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:135pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Noncurrent portion of debt</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:219pt;position:var(--position);top:135pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:33.17pt;position:var(--position)">119,547<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 3110000 12338000 12338000 12372000 135310000 0 175468000 50468000 5453000 119547000 125000000.0 0.0775 500000000.0 0.010 1000000000.0 1.65 2.0 1.65 2.0 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table shows the activity within the liability related to sale of future royalties during the year </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:84.86pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:163.4pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:336pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:156pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);width:156pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.96pt;position:var(--position);text-decoration:none;white-space:pre">Liability Related to Sale of Future Royalties</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:336pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Carrying value of liability related to sale of future royalties at December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:25.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:111.79pt"></span></span><span style="left:119.42pt;position:var(--position)">124,793<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Non-cash interest expense recognized</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:40.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:121.79pt"></span></span><span style="left:124.42pt;position:var(--position)">18,948<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Royalty payments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:55.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:118.46pt"></span></span><span style="left:121.08999999999999pt;position:var(--position)">(14,159)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:336pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:336pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Carrying value of liability related to sale of future royalties at December 31, 2025</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:339pt;position:var(--position);top:70.5pt;width:156pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:156pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:111.79pt"></span></span><span style="left:119.42pt;position:var(--position)">129,582<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 124793000 18948000 14159000 129582000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">STOCKHOLDERS’ EQUITY</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:338pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Authorized Common Stock</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:356pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In May 2023, our stockholders approved an amendment to our Restated Certificate of Incorporation to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:368pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">increase the total number of authorized shares of common stock from </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:338.46pt;position:var(--position);text-decoration:none;white-space:pre">675,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:388.46pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:401.23pt;position:var(--position);text-decoration:none;white-space:pre">1,350,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:458.73pt;position:var(--position);text-decoration:none;white-space:pre"> shares.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:398pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Public Offerings</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:416pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">January 10, 2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:204.8pt;position:var(--position);text-decoration:none;white-space:pre">, we completed an underwritten public offering consisting of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:449.54pt;position:var(--position);text-decoration:none;white-space:pre">68,007,741</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:494.54pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:428pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common stock and the 2023 pre-funded warrants. All of the securities were issued separately. The public offering price of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:440pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the common stock was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:152.3pt;position:var(--position);text-decoration:none;white-space:pre">$2.45</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:174.8pt;position:var(--position);text-decoration:none;white-space:pre"> per share. The public offering price of the 2023 pre-funded warrant was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:466.72pt;position:var(--position);text-decoration:none;white-space:pre">$2.449</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:494.22pt;position:var(--position);text-decoration:none;white-space:pre"> per share. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:452pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The net cash proceeds from this offering were </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:244.95pt;position:var(--position);text-decoration:none;white-space:pre">$213.3 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:303.8pt;position:var(--position);text-decoration:none;white-space:pre">, after deducting the underwriting discount and other offering </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:464pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expenses paid by us, and excluded any future proceeds from the exercise of the 2023 pre-funded warrant. As of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:476pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:137.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, all 2023 pre-funded warrants have been exercised.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:500pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">March 21, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:199.8pt;position:var(--position);text-decoration:none;white-space:pre">, we completed an underwritten public offering of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:401.52pt;position:var(--position);text-decoration:none;white-space:pre">41,999,998</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:446.52pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:512pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock and pre-funded warrants to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:230.55pt;position:var(--position);text-decoration:none;white-space:pre">8,002,668</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:270.55pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock, or the 2024 pre-funded warrants. All of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:524pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the securities were issued separately. The public offering price of the common stock was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:415.56pt;position:var(--position);text-decoration:none;white-space:pre">$3.00</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:438.06pt;position:var(--position);text-decoration:none;white-space:pre"> per share. The public </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:536pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">offering price of the 2024 pre-funded warrants was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:264.97pt;position:var(--position);text-decoration:none;white-space:pre">$2.99</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:287.47pt;position:var(--position);text-decoration:none;white-space:pre"> per share. The net cash proceeds from the March 2024 offering </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:548pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">were approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:140.61pt;position:var(--position);text-decoration:none;white-space:pre">$141.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:199.46pt;position:var(--position);text-decoration:none;white-space:pre">, after deducting the underwriting discount and other offering expenses paid by us, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:560pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">excluding any future proceeds from the exercise of the pre-funded warrants. As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:389.26pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:467.8pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:472.8pt;position:var(--position);text-decoration:none;white-space:pre">5.4 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:516.65pt;position:var(--position);text-decoration:none;white-space:pre"> of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:572pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2024 pre-funded warrants have been exercised and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:264.11pt;position:var(--position);text-decoration:none;white-space:pre">2.6 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:307.96000000000004pt;position:var(--position);text-decoration:none;white-space:pre"> were outstanding. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:596pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:145.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:224.48000000000002pt;position:var(--position);text-decoration:none;white-space:pre"> and</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:241.41pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:243.91pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:263.90999999999997pt;position:var(--position);text-decoration:none;white-space:pre">,</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:266.40999999999997pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:268.90999999999997pt;position:var(--position);text-decoration:none;white-space:pre">pre-funded warrants to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:400.44pt;position:var(--position);text-decoration:none;white-space:pre">29,053,145</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:445.44pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:464.87pt;position:var(--position);text-decoration:none;white-space:pre">59,433,145</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:509.87pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:512.37pt;position:var(--position);text-decoration:none;white-space:pre">shares of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:608pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our common stock, respectively, remained outstanding and were associated with the May 2020, April 2022 and March </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:620pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2024 public offerings. These warrants have an exercise price of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:314.59pt;position:var(--position);text-decoration:none;white-space:pre">$0.001</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:342.09pt;position:var(--position);text-decoration:none;white-space:pre"> per share and no expiration date.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:650pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Upon the issuance of the 2023 and 2024 pre-funded warrants, we evaluated the warrant terms to determine </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:662pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the appropriate accounting and classification pursuant to FASB Accounting Standards Codification Topic 480, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:674pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Distinguishing Liabilities from Equity</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:210.3pt;position:var(--position);text-decoration:none;white-space:pre">, and FASB Accounting Standards Codification Topic 815, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:448.99pt;position:var(--position);text-decoration:none;white-space:pre">Derivatives and Hedging</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:549.44pt;position:var(--position);text-decoration:none;white-space:pre">. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:686pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Warrants are classified as liabilities when the warrant terms allow settlement of the warrant exercise in cash and classified </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:698pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">as equity when the warrant terms only allow settlement in shares of common stock. The terms of the 2023 and 2024 pre-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:710pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">funded warrants include certain provisions related to fundamental transactions and a cashless exercise provision in the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:722pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">event registered shares are not available, and do not include any mandatory redemption provisions. Based on our </span></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">evaluation, we concluded the 2023 and 2024 pre-funded warrants should be classified as equity with no subsequent </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">remeasurement as long as such warrants continue to be classified as equity.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Warrant Exercises</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For the year ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:198.64pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:277.18pt;position:var(--position);text-decoration:none;white-space:pre">, warrants were exercised to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:429.48pt;position:var(--position);text-decoration:none;white-space:pre">1,162,376</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:469.48pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common stock </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:119.56pt;position:var(--position);text-decoration:none;white-space:pre">at an exercise price of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:209.69pt;position:var(--position);text-decoration:none;white-space:pre">$1.30</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:232.19pt;position:var(--position);text-decoration:none;white-space:pre"> per share </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:273.53pt;position:var(--position);text-decoration:none;white-space:pre">for net cash proceeds of approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:431.68pt;position:var(--position);text-decoration:none;white-space:pre">$1.5 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:480.53pt;position:var(--position);text-decoration:none;white-space:pre">, which proceeds </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:145.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">were received in January 2026. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:185.57999999999998pt;position:var(--position);text-decoration:none;white-space:pre">The warrants were issued in connection with underwritten public offerings of common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock in May 2020.  The remaining warrants </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:238.61pt;position:var(--position);text-decoration:none;white-space:pre">to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:286.89pt;position:var(--position);text-decoration:none;white-space:pre">240,146</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:319.39pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock expired on December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:169.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025 and are no longer outstanding.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For the </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:152.59pt;position:var(--position);text-decoration:none;white-space:pre">year</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:169.78pt;position:var(--position);text-decoration:none;white-space:pre"> ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:198.64pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:277.18pt;position:var(--position);text-decoration:none;white-space:pre">, warrants to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:367.36pt;position:var(--position);text-decoration:none;white-space:pre">1,071,981</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:407.36pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock at an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exercise price of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:127pt;position:var(--position);text-decoration:none;white-space:pre">$1.30</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:149.5pt;position:var(--position);text-decoration:none;white-space:pre"> per share were exercised for net cash proceeds of approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:411.11pt;position:var(--position);text-decoration:none;white-space:pre">$1.4 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:459.96pt;position:var(--position);text-decoration:none;white-space:pre">. The warrants were </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">issued in connection with an underwritten public offering of common stock in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:372.64pt;position:var(--position);text-decoration:none;white-space:pre">May 2020. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:418.46pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:442.9pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:521.44pt;position:var(--position);text-decoration:none;white-space:pre">, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">warrants to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:143.68pt;position:var(--position);text-decoration:none;white-space:pre">1,402,522</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:183.68pt;position:var(--position);text-decoration:none;white-space:pre"> shares</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:211.15pt;position:var(--position);text-decoration:none;white-space:pre"> of our common stock remained outstanding.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2023 Sales Agreement</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">November 1, 2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:210.9pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into an At Market Issuance Sales Agreement, or the 2023 Sales </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Agreement, with B. Riley, pursuant to which we could issue and sell shares of our common stock having an aggregate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">offering price of up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:149.25pt;position:var(--position);text-decoration:none;white-space:pre">$100 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:200.6pt;position:var(--position);text-decoration:none;white-space:pre">. We have agreed to pay B. Riley an aggregate commission rate equal to up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:514.1pt;position:var(--position);text-decoration:none;white-space:pre">3.0%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:534.9300000000001pt;position:var(--position);text-decoration:none;white-space:pre"> of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:307.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the gross proceeds of the sales price per share for common stock sold under the 2023 Sales Agreement. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:473.36pt;position:var(--position);text-decoration:none;white-space:pre">No</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:485.58pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common stock were sold pursuant to the 2023 Sales Agreement, which was terminated </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:408.14pt;position:var(--position);text-decoration:none;white-space:pre">in January 2026. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Equity Plans</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:355.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2011 Incentive Award Plan</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In May 2011, our stockholders approved the adoption of the 2011 Incentive Award Plan, or 2011 Plan. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2011 Plan provided for grants of either incentive stock options or nonstatutory stock options and stock purchase rights to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employees (including officers and employee directors) and consultants (including non‑employee directors). Upon the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:409.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">adoption of the 2018 Equity Incentive Plan in May 2018 (see below), no further grants of stock options or stock purchase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">rights were made under the 2011 Plan. Stock options granted under the 2011 Plan expire no later than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:467.28pt;position:var(--position);text-decoration:none;white-space:pre">ten years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:503.06pt;position:var(--position);text-decoration:none;white-space:pre"> from the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">date of grant. Stock option exercise prices were equal to the fair market value of the underlying common stock on the date </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of grant.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Service‑based stock options under the 2011 Plan generally vested over a period of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:452.08pt;position:var(--position);text-decoration:none;white-space:pre">four years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:492.32pt;position:var(--position);text-decoration:none;white-space:pre"> from the date </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of grant. Other stock awards (restricted stock awards and restricted stock units) had variable vesting schedules which were </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:493.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">determined by our board of directors on the date of grant. All outstanding awards granted under the 2011 Plan remain </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:505.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">subject to the terms of the 2011 Plan and the individual award agreements thereunder.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:535.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2018 Equity Incentive Plan</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:559.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.22pt;position:var(--position);text-decoration:none;white-space:pre">May 15, 2018</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:192.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, our stockholders approved the adoption of the 2018 Equity Incentive Plan, or 2018 Plan, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:571.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">as the successor to the 2011 Plan. The 2018 Plan provides for the grant of incentive stock options, nonstatutory stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:583.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">options, stock appreciation rights, restricted stock awards, restricted stock unit awards, other stock awards, and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:595.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">performance awards that may be settled in cash, stock, or other property. Eligible participants under the 2018 Plan include </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:607.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our employees, consultants and non-employee directors. The number of shares reserved for issuance under the 2018 Plan </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:619.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(subject to adjustment for certain changes in capitalization) is equal to the sum of (i) the unallocated shares of common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:631.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock remaining available for future grants under the 2011 Plan as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:335.43pt;position:var(--position);text-decoration:none;white-space:pre">May 15, 2018</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:391.25pt;position:var(--position);text-decoration:none;white-space:pre">, (ii) </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:410.95pt;position:var(--position);text-decoration:none;white-space:pre">10,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:455.95pt;position:var(--position);text-decoration:none;white-space:pre"> newly reserved shares </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:643.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">of common stock and (iii) the number of shares subject to awards granted under the 2002 Equity Incentive Plan, and the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:655.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2011 Plan as such shares become available from time to time, referred to as the Prior Plans’ Returning Shares. Such Prior </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:667.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Plans’ Returning Shares become available for issuance under the 2018 Plan if outstanding stock awards granted under the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:679.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2002 Equity Incentive Plan and the 2011 Plan, after </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:267.74pt;position:var(--position);text-decoration:none;white-space:pre">May 15, 2018</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:323.56pt;position:var(--position);text-decoration:none;white-space:pre">, expire or terminate for any reason prior to exercise or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:691.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">settlement or are forfeited, cancelled or otherwise returned to us because of the failure to meet a contingency or condition </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:703.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">required for the vesting of such shares, or, subject to certain exceptions, are reacquired or withheld (or not issued) by us to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:715.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">satisfy a tax withholding obligation in connection with a stock award. In May 2025 and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:410.39pt;position:var(--position);text-decoration:none;white-space:pre">May 2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:451.21pt;position:var(--position);text-decoration:none;white-space:pre">, our stockholders </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:727.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">approved amendments to our 2018 Equity Incentive Plan to increase the total number of shares issuable under such plan by </span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">20,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.93pt;position:var(--position);text-decoration:none;white-space:pre">43,360,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:167.93pt;position:var(--position);text-decoration:none;white-space:pre">,shares of our common stock, respectively. As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:365.81pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:444.35pt;position:var(--position);text-decoration:none;white-space:pre">, an aggregate total of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">98,971,971</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> shares of common stock have been reserved under the 2018 Equity Incentive Plan, with </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:458.7pt;position:var(--position);text-decoration:none;white-space:pre">51,542,796</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:503.7pt;position:var(--position);text-decoration:none;white-space:pre"> available </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">for future grants.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock options granted under the 2018 Plan expire no later than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:373.76pt;position:var(--position);text-decoration:none;white-space:pre">ten years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:409.54pt;position:var(--position);text-decoration:none;white-space:pre"> from the date of grant. Stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">option exercise prices shall be equal to the fair market value of the underlying common stock on the date of grant. If, at the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">time we grant a stock option, the optionee directly or by attribution owns stock possessing more than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:464.21pt;position:var(--position);text-decoration:none;white-space:pre">10%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:482.54pt;position:var(--position);text-decoration:none;white-space:pre"> of the total </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">combined voting power of all classes of our stock, the stock option exercise price shall be at least </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:449.98pt;position:var(--position);text-decoration:none;white-space:pre">110%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:473.31pt;position:var(--position);text-decoration:none;white-space:pre"> of the fair market </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">value of the underlying common stock and shall not be exercisable more than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:370.65pt;position:var(--position);text-decoration:none;white-space:pre">five years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:409.76pt;position:var(--position);text-decoration:none;white-space:pre"> after the date of grant.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:187.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We grant service-based and performance-based stock options to employees under the 2018 Plan. Service-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">based stock options generally vest over a period of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:263.57pt;position:var(--position);text-decoration:none;white-space:pre">four years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:303.81pt;position:var(--position);text-decoration:none;white-space:pre"> from the date of the stock option grant. Performance-based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:211.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock options vest upon the achievement of specified milestones. Other stock awards (restricted stock awards and restricted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock units) have variable vesting schedules as determined by our board of directors on the date of grant.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:247.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Under certain circumstances, stock options may be exercised prior to vesting, subject to our right to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:259.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">repurchase the shares underlying such stock option at the exercise price paid per share. Our repurchase rights would </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:271.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">generally terminate on a vesting schedule identical to the vesting schedule of the exercised stock option. During </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:507.94pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:527.94pt;position:var(--position);text-decoration:none;white-space:pre"> and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:283.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">, we did not repurchase any shares under the 2018 Plan. As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:328.02pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:406.56pt;position:var(--position);text-decoration:none;white-space:pre">, we have no shares outstanding </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:295.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">subject to repurchase under the 2018 Plan.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:319.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:145.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:224.48000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, our Non‑Employee Director Compensation Policy adopted by our board of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:331.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">directors in March 2014, as amended, provides for the automatic grant to non‑employee directors of the following types of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:343.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">equity awards under the 2018 Plan:</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:367.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">First Director Option</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:181.07999999999998pt;position:var(--position);text-decoration:none;white-space:pre">. Each person who becomes a non‑employee director, whether by election by our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:379.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">stockholders or by appointment by our board of directors to fill a vacancy, will automatically be granted a stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:391.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">option to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:170.82pt;position:var(--position);text-decoration:none;white-space:pre">270,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:203.32pt;position:var(--position);text-decoration:none;white-space:pre"> shares of common stock, or First Director Option, on the date such person first </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:403.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">becomes a non‑employee director. The First Director Option vests annually over </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:419.21pt;position:var(--position);text-decoration:none;white-space:pre">three years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:462.75pt;position:var(--position);text-decoration:none;white-space:pre"> upon each </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:415.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">anniversary date of appointment to our board of directors.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:439.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76.5pt;position:var(--position);text-decoration:none;white-space:pre">•</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Subsequent Director Option</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:207.18pt;position:var(--position);text-decoration:none;white-space:pre">. Each non‑employee director (other than any director receiving a First Director </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:451.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Option on the date of the annual meeting) will automatically be granted a subsequent stock option to purchase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:463.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">180,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:127pt;position:var(--position);text-decoration:none;white-space:pre"> shares of common stock, a Subsequent Director Option, on the date of the annual meeting of stockholders </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:475.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">in each year during such director’s service on our board of directors. The Subsequent Director Option vests in full </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:487.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">on the earlier of: (i) the date of the next annual meeting of our stockholders or (ii) the first anniversary of the date </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:499.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">of grant.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:529.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2018 Inducement Award Plan</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:553.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">December 2018</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:195.87pt;position:var(--position);text-decoration:none;white-space:pre">, our board of directors approved the adoption of the 2018 Inducement Award Plan, or </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:565.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the Inducement Plan, pursuant to which we reserved </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:270.22pt;position:var(--position);text-decoration:none;white-space:pre">3,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:310.22pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock to be used exclusively for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:577.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">grants of inducement awards to individuals who were not previously Geron employees or non-employee directors, other </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:589.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">than following a bona fide period of non-employment. Since adoption of the Inducement Plan, the compensation </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:601.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">committee of our board of directors, or the compensation committee, has approved amendments to our Inducement Plan to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:613.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">increase the aggregate total number of shares issuable under such plan to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:352.03pt;position:var(--position);text-decoration:none;white-space:pre">51,300,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:397.03pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock. The </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:625.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">most recent amendment, approved by the compensation committee in August 2025, increased the total number of shares </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:637.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">issuable under such plan by </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:171.45999999999998pt;position:var(--position);text-decoration:none;white-space:pre">11,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:216.46pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:336.65pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:361.09pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:439.63pt;position:var(--position);text-decoration:none;white-space:pre">, an aggregate total of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:649.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">43,818,645</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> shares of common stock have been reserved under the Inducement Plan, wit</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:409.56pt;position:var(--position);text-decoration:none;white-space:pre">h </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:417.06pt;position:var(--position);text-decoration:none;white-space:pre">5,137,263</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:457.06pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:459.56pt;position:var(--position);text-decoration:none;white-space:pre">available for future </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:661.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">grants.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:685.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The Inducement Plan provides for the grant of nonstatutory stock options, stock appreciation rights, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:697.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">restricted stock awards, restricted stock units and other stock awards, and all awards under the Inducement Plan are </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:709.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">intended to mee</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.3pt;position:var(--position);text-decoration:none;white-space:pre">t the standards under Rule 5635(c)(4) of the Nasdaq Listing Rules. The terms and conditions of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:721.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Inducement Plan and the inducement awards to be granted thereunder are substantially similar to our stockholder-approved </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:733.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2018 Pl</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:89.33pt;position:var(--position);text-decoration:none;white-space:pre">an.</span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Directors’ Market Value Stock Purchase Plan</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">October 2018</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:187.01pt;position:var(--position);text-decoration:none;white-space:pre">, our board of directors adopted a Directors’ Market Value Stock Purchase Plan, or the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Directors Market Plan. A total of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:193.07pt;position:var(--position);text-decoration:none;white-space:pre">1,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:233.07pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock have been reserved for the Directors Market Plan. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Under the Directors Market Plan, non-employee directors may purchase shares of our common stock at the prevailing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:127.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">market price on the purchase date with cash compensation payable to them for their services as a board member. As stated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:139.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in Geron’s Non-Employee Director Compensation Policy, each non-employee director receives annual cash compensation, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:151.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">payable quarterly in arrears, for their services on the board and various committees of the board. As provided in the Non-</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:163.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Employee Director Compensation Policy, a non-employee director may elect to receive fully vested shares of common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:175.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock in lieu of cash and such shares shall be issuable from the Directors Market Plan.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:199.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock-Based Compensation</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:223.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table summarizes the stock‑based compensation expense included in research and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">development and selling, general and administrative expenses:</span></div><div style="position:var(--position);top:253.5pt;width:612pt"><div style="font-size:0pt;left:105.75pt;position:var(--position);width:400.5pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:192.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);width:201.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:201.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:56.03pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:192.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:192.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Research and development</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">8,388<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">9,595<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">7,765<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:192.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Selling, general and administrative</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">17,055<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">21,725<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">11,589<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:192.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total </span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">25,443<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">31,320<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">19,354<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:341pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock-based compensation of $</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:219.66pt;position:var(--position);text-decoration:none;white-space:pre">1.3</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:232.16pt;position:var(--position);text-decoration:none;white-space:pre"> million and $</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:287.94pt;position:var(--position);text-decoration:none;white-space:pre">0.7</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:300.44pt;position:var(--position);text-decoration:none;white-space:pre"> million was capitalized to inventory for the twelve months </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:353pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:84.86pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:163.4pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024, respectively, and was excluded from the table above. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:422pt;position:var(--position);text-decoration:none;white-space:pre">No</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.22pt;position:var(--position);text-decoration:none;white-space:pre"> stock-based compensation </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:365pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">was capitalized to inventory for the twelve months ended December 31, 2023. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:373.15pt;position:var(--position);text-decoration:none;white-space:pre">Stock-based compensation of approximately </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:377pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">$0.3</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76pt;position:var(--position);text-decoration:none;white-space:pre"> million and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:126.78pt;position:var(--position);text-decoration:none;white-space:pre">$0.1</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:144.28pt;position:var(--position);text-decoration:none;white-space:pre"> million was included in cost of goods sold for the twelve months ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.58pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:513.12pt;position:var(--position);text-decoration:none;white-space:pre"> and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:389pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2024, respectively.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:413pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table summarizes share-based compensation expense associated with each of our stock-based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:425pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">compensation programs:</span></div><div style="position:var(--position);top:449pt;width:612pt"><div style="font-size:0pt;left:109.5pt;position:var(--position);width:393pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:197.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:63pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:54.75pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);width:192.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:192.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:51.53pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:197.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:12.75pt;width:69pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:26.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:12.75pt;width:63pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:23.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:12.75pt;width:54.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:19.37pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Service based options</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:25.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">24,733<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:25.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:23.79pt"></span></span><span style="left:31.419999999999998pt;position:var(--position)">24,863<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:25.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.54pt"></span></span><span style="left:23.169999999999998pt;position:var(--position)">15,722<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Performance based options</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:40.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.29pt"></span></span><span style="left:54.92pt;position:var(--position)">29<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:40.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.79pt"></span></span><span style="left:36.42pt;position:var(--position)">6,538<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:40.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:28.169999999999998pt;position:var(--position)">3,167<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Restricted stock units</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:55.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:39.79pt"></span></span><span style="left:42.42pt;position:var(--position)">1,266<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:55.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:41.29pt"></span></span><span style="left:48.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:55.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:33.04pt"></span></span><span style="left:40.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Employee stock purchase plan</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:70.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.29pt"></span></span><span style="left:49.92pt;position:var(--position)">719<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:70.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:36.29pt"></span></span><span style="left:43.92pt;position:var(--position)">661<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:70.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.04pt"></span></span><span style="left:35.67pt;position:var(--position)">465<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total </span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:85.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">26,747<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="height:15pt;left:269.25pt;overflow:hidden;position:var(--position);top:85.5pt;width:3pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:3pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$</span><span style="left:7.63pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:85.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:23.79pt"></span></span><span style="left:31.419999999999998pt;position:var(--position)">32,062<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:85.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.54pt"></span></span><span style="left:23.169999999999998pt;position:var(--position)">19,354<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:566.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">The table above was not adjusted for stock-based compensation amounts capitalized to inventory </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:484.87pt;position:var(--position);text-decoration:none;white-space:pre">for the twelve </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:578.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">months ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:116.78999999999999pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:195.33pt;position:var(--position);text-decoration:none;white-space:pre"> and 2024.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:602.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:118.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:197.48000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, total compensation cost related to unvested share‑based payment awards not yet </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:614.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">recognized, net of estimated forfeitures, and assuming no probability of achievement for outstanding performance-based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:626.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock options, was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:134.56pt;position:var(--position);text-decoration:none;white-space:pre">$40.7 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:188.41pt;position:var(--position);text-decoration:none;white-space:pre">, which is expected to be recognized over the next </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:390.66pt;position:var(--position);text-decoration:none;white-space:pre">37 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:432.59pt;position:var(--position);text-decoration:none;white-space:pre"> on a weighted‑average basis.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:650.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:152.32999999999998pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:157.32999999999998pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:177.32999999999998pt;position:var(--position);text-decoration:none;white-space:pre">, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:199.26pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:219.26pt;position:var(--position);text-decoration:none;white-space:pre">, we recorded stock‑based compensation expense of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:429.11pt;position:var(--position);text-decoration:none;white-space:pre">$0.1</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:446.61pt;position:var(--position);text-decoration:none;white-space:pre"> million, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:482.96pt;position:var(--position);text-decoration:none;white-space:pre">$0.1</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:500.46pt;position:var(--position);text-decoration:none;white-space:pre"> million and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:662.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">$0.7</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:76pt;position:var(--position);text-decoration:none;white-space:pre"> million for stock options held by consultants, respectively. This stock‑based compensation expense is included in the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:674.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">tables above.</span></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock Options </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents stock option activity for the year ended December 31, 2025:</span></div><div style="position:var(--position);top:115.5pt;width:612pt"><div style="font-size:0pt;left:93.37pt;position:var(--position);width:425.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:122.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:12pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="7" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);width:297pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:297pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:102.09pt;position:var(--position);text-decoration:none;white-space:pre">Outstanding Stock Options</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:12pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:3.23pt;position:var(--position);text-decoration:none;white-space:pre">Weighted Average</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:12pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.33pt;position:var(--position);text-decoration:none;white-space:pre">Aggregate</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:16.34pt;position:var(--position);text-decoration:none;white-space:pre">Number of</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.75pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:3.23pt;position:var(--position);text-decoration:none;white-space:pre">Weighted Average</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:16.22pt;position:var(--position);text-decoration:none;white-space:pre">Remaining</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:20.22pt;position:var(--position);text-decoration:none;white-space:pre">Intrinsic</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:23.33pt;position:var(--position);text-decoration:none;white-space:pre">Shares</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.75pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:10.57pt;position:var(--position);text-decoration:none;white-space:pre">Exercise Price</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.35pt;position:var(--position);text-decoration:none;white-space:pre">Contractual Life</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.88pt;position:var(--position);text-decoration:none;white-space:pre">Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:10.12pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.89pt;position:var(--position);text-decoration:none;white-space:pre">Per Share</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:18.33pt;position:var(--position);text-decoration:none;white-space:pre">(In years)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:10.12pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60.75pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance at December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:60.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">75,967</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:60.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.39<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:73.5pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Granted</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">35,540</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">1.74<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:86.25pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Exercised</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:86.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:43.8pt;position:var(--position);text-decoration:none;white-space:pre">(1,275)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:86.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">1.19<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:99pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Forfeited or expired</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:99pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:39.8pt;position:var(--position);text-decoration:none;white-space:pre">(27,862)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:99pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.62<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:111.75pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance at December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">82,370</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.06<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:53.12pt;position:var(--position);text-decoration:none;white-space:pre">5.86</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:41.71pt"></span></span><span style="left:48.34pt;position:var(--position)">2,613<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:124.5pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Exercisable at December 31, 2025</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">45,954</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.18<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:53.12pt;position:var(--position);text-decoration:none;white-space:pre">3.54</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:41.71pt"></span></span><span style="left:48.34pt;position:var(--position)">1,788<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:23.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:137.25pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.89pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Fully vested and expected to vest at </span></div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">78,935</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.07<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:53.12pt;position:var(--position);text-decoration:none;white-space:pre">5.72</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:41.71pt"></span></span><span style="left:48.34pt;position:var(--position)">2,525<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:287pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The weighted-average estimated fair value of stock options granted during the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:486.33pt;position:var(--position);text-decoration:none;white-space:pre">December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:299pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:83.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.93pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:142.93pt;position:var(--position);text-decoration:none;white-space:pre"> was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:163.47pt;position:var(--position);text-decoration:none;white-space:pre">$1.17</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:185.97pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:190.97pt;position:var(--position);text-decoration:none;white-space:pre">$2.05</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:213.47pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:232.9pt;position:var(--position);text-decoration:none;white-space:pre">$1.95</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:255.4pt;position:var(--position);text-decoration:none;white-space:pre"> per share, respectively. The total pretax intrinsic value of stock options </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:311pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exercised during </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:127.31pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:147.31pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:152.31pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:172.31pt;position:var(--position);text-decoration:none;white-space:pre">, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:194.24pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:214.24pt;position:var(--position);text-decoration:none;white-space:pre"> was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:234.78pt;position:var(--position);text-decoration:none;white-space:pre">$0.5 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:283.63pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:286.13pt;position:var(--position);text-decoration:none;white-space:pre">$41.2 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:339.98pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:359.41pt;position:var(--position);text-decoration:none;white-space:pre">$12.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:413.26pt;position:var(--position);text-decoration:none;white-space:pre">, respectively. The intrinsic value </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:323pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">was calculated as the difference between the fair value of the Company's common stock and the exercise price of the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:335pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">option. Cash received from the exercise of stock options in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:296.3pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:316.3pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:321.3pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:341.3pt;position:var(--position);text-decoration:none;white-space:pre">, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:363.23pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:383.23pt;position:var(--position);text-decoration:none;white-space:pre"> totaled approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:475.6pt;position:var(--position);text-decoration:none;white-space:pre">$1.5 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:524.45pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:529.45pt;position:var(--position);text-decoration:none;white-space:pre">$31.6 </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:347pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:87.35pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:89.85pt;position:var(--position);text-decoration:none;white-space:pre">and</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:104.28pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:106.78pt;position:var(--position);text-decoration:none;white-space:pre">$12.4 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:160.63pt;position:var(--position);text-decoration:none;white-space:pre">, respectively. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:218.88pt;position:var(--position);text-decoration:none;white-space:pre">The total grant date fair value of options vested during </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:439.18pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:459.18pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:464.18pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:484.18pt;position:var(--position);text-decoration:none;white-space:pre">, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:506.11pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:526.11pt;position:var(--position);text-decoration:none;white-space:pre"> was </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:359pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">$41.5</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:81pt;position:var(--position);text-decoration:none;white-space:pre"> million, $</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.35pt;position:var(--position);text-decoration:none;white-space:pre">60.6</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:139.85pt;position:var(--position);text-decoration:none;white-space:pre"> million, and $</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:198.13pt;position:var(--position);text-decoration:none;white-space:pre">40.6</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:215.63pt;position:var(--position);text-decoration:none;white-space:pre"> million, respectively.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:389pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The fair value of stock options granted has been estimated using the following assumptions:</span></div><div style="position:var(--position);top:413pt;width:612pt"><div style="font-size:0pt;left:91.12pt;position:var(--position);width:429.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:180pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);width:246.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:246.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:78.53pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Dividend yield</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected volatility range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">72%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">74%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">72%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">87%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">82%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">83%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Risk-free interest rate range</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">3.7%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">4.5%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">3.5%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">4.6%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:11.13pt;position:var(--position);text-decoration:none;white-space:pre">3.42%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.870000000000005pt;position:var(--position);text-decoration:none;white-space:pre">4.94%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected term range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:27.88pt;position:var(--position);text-decoration:none;white-space:pre">6.0</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:39.129999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> yrs</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:27.88pt;position:var(--position);text-decoration:none;white-space:pre">6.0</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:39.129999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> yrs</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:27.88pt;position:var(--position);text-decoration:none;white-space:pre">6.0</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:39.129999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> yrs</span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:515.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:152.32999999999998pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:157.32999999999998pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:177.32999999999998pt;position:var(--position);text-decoration:none;white-space:pre">, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:199.26pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:219.26pt;position:var(--position);text-decoration:none;white-space:pre">, our board of directors awarded </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:349.97pt;position:var(--position);text-decoration:none;white-space:pre">67,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:377.47pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:382.47pt;position:var(--position);text-decoration:none;white-space:pre">208,100</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.97pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:434.4pt;position:var(--position);text-decoration:none;white-space:pre">832,790</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:466.9pt;position:var(--position);text-decoration:none;white-space:pre"> performance-based </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:527.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock options, respectively, to certain employees. These performance-based stock options are included in the outstanding </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:539.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">stock options table above. Performance-based stock options vest only upon achievement of discrete milestones. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:557.5pt;width:612pt"><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">Restricted Stock Units</span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:581.5pt;width:612pt"><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">We grant service-based restricted stock units ("</span></span><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:310.33000000000004pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">RSU</span></span><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:329.77pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">s") under our equity plans to employees. The service-</span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:593.5pt;width:612pt"><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">based vesting period for an employee RSU is generally </span></span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:281.32pt;position:var(--position);text-decoration:none;white-space:pre">four years</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:321.56pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:324.06pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">from the date of the grant. </span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:623.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table summarizes the activity for RSUs:</span></div><div style="position:var(--position);top:635.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:299.25pt"></td><td style="padding:0;width:85.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:107.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:107.25pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:21.98pt;position:var(--position);white-space:pre">Weighted Average</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:12.75pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:85.5pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:31.2pt;position:var(--position);white-space:pre">Shares</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:12.75pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:107.25pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.88pt;position:var(--position);white-space:pre">Grant Date Fair Value</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Unvested at December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:25.5pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:71.46pt"></span></span><span style="left:74.08999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:25.5pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:93.21pt"></span></span><span style="left:95.83999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Granted</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:38.25pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:50.87pt;position:var(--position);text-decoration:none;white-space:pre">5,336,250</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:38.25pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:90.62pt;position:var(--position);text-decoration:none;white-space:pre">2.22</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Vested</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:51pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:71.46pt"></span></span><span style="left:74.08999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:51pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:93.21pt"></span></span><span style="left:95.83999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:63.75pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Forfeited</span></div></div></div></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:63.75pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.55pt;position:var(--position);text-decoration:none;white-space:pre">(2,186,500)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:63.75pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:87.21pt"></span></span><span style="left:89.83999999999999pt;position:var(--position)">2.42<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:76.5pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Unvested at December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:76.5pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:50.87pt;position:var(--position);text-decoration:none;white-space:pre">3,149,750</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:76.5pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:87.21pt"></span></span><span style="left:89.83999999999999pt;position:var(--position)">2.08<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">Restricted Stock Awards</span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:202.53pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:281.07pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:286.07pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:306.07pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:325.5pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:345.5pt;position:var(--position);text-decoration:none;white-space:pre">, we issued </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:392.13pt;position:var(--position);text-decoration:none;white-space:pre">22,073</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:419.63pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:424.63pt;position:var(--position);text-decoration:none;white-space:pre">8,351</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:447.13pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:466.56pt;position:var(--position);text-decoration:none;white-space:pre">36,864</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:494.06pt;position:var(--position);text-decoration:none;white-space:pre"> shares of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:97.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">common stock, respectively, under the Directors Market Plan. The weighted average grant date fair value of stock granted </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:109.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">during the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:151.74pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:230.28pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:232.78pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:252.78pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:272.21000000000004pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:292.21000000000004pt;position:var(--position);text-decoration:none;white-space:pre"> was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:312.75pt;position:var(--position);text-decoration:none;white-space:pre">$1.42</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:335.25pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:340.25pt;position:var(--position);text-decoration:none;white-space:pre">$3.84</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:362.75pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:382.18pt;position:var(--position);text-decoration:none;white-space:pre">$2.37</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:404.68pt;position:var(--position);text-decoration:none;white-space:pre"> per share, respectively. The total </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:121.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">fair value of vested stock grants during </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:216.95pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:236.95pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:241.95pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:261.95pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:281.38pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:301.38pt;position:var(--position);text-decoration:none;white-space:pre"> was less than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:359.1pt;position:var(--position);text-decoration:none;white-space:pre">$0.1</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:376.6pt;position:var(--position);text-decoration:none;white-space:pre"> million, less than </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:450.13pt;position:var(--position);text-decoration:none;white-space:pre">$0.1</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:467.63pt;position:var(--position);text-decoration:none;white-space:pre"> million and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:518.4100000000001pt;position:var(--position);text-decoration:none;white-space:pre">$0.1</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:535.9100000000001pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:133.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">million, respectively.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:157.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Employee Stock Purchase Plan</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:181.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In March 2014, our board of directors adopted the 2014 Employee Stock Purchase Plan, or 2014 Purchase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:193.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Plan. The 2014 Purchase Plan was approved by our stockholders in May 2014. The 2014 Purchase Plan replaced the 1996 </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:205.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Employee Stock Purchase Plan, or 1996 Purchase Plan, which was terminated effective as of the date the 2014 Purchase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:217.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Plan was approved by our stockholders. In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:231.16pt;position:var(--position);text-decoration:none;white-space:pre">May 2022</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:271.98pt;position:var(--position);text-decoration:none;white-space:pre">, our stockholders approved an amendment to our 2014 Purchase Plan </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:229.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to increase the total number of shares issuable under such plan by </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:323.21pt;position:var(--position);text-decoration:none;white-space:pre">1,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:363.21pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock, for an aggregate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:241.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">total reserve of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:120.91pt;position:var(--position);text-decoration:none;white-space:pre">2,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:160.91pt;position:var(--position);text-decoration:none;white-space:pre"> shares. In the May 2025 annual meeting, stockholders approved an amendment to increase the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:253.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reserve for the 2014 Purchase Plan by </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:212.53pt;position:var(--position);text-decoration:none;white-space:pre">6,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:252.53pt;position:var(--position);text-decoration:none;white-space:pre"> shares, for an aggregate total reserve of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:414.82pt;position:var(--position);text-decoration:none;white-space:pre">8,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:454.82pt;position:var(--position);text-decoration:none;white-space:pre"> shares. At</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:497.28pt;position:var(--position);text-decoration:none;white-space:pre"> </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:265.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:137.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:142.04000000000002pt;position:var(--position);text-decoration:none;white-space:pre">an aggregate of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:206.12pt;position:var(--position);text-decoration:none;white-space:pre">2,380,619</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:246.12pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock have been issued under the 2014 Employee </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:277.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Stock Purchase Plan since its adoption.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:301.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The 2014 Purchase Plan is comprised of a series of offering periods, each with a maximum duration (not to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:313.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">exceed </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:88.72pt;position:var(--position);text-decoration:none;white-space:pre">12 months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:130.65pt;position:var(--position);text-decoration:none;white-space:pre">) with new offering periods commencing on January 1st and July 1st of each year. The date an employee </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:325.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">enters the offering period will be designated as the entry date for purposes of that offering period. An employee may </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:337.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">participate only in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:133.67000000000002pt;position:var(--position);text-decoration:none;white-space:pre">one</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:148.1pt;position:var(--position);text-decoration:none;white-space:pre"> offering period at a time. Each offering period consists of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:382.84pt;position:var(--position);text-decoration:none;white-space:pre">two</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:397.83pt;position:var(--position);text-decoration:none;white-space:pre"> consecutive purchase periods of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:530.74pt;position:var(--position);text-decoration:none;white-space:pre">six </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:349.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">months</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:87.93pt;position:var(--position);text-decoration:none;white-space:pre">’ duration, with the last day of such period designated a purchase date.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:373.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Under the terms of the 2014 Purchase Plan, employees can choose to have up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:443.96pt;position:var(--position);text-decoration:none;white-space:pre">10%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:462.29pt;position:var(--position);text-decoration:none;white-space:pre"> of their annual salary </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:385.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">withheld to purchase our common stock, up to a limit of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:285.51pt;position:var(--position);text-decoration:none;white-space:pre">$25,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:318.01pt;position:var(--position);text-decoration:none;white-space:pre"> per year. An employee may not make additional </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:397.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">payments into such account or increase the withholding percentage during the offering period.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:421.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The purchase price per share at which common stock is purchased by the employee on each purchase date </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:433.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">within the offering period is equal to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:207.51pt;position:var(--position);text-decoration:none;white-space:pre">85%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:225.84pt;position:var(--position);text-decoration:none;white-space:pre"> of the lower of (i) the fair market value per share of our common stock on the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:445.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">employee’s entry date into that offering period or (ii) the fair market value per share of our common stock on the purchase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:457.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">date. If the fair market value per share of our common stock on the purchase date is less than the fair market value at the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:469.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">beginning of the offering period, a new </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:217.8pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:227.8pt;position:var(--position);text-decoration:none;white-space:pre"> month offering period will automatically begin on the first business day </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:481.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">following the purchase date with a new fair market value.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:511.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The fair value of employee stock purchases has been estimated using the Black-Scholes option‑pricing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">model with the following assumptions:</span></div><div style="position:var(--position);top:541.5pt;width:612pt"><div style="font-size:0pt;left:91.12pt;position:var(--position);width:429.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:180pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);width:246.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:246.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:78.53pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Dividend yield</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected volatility range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:16.76pt;position:var(--position);text-decoration:none;white-space:pre">69%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:33.25pt;position:var(--position);text-decoration:none;white-space:pre">. to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:47pt;position:var(--position);text-decoration:none;white-space:pre">89%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">72%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:43.62pt;position:var(--position);text-decoration:none;white-space:pre">119%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">79%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">83%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Risk-free interest rate range</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">4.0%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">4.3%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">4.8%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">5.4%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:13.38pt;position:var(--position);text-decoration:none;white-space:pre">4.73%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:36.62pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:48.120000000000005pt;position:var(--position);text-decoration:none;white-space:pre">5.4%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected term range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:21pt;position:var(--position);text-decoration:none;white-space:pre">6</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:25.5pt;position:var(--position);text-decoration:none;white-space:pre"> - </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.99pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:41.989999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> mos</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:21pt;position:var(--position);text-decoration:none;white-space:pre">6</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:25.5pt;position:var(--position);text-decoration:none;white-space:pre"> - </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.99pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:41.989999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> mos</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:21pt;position:var(--position);text-decoration:none;white-space:pre">6</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:25.5pt;position:var(--position);text-decoration:none;white-space:pre"> - </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.99pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:41.989999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> mos</span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:644pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The weighted average estimated fair value of employees’ purchase rights for the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:494.9pt;position:var(--position);text-decoration:none;white-space:pre">December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:656pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:83.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.93pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:142.93pt;position:var(--position);text-decoration:none;white-space:pre"> was </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:163.47pt;position:var(--position);text-decoration:none;white-space:pre">$1.05</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:185.97pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:190.97pt;position:var(--position);text-decoration:none;white-space:pre">$0.82</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:213.47pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:232.9pt;position:var(--position);text-decoration:none;white-space:pre">$1.10</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:255.4pt;position:var(--position);text-decoration:none;white-space:pre"> per share, respectively. </span></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Common Stock Reserved for Future Issuance</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Common stock reserved for future issuance as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:319.64pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:398.18pt;position:var(--position);text-decoration:none;white-space:pre"> is as follows:</span></div><div style="position:var(--position);top:109.5pt;width:612pt"><div style="font-size:0pt;left:157.87pt;position:var(--position);width:296.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:209.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:81pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Outstanding stock options and unvested RSUs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:33.37pt;position:var(--position);text-decoration:none;white-space:pre">86,110,557</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2011 Plan, 2018 Plan and Inducement Plan</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:15pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:33.37pt;position:var(--position);text-decoration:none;white-space:pre">57,528,890</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Employee stock purchase plan</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:30pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:38.37pt;position:var(--position);text-decoration:none;white-space:pre">5,619,381</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Warrants outstanding</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:45pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:29.29pt"></span></span><span style="left:31.919999999999998pt;position:var(--position)">29,293,291<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:60pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:28.37pt;position:var(--position);text-decoration:none;white-space:pre">178,552,119</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 675000000 1350000000 68007741 2.45 2.449 213300000 41999998 8002668 3.00 2.99 141000000.0 5400000 2600000 29053145 59433145 0.001 1162376 1.30 1.30 1500000 240146 1071981 1.30 1.30 1400000 1402522 100000000 0.030 0 P10Y P4Y 10000000 20000000 43360000 98971971 51542796 P10Y 0.10 1.10 P5Y P4Y 270000 P3Y 180000 3000000 51300000 11000000 43818645 5137263 1000000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table summarizes the stock‑based compensation expense included in research and </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:235.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">development and selling, general and administrative expenses:</span></div><div style="position:var(--position);top:253.5pt;width:612pt"><div style="font-size:0pt;left:105.75pt;position:var(--position);width:400.5pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:192.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:65.25pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);width:201.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:201.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:56.03pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:192.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:12.75pt;width:65.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.62pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:192.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Research and development</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">8,388<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">9,595<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:25.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:38.67pt;position:var(--position)">7,765<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:192.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Selling, general and administrative</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">17,055<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">21,725<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:40.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:31.04pt"></span></span><span style="left:33.67pt;position:var(--position)">11,589<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:192.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:192.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total </span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:195.75pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">25,443<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:264pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">31,320<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:332.25pt;position:var(--position);top:55.5pt;width:65.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:65.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:26.04pt"></span></span><span style="left:33.67pt;position:var(--position)">19,354<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table summarizes share-based compensation expense associated with each of our stock-based </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:425pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">compensation programs:</span></div><div style="position:var(--position);top:449pt;width:612pt"><div style="font-size:0pt;left:109.5pt;position:var(--position);width:393pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:197.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:63pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:54.75pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);width:192.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:192.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:51.53pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:197.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:12.75pt;width:69pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:26.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:12.75pt;width:63pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:23.5pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:12.75pt;width:54.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:19.37pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Service based options</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:25.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">24,733<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:25.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:23.79pt"></span></span><span style="left:31.419999999999998pt;position:var(--position)">24,863<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:25.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.54pt"></span></span><span style="left:23.169999999999998pt;position:var(--position)">15,722<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Performance based options</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:40.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.29pt"></span></span><span style="left:54.92pt;position:var(--position)">29<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:40.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:33.79pt"></span></span><span style="left:36.42pt;position:var(--position)">6,538<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:40.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:28.169999999999998pt;position:var(--position)">3,167<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Restricted stock units</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:55.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:39.79pt"></span></span><span style="left:42.42pt;position:var(--position)">1,266<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:55.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:41.29pt"></span></span><span style="left:48.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:55.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:33.04pt"></span></span><span style="left:40.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Employee stock purchase plan</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:70.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.29pt"></span></span><span style="left:49.92pt;position:var(--position)">719<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:70.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:36.29pt"></span></span><span style="left:43.92pt;position:var(--position)">661<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:70.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:28.04pt"></span></span><span style="left:35.67pt;position:var(--position)">465<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:197.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:197.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total </span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:200.25pt;position:var(--position);top:85.5pt;width:69pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:29.79pt"></span></span><span style="left:37.42pt;position:var(--position)">26,747<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="height:15pt;left:269.25pt;overflow:hidden;position:var(--position);top:85.5pt;width:3pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:3pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$</span><span style="left:7.63pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:272.25pt;position:var(--position);top:85.5pt;width:63pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:63pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:23.79pt"></span></span><span style="left:31.419999999999998pt;position:var(--position)">32,062<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:338.25pt;position:var(--position);top:85.5pt;width:54.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:54.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:15.54pt"></span></span><span style="left:23.169999999999998pt;position:var(--position)">19,354<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 8388000 9595000 7765000 17055000 21725000 11589000 25443000 31320000 19354000 1300000 700000 0 300000 100000 24733000 24863000 15722000 29000 6538000 3167000 1266000 0 0 719000 661000 465000 26747000 32062000 19354000 40700000 P37M 100000 100000 700000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table presents stock option activity for the year ended December 31, 2025:</span><div style="position:var(--position);top:115.5pt;width:612pt"><div style="font-size:0pt;left:93.37pt;position:var(--position);width:425.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:122.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:12pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="7" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);width:297pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:297pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:102.09pt;position:var(--position);text-decoration:none;white-space:pre">Outstanding Stock Options</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:12pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:3.23pt;position:var(--position);text-decoration:none;white-space:pre">Weighted Average</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:12pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.33pt;position:var(--position);text-decoration:none;white-space:pre">Aggregate</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:16.34pt;position:var(--position);text-decoration:none;white-space:pre">Number of</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.75pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:3.23pt;position:var(--position);text-decoration:none;white-space:pre">Weighted Average</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:16.22pt;position:var(--position);text-decoration:none;white-space:pre">Remaining</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:24pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:20.22pt;position:var(--position);text-decoration:none;white-space:pre">Intrinsic</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:23.33pt;position:var(--position);text-decoration:none;white-space:pre">Shares</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.75pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:10.57pt;position:var(--position);text-decoration:none;white-space:pre">Exercise Price</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:6.35pt;position:var(--position);text-decoration:none;white-space:pre">Contractual Life</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:36pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.56pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:24.88pt;position:var(--position);text-decoration:none;white-space:pre">Value</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:10.12pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:17.89pt;position:var(--position);text-decoration:none;white-space:pre">Per Share</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:18.33pt;position:var(--position);text-decoration:none;white-space:pre">(In years)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:48pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:10.12pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60.75pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance at December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:60.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">75,967</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:60.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.39<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:73.5pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Granted</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">35,540</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">1.74<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:86.25pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Exercised</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:86.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:43.8pt;position:var(--position);text-decoration:none;white-space:pre">(1,275)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:86.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">1.19<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:99pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Forfeited or expired</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:99pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:39.8pt;position:var(--position);text-decoration:none;white-space:pre">(27,862)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:99pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.62<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:111.75pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance at December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">82,370</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.06<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:53.12pt;position:var(--position);text-decoration:none;white-space:pre">5.86</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:111.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:41.71pt"></span></span><span style="left:48.34pt;position:var(--position)">2,613<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:124.5pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Exercisable at December 31, 2025</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">45,954</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.18<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:53.12pt;position:var(--position);text-decoration:none;white-space:pre">3.54</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:124.5pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:41.71pt"></span></span><span style="left:48.34pt;position:var(--position)">1,788<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:23.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:137.25pt;width:122.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.89pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Fully vested and expected to vest at </span></div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:122.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:3pt double #000;font-size:0;text-align:left;vertical-align:top"><div style="left:125.25pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.12pt;position:var(--position);text-decoration:none;white-space:pre">78,935</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:207pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:45.71pt"></span></span><span style="left:52.34pt;position:var(--position)">2.07<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:279.75pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:53.12pt;position:var(--position);text-decoration:none;white-space:pre">5.72</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:352.5pt;position:var(--position);top:137.25pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:14.49pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:5.54pt;width:41.71pt"></span></span><span style="left:48.34pt;position:var(--position)">2,525<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 75967000 2.39 35540000 1.74 1275000 1.19 27862000 2.62 82370000 2.06 P5Y10M9D 2613000 45954000 2.18 P3Y6M14D 1788000 78935000 2.07 P5Y8M19D 2525000 1.17 2.05 1.95 500000 41200000 12000000.0 1500000 31600000 12400000 41500000 60600000 40600000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The fair value of stock options granted has been estimated using the following assumptions:</span><div style="position:var(--position);top:413pt;width:612pt"><div style="font-size:0pt;left:91.12pt;position:var(--position);width:429.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:180pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);width:246.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:246.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:78.53pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Dividend yield</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected volatility range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">72%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">74%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">72%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">87%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">82%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">83%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Risk-free interest rate range</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">3.7%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">4.5%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">3.5%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">4.6%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:11.13pt;position:var(--position);text-decoration:none;white-space:pre">3.42%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.870000000000005pt;position:var(--position);text-decoration:none;white-space:pre">4.94%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected term range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:27.88pt;position:var(--position);text-decoration:none;white-space:pre">6.0</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:39.129999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> yrs</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:27.88pt;position:var(--position);text-decoration:none;white-space:pre">6.0</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:39.129999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> yrs</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:27.88pt;position:var(--position);text-decoration:none;white-space:pre">6.0</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:39.129999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> yrs</span></div></div></div></td></tr></tbody></table></div></div></div> 0 0 0 0.72 0.74 0.72 0.87 0.82 0.83 0.037 0.045 0.035 0.046 0.0342 0.0494 P6Y P6Y P6Y 67000 208100 832790 P4Y <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table summarizes the activity for RSUs:</span><div style="position:var(--position);top:635.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:299.25pt"></td><td style="padding:0;width:85.5pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:107.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:107.25pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:21.98pt;position:var(--position);white-space:pre">Weighted Average</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:12.75pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:85.5pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:31.2pt;position:var(--position);white-space:pre">Shares</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:12.75pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:107.25pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:14.88pt;position:var(--position);white-space:pre">Grant Date Fair Value</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Unvested at December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:25.5pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:71.46pt"></span></span><span style="left:74.08999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:25.5pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:93.21pt"></span></span><span style="left:95.83999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:38.25pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Granted</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:38.25pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:50.87pt;position:var(--position);text-decoration:none;white-space:pre">5,336,250</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:38.25pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:90.62pt;position:var(--position);text-decoration:none;white-space:pre">2.22</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:51pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Vested</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:51pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:71.46pt"></span></span><span style="left:74.08999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:51pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:93.21pt"></span></span><span style="left:95.83999999999999pt;position:var(--position)">—<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:63.75pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Forfeited</span></div></div></div></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:63.75pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:45.55pt;position:var(--position);text-decoration:none;white-space:pre">(2,186,500)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:63.75pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:87.21pt"></span></span><span style="left:89.83999999999999pt;position:var(--position)">2.42<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr><tr style="height:12.75pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:76.5pt;width:299.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:299.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Unvested at December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:299.25pt;position:var(--position);top:76.5pt;width:85.5pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:85.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;left:50.87pt;position:var(--position);text-decoration:none;white-space:pre">3,149,750</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:387.75pt;position:var(--position);top:76.5pt;width:107.25pt"><div><div style="line-height:8pt;position:var(--position);top:3.99pt;width:107.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:5.54pt;width:87.21pt"></span></span><span style="left:89.83999999999999pt;position:var(--position)">2.08<span style="display:inline-block;height:5.54pt;width:2.66pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 0 0 5336250 2.22 0 0 2186500 2.42 3149750 2.08 22073 8351 36864 1.42 3.84 2.37 100000 100000 100000 1000000 2000000 6000000 8000000 2380619 P12M 1 2 P6M 0.10 25000 0.85 P12M <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The fair value of employee stock purchases has been estimated using the Black-Scholes option‑pricing </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:523.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">model with the following assumptions:</span></div><div style="position:var(--position);top:541.5pt;width:612pt"><div style="font-size:0pt;left:91.12pt;position:var(--position);width:429.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:180pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);width:246.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:246.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:78.53pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Dividend yield</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:25.5pt;width:80.25pt"><div><div style="line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:35.07pt;position:var(--position);text-decoration:none;white-space:pre">0%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected volatility range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:16.76pt;position:var(--position);text-decoration:none;white-space:pre">69%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:33.25pt;position:var(--position);text-decoration:none;white-space:pre">. to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:47pt;position:var(--position);text-decoration:none;white-space:pre">89%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">72%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:43.62pt;position:var(--position);text-decoration:none;white-space:pre">119%</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:17.88pt;position:var(--position);text-decoration:none;white-space:pre">79%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">83%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Risk-free interest rate range</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">4.0%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">4.3%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:15.63pt;position:var(--position);text-decoration:none;white-space:pre">4.8%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:34.37pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:45.87pt;position:var(--position);text-decoration:none;white-space:pre">5.4%</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:13.38pt;position:var(--position);text-decoration:none;white-space:pre">4.73%</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:36.62pt;position:var(--position);text-decoration:none;white-space:pre"> to </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:48.120000000000005pt;position:var(--position);text-decoration:none;white-space:pre">5.4%</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:180pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:180pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expected term range</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:183pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:21pt;position:var(--position);text-decoration:none;white-space:pre">6</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:25.5pt;position:var(--position);text-decoration:none;white-space:pre"> - </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.99pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:41.989999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> mos</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:266.25pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:21pt;position:var(--position);text-decoration:none;white-space:pre">6</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:25.5pt;position:var(--position);text-decoration:none;white-space:pre"> - </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.99pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:41.989999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> mos</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="font-size:12pt;line-height:9pt;position:var(--position);top:5.32pt;width:80.25pt"><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:21pt;position:var(--position);text-decoration:none;white-space:pre">6</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:25.5pt;position:var(--position);text-decoration:none;white-space:pre"> - </span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:32.99pt;position:var(--position);text-decoration:none;white-space:pre">12</span><span style="font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:41.989999999999995pt;position:var(--position);text-decoration:none;white-space:pre"> mos</span></div></div></div></td></tr></tbody></table></div></div></div> 0 0 0 0.69 0.89 0.72 1.19 0.79 0.83 0.040 0.043 0.048 0.054 0.0473 0.054 P6M P12M P6M P12M P6M P12M 1.05 0.82 1.10 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Common stock reserved for future issuance as of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:319.64pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:398.18pt;position:var(--position);text-decoration:none;white-space:pre"> is as follows:</span><div style="position:var(--position);top:109.5pt;width:612pt"><div style="font-size:0pt;left:157.87pt;position:var(--position);width:296.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:209.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:81pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Outstanding stock options and unvested RSUs</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:33.37pt;position:var(--position);text-decoration:none;white-space:pre">86,110,557</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">2011 Plan, 2018 Plan and Inducement Plan</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:15pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:33.37pt;position:var(--position);text-decoration:none;white-space:pre">57,528,890</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Employee stock purchase plan</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:30pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:38.37pt;position:var(--position);text-decoration:none;white-space:pre">5,619,381</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Warrants outstanding</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:45pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:29.29pt"></span></span><span style="left:31.919999999999998pt;position:var(--position)">29,293,291<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:60pt;width:209.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:209.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:20.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:212.25pt;position:var(--position);top:60pt;width:81pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:81pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:28.37pt;position:var(--position);text-decoration:none;white-space:pre">178,552,119</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 86110557 57528890 5619381 29293291 178552119 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">NET LOSS PER COMMON SHARE</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:111pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Basic net income (loss) per share is calculated by dividing net income (loss) by the weighted-average </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:123pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">number of shares of common stock outstanding for the periods presented without consideration of potential common </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:135pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">shares. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:147pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Since we incurred a net loss for </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:249.97pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:269.97pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:274.97pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:294.97pt;position:var(--position);text-decoration:none;white-space:pre">, and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:316.9pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:336.9pt;position:var(--position);text-decoration:none;white-space:pre">, the diluted net loss per share calculation excludes </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:159pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">potential dilutive securities of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:179.99pt;position:var(--position);text-decoration:none;white-space:pre">86,350,703</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:224.99pt;position:var(--position);text-decoration:none;white-space:pre">, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:229.99pt;position:var(--position);text-decoration:none;white-space:pre">77,369,889</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:274.99pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:294.41999999999996pt;position:var(--position);text-decoration:none;white-space:pre">75,458,854</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:339.42pt;position:var(--position);text-decoration:none;white-space:pre"> shares, respectively, related to outstanding stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:171pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">options and warrants, as their effect would have been anti-dilutive.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:201pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.33pt;position:var(--position);text-decoration:none;white-space:pre">March 2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:180.91pt;position:var(--position);text-decoration:none;white-space:pre">, we completed an underwritten public offering of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:382.63pt;position:var(--position);text-decoration:none;white-space:pre">41,999,998</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:427.63pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:213pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and a pre-funded warrant to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:210pt;position:var(--position);text-decoration:none;white-space:pre">8,002,668</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:250pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock, or the 2024 pre-funded warrant. In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:510.91pt;position:var(--position);text-decoration:none;white-space:pre">January </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:225pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">, we completed an underwritten public offering of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:280.22pt;position:var(--position);text-decoration:none;white-space:pre">68,007,741</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:325.22pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock and a pre-funded warrant </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:237pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:106.78pt;position:var(--position);text-decoration:none;white-space:pre">25,000,000</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:151.78pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock, or the 2023 pre-funded warrant. In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:412.69pt;position:var(--position);text-decoration:none;white-space:pre">April 2022</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:456.28pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:249pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">underwriting public offering of our common stock, pursuant to which we issued a pre-funded warrant to purchase </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:261pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">18,095,238</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:103.5pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock, also known as the 2022 pre-funded warrant. In </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:412.71pt;position:var(--position);text-decoration:none;white-space:pre">May 2020</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:453.53pt;position:var(--position);text-decoration:none;white-space:pre">, we entered into an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:273pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">underwriting agreement public offering of our common stock, pursuant to which we issued a pre-funded warrant to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:285pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">purchase </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:96.50999999999999pt;position:var(--position);text-decoration:none;white-space:pre">8,335,239</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:136.51pt;position:var(--position);text-decoration:none;white-space:pre"> shares of our common stock, or the 2020 pre-funded warrant. The pre-funded warrants are exercisable </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:297pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">immediately at an exercise price of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:201.04pt;position:var(--position);text-decoration:none;white-space:pre">$0.001</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:228.54pt;position:var(--position);text-decoration:none;white-space:pre"> per share. We included the 2024 pre-funded warrant, the 2023 pre-funded </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:309pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">warrant, the 2022 pre-funded warrant and the 2020 pre-funded warrant in the computation of basic net loss per share, as </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:321pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">applicable, since their exercise price is negligible, and they may be exercised at any time. See Note 11 on Stockholders' </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:333pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Equity for further discussion of our public offerings.</span></div> 86350703 77369889 75458854 41999998 8002668 68007741 25000000 18095238 8335239 0.001 0.001 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">INCOME TAXES</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:85.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The com</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:156.73pt;position:var(--position);text-decoration:none;white-space:pre">ponents of incom</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:226.12pt;position:var(--position);text-decoration:none;white-space:pre">e (loss) before income taxes were as follows:</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:276.75pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);width:215.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:51.57pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:14.25pt;width:276.75pt"><div><div style="line-height:8pt;position:var(--position);top:5.62pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:28.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Domestic</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:32.96pt;position:var(--position);text-decoration:none;white-space:pre">(82,358)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(174,737)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(181,884)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:43.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:37.96pt;position:var(--position);text-decoration:none;white-space:pre">(1,067)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">215</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">150</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:58.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:32.96pt;position:var(--position);text-decoration:none;white-space:pre">(83,425)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(174,522)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(181,734)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:194pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Provision for (benefit from) income taxes was as follows:</span></div><div style="position:var(--position);top:212pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:276.75pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);width:215.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:51.57pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:14.25pt;width:276.75pt"><div><div style="line-height:8pt;position:var(--position);top:5.62pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:28.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">State</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">398</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:43.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">75</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">51</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">22</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:58.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">75</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">449</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">22</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:296.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table reconciles the federal statutory tax rate to the effective income tax rate from continuing </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:308.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">operations:</span></div><div style="position:var(--position);top:326.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:146.25pt"></td><td style="padding:0;width:62.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:48pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:62.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:48pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:62.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:48pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="11" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);width:345.75pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:345.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:122.43pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:14.25pt;width:113.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:113.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:47.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:14.25pt;width:113.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:113.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:47.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:14.25pt;width:113.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:113.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:47.62pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:28.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:15.39pt;position:var(--position);text-decoration:none;white-space:pre">Amount</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:28.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:15.39pt;position:var(--position);text-decoration:none;white-space:pre">Amount</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:28.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:15.39pt;position:var(--position);text-decoration:none;white-space:pre">Amount</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:42.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:3.26pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:42.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:2.78pt;position:var(--position);text-decoration:none;white-space:pre">Percentage</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:42.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:3.26pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:42.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:2.78pt;position:var(--position);text-decoration:none;white-space:pre">Percentage</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:42.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:3.26pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:42.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:2.78pt;position:var(--position);text-decoration:none;white-space:pre">Percentage</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:57pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Tax at statutory rate</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:57pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:28.14pt"></span></span><span style="left:30.77pt;position:var(--position)">(17,535)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:57pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:21.02pt;position:var(--position)"></span><span style="left:21.02pt;position:var(--position)">21.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:57pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:28.14pt"></span></span><span style="left:30.77pt;position:var(--position)">(36,660)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:57pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:21.02pt;position:var(--position)"></span><span style="left:21.02pt;position:var(--position)">21.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:57pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:28.14pt"></span></span><span style="left:30.77pt;position:var(--position)">(38,667)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:57pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:21.02pt;position:var(--position)"></span><span style="left:21.02pt;position:var(--position)">21.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:71.25pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">State income tax, net of federal benefit</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:71.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:71.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:71.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">398<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:71.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.2)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:71.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:71.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Federal and state tax credits</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:85.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:32.64pt"></span></span><span style="left:35.27pt;position:var(--position)">(2,233)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:85.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">2.7<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:85.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:32.64pt"></span></span><span style="left:35.27pt;position:var(--position)">(4,128)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:85.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">2.4<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:85.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:32.64pt"></span></span><span style="left:35.27pt;position:var(--position)">(7,591)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:85.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">4.1<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:99.75pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Stock-based compensation</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:99.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">2,588<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:99.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(3.1)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:99.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:39.39pt"></span></span><span style="left:42.02pt;position:var(--position)">(224)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:99.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">0.1<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:99.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">564<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:99.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.3)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:114pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Stock Based compensation - 162(m)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:114pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">1,578<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:114pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(1.9)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:114pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">3,014<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:114pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(1.7)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:114pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">1,750<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:114pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.9)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:128.25pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net operating loss not benefitted</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:128.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">7,717<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:128.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(9.2)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:128.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">862<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:128.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.5)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:128.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:31.13pt"></span></span><span style="left:33.76pt;position:var(--position)">10,451<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:128.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(5.7)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:142.5pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign rate difference</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:142.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">315<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:142.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.4)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:142.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">16<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:142.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:142.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:48.39pt"></span></span><span style="left:51.02pt;position:var(--position)">(9)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:142.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:156.75pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Change in unrecognized tax benefit</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:156.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:48.39pt"></span></span><span style="left:51.02pt;position:var(--position)">(3)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:156.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:156.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:39.39pt"></span></span><span style="left:42.02pt;position:var(--position)">(615)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:156.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">0.4<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:156.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">13<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:156.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:171pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:171pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">312<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:171pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.4)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:171pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">180<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:171pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.1)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:171pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">52<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:171pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:185.25pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Change in valuation allowance</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:185.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">7,336<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:185.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(8.8)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:185.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:31.13pt"></span></span><span style="left:33.76pt;position:var(--position)">37,606<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:185.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:18.03pt;position:var(--position)"></span><span style="left:18.03pt;position:var(--position)">(21.7)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:185.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:31.13pt"></span></span><span style="left:33.76pt;position:var(--position)">33,459<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:185.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:18.03pt;position:var(--position)"></span><span style="left:18.03pt;position:var(--position)">(18.2)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:199.5pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Effective tax rate</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:199.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">75<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:199.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.1)</span><span style="left:39.760000000000005pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:199.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">449<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:199.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.3)</span><span style="left:39.760000000000005pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:199.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">22<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:199.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">0.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:459.74pt;position:var(--position);text-decoration:none;white-space:pre">Significant </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">components of our deferred tax assets are as follows:</span></div><div style="position:var(--position);top:115.5pt;width:612pt"><div style="font-size:0pt;left:112.12pt;position:var(--position);width:387.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:242.25pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);width:142.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:142.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:47.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:242.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:242.25pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:3pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:28.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net operating loss carryforwards</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:33.17pt;position:var(--position)">278,382<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:33.17pt;position:var(--position)">272,970<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:43.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Federal and state tax credits</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">72,360<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">70,492<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:58.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Capitalized research and development</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">34,747<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">39,503<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:73.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Stock-based compensation</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">11,063<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:40.54pt"></span></span><span style="left:43.17pt;position:var(--position)">8,353<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:88.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Revenue Participation</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:88.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">32,758<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:88.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">29,547<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:103.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating lease liabilities</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:103.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">618<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:103.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">767<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:118.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:118.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">15,266<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:118.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:40.54pt"></span></span><span style="left:43.17pt;position:var(--position)">8,963<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:133.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total deferred tax assets</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:133.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">445,194<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:133.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">430,595<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:148.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: valuation allowance</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:148.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:27.21pt"></span></span><span style="left:29.84pt;position:var(--position)">(444,650)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:148.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:27.21pt"></span></span><span style="left:29.84pt;position:var(--position)">(429,913)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:163.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net deferred tax assets</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:163.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">544<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:163.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">682<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:193.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating leases, right-of-use assets</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:193.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(544)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:193.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(682)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:208.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total deferred tax liabilities</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:208.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(544)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:208.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(682)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:223.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total net deferred tax assets</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:223.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:223.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:371pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We record net deferred tax assets to the extent we believe these assets will more likely than not be realized. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:383pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">In making such determination, we consider all available positive and negative evidence, including scheduled reversals of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:395pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">deferred tax liabilities, projected future taxable income, tax planning strategies and recent financial performance. Forming a </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:407pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">conclusion that a valuation allowance is not required is difficult when there is negative evidence such as cumulative losses </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:419pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">in recent years. Because of our history of losses, the net deferred tax assets have been fully offset by a valuation allowance. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:431pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">The valuation allowance increased by </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:211.89pt;position:var(--position);text-decoration:none;white-space:pre">$14.7 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:265.74pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:285.16999999999996pt;position:var(--position);text-decoration:none;white-space:pre">$35.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:339.02pt;position:var(--position);text-decoration:none;white-space:pre"> for the years ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:420.32pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:498.86pt;position:var(--position);text-decoration:none;white-space:pre"> and </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:518.29pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:538.29pt;position:var(--position);text-decoration:none;white-space:pre">, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:443pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">respectively.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:467pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:145.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:224.48000000000002pt;position:var(--position);text-decoration:none;white-space:pre">, we had domestic federal net operating loss carryforwards of approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:531.9pt;position:var(--position);text-decoration:none;white-space:pre">$1.0 </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:479pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">billion</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:84.58pt;position:var(--position);text-decoration:none;white-space:pre">. Of this, </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:122.06pt;position:var(--position);text-decoration:none;white-space:pre">$561.7 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:180.91pt;position:var(--position);text-decoration:none;white-space:pre"> will expire at various dates beginning in 2026 through 2037 and the remaining will </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:491pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">carryforward indefinitely under the new tax laws, but is subject to an 80% taxable income limitation for tax years </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:503pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">beginning after December 31, 2017. As of </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:229.74pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:308.28pt;position:var(--position);text-decoration:none;white-space:pre">, we had state net operating loss carryforwards of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:515pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:118.7pt;position:var(--position);text-decoration:none;white-space:pre">$871.8 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:177.55pt;position:var(--position);text-decoration:none;white-space:pre"> expiring at various dates beginning in 2028 through 2045. We also had federal tax credit </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:527pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">carryforwards of approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:188.08pt;position:var(--position);text-decoration:none;white-space:pre">$81.9 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:241.93pt;position:var(--position);text-decoration:none;white-space:pre"> expiring at various dates beginning in 2026 through 2045, if not utilized. Our </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:539pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">state tax credit carryforwards of approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:248.8pt;position:var(--position);text-decoration:none;white-space:pre">$22.6 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:302.65pt;position:var(--position);text-decoration:none;white-space:pre"> carry forward indefinitely.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:563pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Utilization of net operating loss and tax credit carryforwards may be subject to an annual limitation due to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:575pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ownership change limitations provided by the Internal Revenue Code and similar state provisions. Annual limitations may </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:587pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">result in expiration of net operating loss and tax credit carryforwards before some or all of such amounts have been </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:599pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">utilized.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:623pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We adopted the provision of the standard for accounting for uncertainties in income taxes on January 1, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:635pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2007. Upon adoption, we recognized no material adjustment in the liability for unrecognized tax benefits. At </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:495.5pt;position:var(--position);text-decoration:none;white-space:pre">December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:647pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:78.5pt;position:var(--position);text-decoration:none;white-space:pre">, we had approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:174.78pt;position:var(--position);text-decoration:none;white-space:pre">$28.8 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:228.63pt;position:var(--position);text-decoration:none;white-space:pre"> of unrecognized tax benefits, none of which would currently affect our effective </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:659pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">tax rate if recognized due to our net deferred tax assets being fully offset by a valuation allowance.</span></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">A reconciliation of the beginning and ending amounts of unrecognized tax benefits is as follows (in </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">thousands):</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:157.87pt;position:var(--position);width:296.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:219pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:74.25pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance as of December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.04pt"></span></span><span style="left:42.67pt;position:var(--position)">28,310<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:16.13pt;position:var(--position);text-decoration:none;white-space:pre">Decrease related to prior year tax positions</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);top:15pt;width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:49.21pt"></span></span><span style="left:51.84pt;position:var(--position)">(583)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:16.13pt;position:var(--position);text-decoration:none;white-space:pre">Increase related to current year tax positions</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);top:30pt;width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:45.04pt"></span></span><span style="left:47.67pt;position:var(--position)">1,094<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance as of December 31, 2025</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);top:45pt;width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.04pt"></span></span><span style="left:42.67pt;position:var(--position)">28,821<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:180.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">If applicable, we would classify interest and penalties related to uncertain tax positions in income tax </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:192.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expense. Through </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:132.61pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:211.15pt;position:var(--position);text-decoration:none;white-space:pre">, there has been no interest expense or penalties related to unrecognized tax benefits.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:216.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We do not currently expect any significant changes to unrecognized tax benefits during the fiscal year </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:228.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:84.86pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:163.4pt;position:var(--position);text-decoration:none;white-space:pre">. In certain cases, our uncertain tax positions are related to tax years that remain subject to </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:240.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">examination by the relevant tax authorities. Tax years for which we have carryforward net operating loss and credit </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:252.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">attributes remain subject to examination by federal and most state tax authorities.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:276.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On July 4, 2025, the One Big Beautiful Bill Act, or OBBBA, was signed into law in the United States. This </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:288.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">comprehensive tax legislation contains a broad range of tax reforms, including provisions that allow for the immediate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:300.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">expensing of domestic research and development expenses, restore and make permanent 100% bonus depreciation for </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:312.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">qualifying assets, and ease limitations on the deductibility of interest expense. The legislation has multiple effective dates, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:324.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with certain provisions taking effect in 2025 and others being implemented through various future years. We have </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:336.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">accounted for the provisions of the OBBBA in our consolidated financial statements. The changes did not impact income </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:348.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">taxes due to its cumulative tax loss and tax effect of a full valuation allowance against those balances.</span></div> <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The com</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:156.73pt;position:var(--position);text-decoration:none;white-space:pre">ponents of incom</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:226.12pt;position:var(--position);text-decoration:none;white-space:pre">e (loss) before income taxes were as follows:</span><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:276.75pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);width:215.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:51.57pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:14.25pt;width:276.75pt"><div><div style="line-height:8pt;position:var(--position);top:5.62pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:28.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Domestic</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:32.96pt;position:var(--position);text-decoration:none;white-space:pre">(82,358)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(174,737)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(181,884)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:43.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:37.96pt;position:var(--position);text-decoration:none;white-space:pre">(1,067)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">215</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">150</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:58.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:32.96pt;position:var(--position);text-decoration:none;white-space:pre">(83,425)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(174,522)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:27.96pt;position:var(--position);text-decoration:none;white-space:pre">(181,734)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> -82358000 -174737000 -181884000 -1067000 215000 150000 -83425000 -174522000 -181734000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Provision for (benefit from) income taxes was as follows:</span><div style="position:var(--position);top:212pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:276.75pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);width:215.25pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:51.57pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:14.25pt;width:276.75pt"><div><div style="line-height:8pt;position:var(--position);top:5.62pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:14.25pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:24.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:28.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">State</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">398</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">—</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:43.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">75</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">51</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">22</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:58.5pt;width:276.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:276.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:276.75pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">75</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:349.5pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:52.12pt;position:var(--position);text-decoration:none;white-space:pre">449</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:422.25pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:57.12pt;position:var(--position);text-decoration:none;white-space:pre">22</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 0 398000 0 75000 51000 22000 75000 449000 22000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The following table reconciles the federal statutory tax rate to the effective income tax rate from continuing </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:308.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">operations:</span></div><div style="position:var(--position);top:326.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:146.25pt"></td><td style="padding:0;width:62.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:48pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:62.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:48pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:62.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:48pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="11" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);width:345.75pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:345.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:122.43pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:14.25pt;width:113.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:113.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:47.62pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:14.25pt;width:113.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:113.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:47.62pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:14.25pt;width:113.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:113.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:47.62pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:28.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:15.39pt;position:var(--position);text-decoration:none;white-space:pre">Amount</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:28.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:15.39pt;position:var(--position);text-decoration:none;white-space:pre">Amount</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:28.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:15.39pt;position:var(--position);text-decoration:none;white-space:pre">Amount</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:42.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:3.26pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:42.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:2.78pt;position:var(--position);text-decoration:none;white-space:pre">Percentage</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:42.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:3.26pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:42.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:2.78pt;position:var(--position);text-decoration:none;white-space:pre">Percentage</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:42.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:3.26pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:42.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.72pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:bold;left:2.78pt;position:var(--position);text-decoration:none;white-space:pre">Percentage</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:57pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Tax at statutory rate</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:57pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:28.14pt"></span></span><span style="left:30.77pt;position:var(--position)">(17,535)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:57pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:21.02pt;position:var(--position)"></span><span style="left:21.02pt;position:var(--position)">21.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:57pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:28.14pt"></span></span><span style="left:30.77pt;position:var(--position)">(36,660)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:57pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:21.02pt;position:var(--position)"></span><span style="left:21.02pt;position:var(--position)">21.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:57pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:28.14pt"></span></span><span style="left:30.77pt;position:var(--position)">(38,667)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:57pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:21.02pt;position:var(--position)"></span><span style="left:21.02pt;position:var(--position)">21.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:71.25pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">State income tax, net of federal benefit</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:71.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:71.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:71.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">398<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:71.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.2)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:71.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:71.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Federal and state tax credits</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:85.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:32.64pt"></span></span><span style="left:35.27pt;position:var(--position)">(2,233)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:85.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">2.7<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:85.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:32.64pt"></span></span><span style="left:35.27pt;position:var(--position)">(4,128)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:85.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">2.4<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:85.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:32.64pt"></span></span><span style="left:35.27pt;position:var(--position)">(7,591)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:85.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">4.1<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:99.75pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Stock-based compensation</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:99.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">2,588<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:99.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(3.1)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:99.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:39.39pt"></span></span><span style="left:42.02pt;position:var(--position)">(224)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:99.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">0.1<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:99.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">564<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:99.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.3)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:114pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Stock Based compensation - 162(m)</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:114pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">1,578<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:114pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(1.9)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:114pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">3,014<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:114pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(1.7)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:114pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">1,750<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:114pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.9)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:128.25pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net operating loss not benefitted</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:128.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">7,717<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:128.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(9.2)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:128.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">862<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:128.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.5)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:128.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:31.13pt"></span></span><span style="left:33.76pt;position:var(--position)">10,451<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:128.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(5.7)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:142.5pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign rate difference</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:142.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">315<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:142.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.4)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:142.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">16<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:142.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:142.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:48.39pt"></span></span><span style="left:51.02pt;position:var(--position)">(9)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:142.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:156.75pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Change in unrecognized tax benefit</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:156.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:48.39pt"></span></span><span style="left:51.02pt;position:var(--position)">(3)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:156.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:156.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:39.39pt"></span></span><span style="left:42.02pt;position:var(--position)">(615)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:156.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">0.4<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:156.75pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">13<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:156.75pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:171pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:171pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">312<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:171pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.4)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:171pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">180<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:171pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.1)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:171pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">52<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:171pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:27.77pt;position:var(--position)"></span><span style="left:27.77pt;position:var(--position)">—<span style="display:inline-block;height:6.24pt;width:10.48pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:185.25pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Change in valuation allowance</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:185.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:35.63pt"></span></span><span style="left:38.260000000000005pt;position:var(--position)">7,336<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:185.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(8.8)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:185.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:31.13pt"></span></span><span style="left:33.76pt;position:var(--position)">37,606<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:185.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:18.03pt;position:var(--position)"></span><span style="left:18.03pt;position:var(--position)">(21.7)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:185.25pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:31.13pt"></span></span><span style="left:33.76pt;position:var(--position)">33,459<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:185.25pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:18.03pt;position:var(--position)"></span><span style="left:18.03pt;position:var(--position)">(18.2)<span style="display:inline-block;height:6.24pt;width:7.49pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:199.5pt;width:146.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:146.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Effective tax rate</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:146.25pt;position:var(--position);top:199.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">75<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:211.5pt;position:var(--position);top:199.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.1)</span><span style="left:39.760000000000005pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:262.5pt;position:var(--position);top:199.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:42.38pt"></span></span><span style="left:45.010000000000005pt;position:var(--position)">449<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:327.75pt;position:var(--position);top:199.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:22.53pt;position:var(--position)"></span><span style="left:22.53pt;position:var(--position)">(0.3)</span><span style="left:39.760000000000005pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:378.75pt;position:var(--position);top:199.5pt;width:62.25pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:62.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.24pt;width:46.88pt"></span></span><span style="left:49.510000000000005pt;position:var(--position)">22<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:444pt;position:var(--position);top:199.5pt;width:48pt"><div><div style="line-height:9pt;position:var(--position);top:4.57pt;width:48pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:9pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:25.52pt;position:var(--position)"></span><span style="left:25.52pt;position:var(--position)">0.0<span style="display:inline-block;height:6.24pt;width:2.99pt"></span></span><span style="left:39.76pt;position:var(--position)">%</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> -17535000 0.210 -36660000 0.210 -38667000 0.210 0 0 398000 -0.002 0 0 2233000 -0.027 4128000 -0.024 7591000 -0.041 2588000 -0.031 -224000 0.001 564000 -0.003 1578000 -0.019 3014000 -0.017 1750000 -0.009 7717000 -0.092 862000 -0.005 10451000 -0.057 315000 -0.004 16000 0 -9000 0 -3000 0 -615000 0.004 13000 0 312000 -0.004 180000 -0.001 52000 0 7336000 -0.088 37606000 -0.217 33459000 -0.182 75000 -0.001 449000 -0.003 22000 0.000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:459.74pt;position:var(--position);text-decoration:none;white-space:pre">Significant </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">components of our deferred tax assets are as follows:</span></div><div style="position:var(--position);top:115.5pt;width:612pt"><div style="font-size:0pt;left:112.12pt;position:var(--position);width:387.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:242.25pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);width:142.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:142.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:47.94pt;position:var(--position);text-decoration:none;white-space:pre">December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:242.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:242.25pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:3pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:28.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net operating loss carryforwards</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:33.17pt;position:var(--position)">278,382<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:28.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:25.54pt"></span></span><span style="left:33.17pt;position:var(--position)">272,970<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:43.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Federal and state tax credits</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">72,360<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:43.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">70,492<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:58.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Capitalized research and development</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">34,747<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:58.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">39,503<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:73.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Stock-based compensation</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">11,063<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:73.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:40.54pt"></span></span><span style="left:43.17pt;position:var(--position)">8,353<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:88.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Revenue Participation</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:88.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">32,758<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:88.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">29,547<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:103.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating lease liabilities</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:103.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">618<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:103.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">767<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:118.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:118.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:38.17pt;position:var(--position)">15,266<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:118.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:40.54pt"></span></span><span style="left:43.17pt;position:var(--position)">8,963<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:133.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total deferred tax assets</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:133.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">445,194<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:133.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:33.17pt;position:var(--position)">430,595<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:148.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Less: valuation allowance</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:148.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:27.21pt"></span></span><span style="left:29.84pt;position:var(--position)">(444,650)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:148.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:27.21pt"></span></span><span style="left:29.84pt;position:var(--position)">(429,913)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:163.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net deferred tax assets</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:163.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">544<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:163.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:50.67pt;position:var(--position)">682<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:193.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating leases, right-of-use assets</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:193.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(544)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:193.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(682)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:208.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Total deferred tax liabilities</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:208.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(544)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:208.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(682)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:223.5pt;width:242.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:242.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total net deferred tax assets</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:242.25pt;position:var(--position);top:223.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:315pt;position:var(--position);top:223.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> 278382000 272970000 72360000 70492000 34747000 39503000 11063000 8353000 32758000 29547000 618000 767000 15266000 8963000 445194000 430595000 444650000 429913000 544000 682000 544000 682000 544000 682000 0 0 14700000 35000000.0 1000000000.0 561700000 871800000 81900000 22600000 28800000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">A reconciliation of the beginning and ending amounts of unrecognized tax benefits is as follows (in </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">thousands):</span></div><div style="position:var(--position);top:103.5pt;width:612pt"><div style="font-size:0pt;left:157.87pt;position:var(--position);width:296.25pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:219pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:74.25pt"></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance as of December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.04pt"></span></span><span style="left:42.67pt;position:var(--position)">28,310<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:15pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:16.13pt;position:var(--position);text-decoration:none;white-space:pre">Decrease related to prior year tax positions</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);top:15pt;width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:49.21pt"></span></span><span style="left:51.84pt;position:var(--position)">(583)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:30pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:16.13pt;position:var(--position);text-decoration:none;white-space:pre">Increase related to current year tax positions</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);top:30pt;width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:45.04pt"></span></span><span style="left:47.67pt;position:var(--position)">1,094<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:45pt;width:219pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:219pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Balance as of December 31, 2025</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:222pt;position:var(--position);top:45pt;width:74.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:74.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.04pt"></span></span><span style="left:42.67pt;position:var(--position)">28,821<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 28310000 583000 1094000 28821000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">CONSOLIDATED STATEMENT</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:219.8pt;position:var(--position);text-decoration:none;white-space:pre">S OF CASH FLOWS DATA</span><div style="position:var(--position);top:402.5pt;width:612pt"><div style="font-size:0pt;left:90pt;position:var(--position);width:432pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:213.75pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);width:215.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:62.78pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:3pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:28.5pt;width:215.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:82.87pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:41.25pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Supplemental operating and investing activities:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Net unrealized loss on marketable securities</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:52.34pt;position:var(--position)">(45)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:55.67pt;position:var(--position)">88<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:39.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(431)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:7.13pt;position:var(--position);text-decoration:none;white-space:pre">Reclassification between prepaid and other current </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:16.13pt;position:var(--position);text-decoration:none;white-space:pre">assets and deposits and other assets</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:70.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:70.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:70.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:97.5pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Interest paid</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:97.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:38.17pt;position:var(--position)">11,712<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:97.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:38.17pt;position:var(--position)">10,364<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:97.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">7,017<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div></div> <div style="font-size:0pt;left:90pt;position:var(--position);width:432pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:213.75pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:69.75pt"></td><td style="padding:0;width:3pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);width:215.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:62.78pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:12.75pt;width:69.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:26.87pt;position:var(--position);text-decoration:none;white-space:pre">2023</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:3pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="5" style="font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:28.5pt;width:215.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:215.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:82.87pt;position:var(--position);text-decoration:none;white-space:pre">(In thousands)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:14.25pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:41.25pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:3.83pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Supplemental operating and investing activities:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Net unrealized loss on marketable securities</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:44.71pt"></span></span><span style="left:52.34pt;position:var(--position)">(45)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:48.04pt"></span></span><span style="left:55.67pt;position:var(--position)">88<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:55.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:39.71pt"></span></span><span style="left:47.34pt;position:var(--position)">(431)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:27pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:7.13pt;position:var(--position);text-decoration:none;white-space:pre">Reclassification between prepaid and other current </span></div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:16.13pt;position:var(--position);text-decoration:none;white-space:pre">assets and deposits and other assets</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:70.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:70.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:70.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:16.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:53.04pt"></span></span><span style="left:55.67pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:97.5pt;width:213.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:213.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Interest paid</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:213.75pt;position:var(--position);top:97.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:38.17pt;position:var(--position)">11,712<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:286.5pt;position:var(--position);top:97.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:30.54pt"></span></span><span style="left:38.17pt;position:var(--position)">10,364<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:359.25pt;position:var(--position);top:97.5pt;width:69.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:69.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:35.54pt"></span></span><span style="left:43.17pt;position:var(--position)">7,017<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td></tr></tbody></table></div></div> -45000 88000 -431000 0 0 0 11712000 10364000 7017000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">SEGMENT REPORTING</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:556pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">We are currently developing therapies for the treatment of hematologic malignancies. To date, our only </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:568pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">source of product revenue has been from U.S. sales of RYTELO, which began shipping to customers in June 2024. </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:580pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Additionally, we have generated insignificant royalty and license fee revenue under agreements that out-license technology </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:592pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">to various companies.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:610pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">For the year ended </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:198.64pt;position:var(--position);text-decoration:none;white-space:pre">December 31, 2025</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:277.18pt;position:var(--position);text-decoration:none;white-space:pre">, we have identified </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:358.46000000000004pt;position:var(--position);text-decoration:none;white-space:pre">one</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:372.89pt;position:var(--position);text-decoration:none;white-space:pre"> operating and reportable segment. We </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:622pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">define our operating segments based on internally reported financial information that is regularly reviewed by the Chief </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:634pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Operating Decision Maker or CODM to analyze financial performance, make decisions, and allocate resources. Our </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:524.5799999999999pt;position:var(--position);text-decoration:none;white-space:pre">Chief </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:646pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Executive Officer</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:129.76999999999998pt;position:var(--position);text-decoration:none;white-space:pre"> is the CODM.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:664pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">The CODM reviews the segment's profit or loss based on net (loss) income reported on the consolidated </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:676pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">statement of operations and comprehensive (loss) income and considers forecast-to-actuals variances on a quarterly basis </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:688pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">for expenses that are deemed significant. Further, the CODM reviews the segment's assets based on total assets reported on </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:700pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">the consolidated balance sheet. All long-lived assets are held in the U.S.</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:346.47pt;position:var(--position);text-decoration:none;white-space:pre"> Further, the CODM reviews the segment's assets </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:712pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">based on total assets reported on the consolidated balance sheet. All long-lived assets are held in the United States.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:67.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">Our CODM views specific categories within research and development expenses and selling, general and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:79.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">administrative expenses as significant given the correlation between cash burn and profitability. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:443.84pt;position:var(--position);text-decoration:none;white-space:pre"> </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:446.34pt;position:var(--position);text-decoration:none;white-space:pre">The following table </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reconciles reported revenues to net (loss) income under the significant expense principle for the year ended December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025 and 2024:</span></div><div style="position:var(--position);top:127.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:331.5pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);width:163.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:163.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:36.9pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in millions)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Revenues:</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Product revenue, net</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:51.04pt"></span></span><span style="left:53.67pt;position:var(--position)">183.6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">76.5<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Royalties</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">0.3<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">0.5<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total revenues</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:46.04pt"></span></span><span style="left:53.67pt;position:var(--position)">183.9<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:51.04pt"></span></span><span style="left:58.67pt;position:var(--position)">77.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating expenses:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:100.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Cost of goods sold</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:100.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">4.7<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:100.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">1.3<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:115.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Research and development</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:130.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Research and clinical expenses</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:130.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">54.2<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:130.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">67.9<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:145.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Chemistry, manufacturing, and control expenses</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:145.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">9.8<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:145.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">26.2<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:160.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring charges</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:160.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">8.6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:160.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:63.54pt"></span></span><span style="left:66.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:175.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Selling, general and administrative</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:190.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial expenses</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:190.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">78.6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:190.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">72.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:205.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring charges</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:205.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">8.4<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:205.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:63.54pt"></span></span><span style="left:66.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:220.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other segment expenses*</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:220.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">88.2<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:220.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">83.3<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:235.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total operating expenses</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:235.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:46.04pt"></span></span><span style="left:53.67pt;position:var(--position)">252.5<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:235.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:46.04pt"></span></span><span style="left:53.67pt;position:var(--position)">250.7<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:250.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Loss from operations</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:250.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.71pt"></span></span><span style="left:55.34pt;position:var(--position)">(68.6)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:250.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.71pt"></span></span><span style="left:50.34pt;position:var(--position)">(173.7)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:265.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total interest and other income (expense)</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:265.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.71pt"></span></span><span style="left:55.34pt;position:var(--position)">(14.9)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:265.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:57.71pt"></span></span><span style="left:60.34pt;position:var(--position)">(0.9)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:280.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net loss</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:280.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:47.71pt"></span></span><span style="left:55.34pt;position:var(--position)">(83.5)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:280.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.71pt"></span></span><span style="left:50.34pt;position:var(--position)">(174.6)</span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:428pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">*</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:67.5pt;position:var(--position);text-decoration:none;white-space:pre">Other segment expenses includes stock-based compensation expense and other general and administrative expenses </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:440pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:67.5pt;position:var(--position);text-decoration:none;white-space:pre">largely resulting from personnel costs for individuals in administrative functions and legal and professional fees.</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:458pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Accordingly, the Company consists of a single operating and reportable segment and the consolidated financial statements </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:470pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and notes thereto are presented as a single reportable segment.</span></div> 1 1 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:446.34pt;position:var(--position);text-decoration:none;white-space:pre">The following table </span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:91.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">reconciles reported revenues to net (loss) income under the significant expense principle for the year ended December 31, </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:103.5pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2025 and 2024:</span></div><div style="position:var(--position);top:127.5pt;width:612pt"><div style="font-size:0pt;left:58.5pt;position:var(--position);width:495pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:331.5pt"></td><td style="padding:0;width:80.25pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:80.25pt"></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"></td><td colspan="3" style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);width:163.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:163.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:36.9pt;position:var(--position);text-decoration:none;white-space:pre">Year Ended December 31,</span></div></div></div></td></tr><tr style="height:12.75pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:331.5pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(in millions)</span></div></div></div></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2025</span></div></div></div></td><td style="border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:12.75pt;width:80.25pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:32.12pt;position:var(--position);text-decoration:none;white-space:pre">2024</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:25.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Revenues:</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:40.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Product revenue, net</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:51.04pt"></span></span><span style="left:53.67pt;position:var(--position)">183.6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:40.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">76.5<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:55.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Royalties</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">0.3<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:55.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">0.5<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:70.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total revenues</span></div></div></div></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:46.04pt"></span></span><span style="left:53.67pt;position:var(--position)">183.9<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:70.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:51.04pt"></span></span><span style="left:58.67pt;position:var(--position)">77.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:85.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Operating expenses:</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:100.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Cost of goods sold</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:100.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">4.7<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:100.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">1.3<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:115.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Research and development</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:130.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Research and clinical expenses</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:130.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">54.2<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:130.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">67.9<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:145.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Chemistry, manufacturing, and control expenses</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:145.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">9.8<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:145.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">26.2<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:160.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring charges</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:160.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">8.6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:160.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:63.54pt"></span></span><span style="left:66.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:175.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Selling, general and administrative</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:190.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Commercial expenses</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:190.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">78.6<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:190.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">72.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:205.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:11.63pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring charges</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:205.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:61.04pt"></span></span><span style="left:63.67pt;position:var(--position)">8.4<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:205.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:63.54pt"></span></span><span style="left:66.17pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:220.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Other segment expenses*</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:220.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">88.2<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:220.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:56.04pt"></span></span><span style="left:58.67pt;position:var(--position)">83.3<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:235.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total operating expenses</span></div></div></div></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:235.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:46.04pt"></span></span><span style="left:53.67pt;position:var(--position)">252.5<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:235.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:46.04pt"></span></span><span style="left:53.67pt;position:var(--position)">250.7<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:250.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Loss from operations</span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:250.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.71pt"></span></span><span style="left:55.34pt;position:var(--position)">(68.6)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:250.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:47.71pt"></span></span><span style="left:50.34pt;position:var(--position)">(173.7)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:265.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Total interest and other income (expense)</span></div></div></div></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:265.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:52.71pt"></span></span><span style="left:55.34pt;position:var(--position)">(14.9)</span></span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:265.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:57.71pt"></span></span><span style="left:60.34pt;position:var(--position)">(0.9)</span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:280.5pt;width:331.5pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:331.5pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Net loss</span></div></div></div></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:331.5pt;position:var(--position);top:280.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:47.71pt"></span></span><span style="left:55.34pt;position:var(--position)">(83.5)</span></span></div></div></div></td><td style="background-color:#ffffff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#ffffff;border-bottom:1pt solid #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:414.75pt;position:var(--position);top:280.5pt;width:80.25pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:80.25pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:42.71pt"></span></span><span style="left:50.34pt;position:var(--position)">(174.6)</span></span></div></div></div></td></tr></tbody></table></div></div></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:428pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">*</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:67.5pt;position:var(--position);text-decoration:none;white-space:pre">Other segment expenses includes stock-based compensation expense and other general and administrative expenses </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:440pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:67.5pt;position:var(--position);text-decoration:none;white-space:pre">largely resulting from personnel costs for individuals in administrative functions and legal and professional fees.</span></div> 183600000 76500000 300000 500000 183900000 77000000.0 4700000 1300000 54200000 67900000 9800000 26200000 8600000 0 78600000 72000000.0 8400000 0 88200000 83300000 252500000 250700000 -68600000 -173700000 -14900000 -900000 -83500000 -174600000 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">RESTRUCTURING</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:93pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:94.5pt;position:var(--position);text-decoration:none;white-space:pre">In December 2025, the board of directors approved a workforce reduction representing approximately one-third of </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:104.2pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">our workforce prior to the reduction in headcount. We incurred approximately </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:373.71pt;position:var(--position);text-decoration:none;white-space:pre">$17.0 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:427.56pt;position:var(--position);text-decoration:none;white-space:pre"> in restructuring and </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:115.4pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">restructuring-related charges, primarily consisting of one-time employee severance payments, healthcare and related </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:126.6pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">benefits, and other employee-related costs. </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:231.88pt;position:var(--position);text-decoration:none;white-space:pre">The charges were recorded within restructuring charges line item within the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:137.8pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">consolidated statements of operations. We</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:227.45pt;position:var(--position);text-decoration:none;white-space:pre"> estimate the workforce reduction will be substantially completed in the first </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:149pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">quarter of 2026. There were </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:172.82pt;position:var(--position);text-decoration:none;white-space:pre">no</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:182.82pt;position:var(--position);text-decoration:none;white-space:pre"> restructuring charges in </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:282.15pt;position:var(--position);text-decoration:none;white-space:pre">2024</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:302.15pt;position:var(--position);text-decoration:none;white-space:pre"> or </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:315.48pt;position:var(--position);text-decoration:none;white-space:pre">2023</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:335.48pt;position:var(--position);text-decoration:none;white-space:pre">.</span></div><div style="position:var(--position);top:184.2pt;width:612pt"><div style="font-size:0pt;left:122.62pt;position:var(--position);width:366.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:264.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:99pt"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:264.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:264.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In millions)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);width:99pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:99pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:25.53pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued balance as of December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:12.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.58pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.77pt;width:77.29pt"></span></span><span style="left:84.92pt;position:var(--position)">—<span style="display:inline-block;height:6.77pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:27.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expenses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:27.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:74.79pt"></span></span><span style="left:77.42pt;position:var(--position)">17.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:42.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Payments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:42.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:82.29pt"></span></span><span style="left:84.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:57.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign currency and other adjustments</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:57.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:82.29pt"></span></span><span style="left:84.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:72.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued balance as of December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:72.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:69.79pt"></span></span><span style="left:77.42pt;position:var(--position)">17.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div></div> 17000000.0 0 0 <div style="font-size:0pt;left:122.62pt;position:var(--position);width:366.75pt"><div><table style="border-collapse:collapse;display:inline-table;width:100%"><tbody><tr style="height:0"><td style="padding:0;width:264.75pt"></td><td style="padding:0;width:3pt"></td><td style="padding:0;width:99pt"></td></tr><tr style="height:12.75pt"><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);width:264.75pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:264.75pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">(In millions)</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);width:99pt"><div><div style="line-height:8pt;position:var(--position);top:4.12pt;width:99pt"><span style="font-family:'Times New Roman', serif;font-size:8pt;font-style:normal;font-weight:bold;left:25.53pt;position:var(--position);text-decoration:none;white-space:pre">Restructuring</span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:12.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued balance as of December 31, 2024</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:12.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.58pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.77pt;width:77.29pt"></span></span><span style="left:84.92pt;position:var(--position)">—<span style="display:inline-block;height:6.77pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:27.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Expenses</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:27.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:74.79pt"></span></span><span style="left:77.42pt;position:var(--position)">17.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:42.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Payments</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:42.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:82.29pt"></span></span><span style="left:84.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:57.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Foreign currency and other adjustments</span></div></div></div></td><td style="font-size:0;text-align:left;vertical-align:top"></td><td style="border-bottom:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:57.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)"><span style="display:inline-block;height:6.93pt;width:82.29pt"></span></span><span style="left:84.92pt;position:var(--position)">—<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr><tr style="height:15pt"><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"><div style="position:var(--position);top:72.75pt;width:264.75pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:264.75pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:2.63pt;position:var(--position);text-decoration:none;white-space:pre">Accrued balance as of December 31, 2025</span></div></div></div></td><td style="background-color:#cceeff;font-size:0;text-align:left;vertical-align:top"></td><td style="background-color:#cceeff;border-bottom:3pt double #000;border-top:1pt solid #000;font-size:0;text-align:left;vertical-align:top"><div style="left:267.75pt;position:var(--position);top:72.75pt;width:99pt"><div><div style="line-height:10pt;position:var(--position);top:4.42pt;width:99pt"><span style="color:#000000;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;text-decoration:none;white-space:pre"><span style="left:2.63pt;position:var(--position)">$<span style="display:inline-block;height:6.93pt;width:69.79pt"></span></span><span style="left:77.42pt;position:var(--position)">17.0<span style="display:inline-block;height:6.93pt;width:3.33pt"></span></span></span></div></div></div></td></tr></tbody></table></div></div> 0 17000000.0 0 0 17000000.0 <span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:bold;left:73.5pt;position:var(--position);text-decoration:none;white-space:pre">SUBSEQUENT EVENTS</span><div style="font-size:12pt;line-height:10pt;position:var(--position);top:312.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Pharmakon Loan Agreement Amendment</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:336.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On January 5, 2026, we entered into the First Amendment to the Loan Agreement (the “First Amendment”) </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:348.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">with Lenders and Biopharma Credit PLC. Pursuant to the First Amendment, the date for requesting the Tranche B Loan </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:360.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">and the Tranche C Loan was extended from December 31, 2025 to July 30, 2026. The amendment also extended the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:372.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">Makewhole Date from November 1, 2026 to May 1, 2027.  </span><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:297.22pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">See Note 10 on Debt for additional information on the </span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:384.95pt;width:612pt"><span style="background-color:#ffffff;font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre"><span style="background-color:inherit">Pharmakon Loan Agreement.</span></span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:408.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:italic;font-weight:bold;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2026 Sales Agreement</span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:432.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:121.5pt;position:var(--position);text-decoration:none;white-space:pre">On February 27, 2026, we entered into a sales agreement, or the 2026 Sales Agreement, with TD Securities </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:444.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">(USA) LLC, or TD Cowen, pursuant to which we may issue and sell shares of our common stock having an aggregate </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:456.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">offering price of up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:149.25pt;position:var(--position);text-decoration:none;white-space:pre">$150 million</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:200.6pt;position:var(--position);text-decoration:none;white-space:pre"> from time to time through TD Cowen as the sales agent. We will pay TD Cowen an </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:468.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">aggregate commission rate equal to up to </span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:225.24pt;position:var(--position);text-decoration:none;white-space:pre">2.5%</span><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:246.07pt;position:var(--position);text-decoration:none;white-space:pre"> of the gross proceeds of the sales price per share for common stock sold </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:480.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">through TD Cowen under the 2026 Sales Agreement. We are not obligated to make any sales of common stock under the </span></div><div style="font-size:12pt;line-height:10pt;position:var(--position);top:492.95pt;width:612pt"><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">2026 Sales Agreement. Our previous 2023 Sales Agreement with B. Riley Securities, dated November 1, 2023, was </span></div><span style="font-family:'Times New Roman', serif;font-size:10pt;font-style:normal;font-weight:normal;left:58.5pt;position:var(--position);text-decoration:none;white-space:pre">terminated in January 2026.</span> 150000000 0.025 false false false false true